SIRT5 Inhibition Induces Brown Fat-Like Phenotype in 3T3-L1 Preadipocytes

Mitophagy: An Emerging Role in Aging and Age-Associated Diseases

(2020) Guo Chen et al.   Frontiers in Cell and Developmental Biology

The novel non‐steroidal MR antagonist finerenone improves metabolic parameters in high‐fat diet‐fed mice and activates brown adipose tissue via AMPK‐ATGL pathway

(2020) Vincenzo Marzolla et al.   FASEB JOURNAL

Adipocyte-specific Beclin1 deletion impairs lipolysis and mitochondrial integrity in adipose tissue

(2020) Yeonho Son et al.   Molecular Metabolism

SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress

(2019) Mengli Zhang et al.   PLoS One

SIRT5 Regulates Brown Adipocyte Differentiation and Browning of Subcutaneous White Adipose Tissue

(2019) Lin Shuai et al.   DIABETES

Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation

(2019) GuoXiao Wang et al.   MOLECULAR CELL

SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1

(2019) Rajaa Sebaa et al.   Molecular Metabolism

Lipid droplets and mitochondria are anchored during brown adipocyte differentiation

(2019) Liujuan Cui et al.   Protein & Cell

Mineralocorticoid Receptors in Metabolic Syndrome: From Physiology to Disease

(2019) Alessandra Feraco et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Emerging Roles for SIRT5 in Metabolism and Cancer

(2018) Lauren R. Bringman-Rodenbarger et al.   ANTIOXIDANTS & REDOX SIGNALING

The Mitochondrial Acylome Emerges: Proteomics, Regulation by Sirtuins, and Metabolic and Disease Implications

(2018) Chris Carrico et al.   Cell Metabolism

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance

(2018) Sarah Pickles et al.   CURRENT BIOLOGY

Mitophagy is required for brown adipose tissue mitochondrial homeostasis during cold challenge

(2018) Yuan Lu et al.   Scientific Reports

AMP-Activated Protein Kinase (AMPK) Regulates Energy Metabolism through Modulating Thermogenesis in Adipose Tissue

(2018) Lingyan Wu et al.   Frontiers in Physiology

Fatty acid oxidation is required for active and quiescent brown adipose tissue maintenance and thermogenic programing

(2018) Elsie Gonzalez-Hurtado et al.   Molecular Metabolism

Mitochondrial fission is associated with UCP1 activity in human brite/beige adipocytes

(2018) Didier F. Pisani et al.   Molecular Metabolism

Emerging Role of AMPK in Brown and Beige Adipose Tissue (BAT): Implications for Obesity, Insulin Resistance, and Type 2 Diabetes

(2018) Eric M. Desjardins et al.   Current Diabetes Reports

Browning of white fat: agents and implications for beige adipose tissue to type 2 diabetes

(2018) A. Kaisanlahti et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues

(2017) Rajan Singh et al.   ENDOCRINOLOGY

Molecular mechanisms underlying metabolic syndrome: the expanding role of the adipocyte

(2017) Andrea Armani et al.   FASEB JOURNAL

AMPK promotes mitochondrial biogenesis and function by phosphorylating the epigenetic factors DNMT1, RBBP7, and HAT1

(2017) Traci L. Marin et al.   Science Signaling

AMPK promotes mitochondrial biogenesis and function by phosphorylating the epigenetic factors DNMT1, RBBP7, and HAT1

(2017) Traci L. Marin et al.   Science Signaling

Adipose tissue NAD + -homeostasis, sirtuins and poly(ADP-ribose) polymerases -important players in mitochondrial metabolism and metabolic health

(2017) Riikka Jokinen et al.   Redox Biology

Energetic mitochondrial failing in vitiligo and possible rescue by cardiolipin

(2017) Maria Lucia Dell’Anna et al.   Scientific Reports

AMPK/α-Ketoglutarate Axis Dynamically Mediates DNA Demethylation in the Prdm16 Promoter and Brown Adipogenesis

(2016) Qiyuan Yang et al.   Cell Metabolism

Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function

(2016) Emilio P. Mottillo et al.   Cell Metabolism

Convertible visceral fat as a therapeutic target to curb obesity

(2016) Antonio Giordano et al.   NATURE REVIEWS DRUG DISCOVERY

SIRT5 regulation of ammonia-induced autophagy and mitophagy

(2015) Lucia Polletta et al.   Autophagy

Brown and Beige Fat: Physiological Roles beyond Heat Generation

(2015) Shingo Kajimura et al.   Cell Metabolism

Transcriptional Regulatory Circuits Controlling Brown Fat Development and Activation

(2015) Patrick Seale   DIABETES

AMP-Activated Protein Kinase Directly Phosphorylates and Destabilizes Hedgehog Pathway Transcription Factor GLI1 in Medulloblastoma

(2015) Yen-Hsing Li et al.   Cell Reports

Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure

(2014) Jakob D Wikstrom et al.   EMBO JOURNAL

Mineralocorticoid receptor antagonism induces browning of white adipose tissue through impairment of autophagy and prevents adipocyte dysfunction in high-fat-diet-fed mice

(2014) Andrea Armani et al.   FASEB JOURNAL

Ultrastructural analysis of autophagosome organization using mammalian autophagy-deficient cells

(2014) C. Kishi-Itakura et al.   JOURNAL OF CELL SCIENCE

SIRT1 and other sirtuins in metabolism

(2014) Hung-Chun Chang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity

(2014) Lindsay E. Wu et al.   Molecular Metabolism

Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number

(2012) Christopher T. Campbell et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Lipolytic Products Activate Peroxisome Proliferator-activated Receptor (PPAR) α and δ in Brown Adipocytes to Match Fatty Acid Oxidation with Supply

(2012) Emilio P. Mottillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Programming human pluripotent stem cells into white and brown adipocytes

(2012) Tim Ahfeldt et al.   NATURE CELL BIOLOGY

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes

(2011) Youngil Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Assessing mitochondrial dysfunction in cells

(2011) Martin D. Brand et al.   BIOCHEMICAL JOURNAL

Desnutrin/ATGL Is Regulated by AMPK and Is Required for a Brown Adipose Phenotype

(2011) Maryam Ahmadian et al.   Cell Metabolism

Phosphodiesterase type 5 (PDE5) in the adipocyte: a novel player in fat metabolism?

(2011) Andrea Armani et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Cellular models for understanding adipogenesis, adipose dysfunction, and obesity

(2010) Andrea Armani et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

(2010) Patrick Seale et al.   JOURNAL OF CLINICAL INVESTIGATION

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity

(2009) M. Saito et al.   DIABETES

Transcriptional control of brown adipocyte development and physiological function--of mice and men

(2009) P. Seale et al.   GENES & DEVELOPMENT

Autophagy regulates adipose mass and differentiation in mice

(2009) Rajat Singh et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis

(2009) Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Smooth muscle cells, dendritic cells and mast cells are sources of TNFalpha and nitric oxide in human carotid artery atherosclerosis

(2008) Stefano Bacci et al.   THROMBOSIS RESEARCH