Article
Agriculture, Dairy & Animal Science
Yingying Qiao, Changzhong Liu, Yongpeng Guo, Wei Zhang, Weibing Guo, Kyselov Oleksandr, Zhixiang Wang
Summary: This study investigated the effects of dietary supplementation of polysaccharides derived from Astragalus membranaceus and Glycyrrhiza uralensis on growth performance, intestinal health, and gut microbiota composition in broilers. The results showed that both polysaccharides improved growth performance, enhanced immune function, and modulated gut microbiota in broilers.
Article
Environmental Sciences
Yu Liu, Junming Deng, Beiping Tan, Shiwei Xie, Wei Zhang
Summary: This study evaluated the effects of different types of non-starch polysaccharides (NSPs) on growth performance, digestive enzyme activity, antioxidant capacity, and intestinal flora of juvenile GIFT tilapia. The results showed that dietary supplementation with soluble NSPs significantly increased certain enzyme activity and decreased antioxidant capacity, while dietary supplementation with insoluble NSPs had limited effect. The abundance of certain bacteria in the intestine was also affected by NSP supplementation.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Fisheries
Fei Shi, Zhijie Lu, Minxuan Yang, Feng Li, Fanbin Zhan, Lijuan Zhao, Yanan Li, Qingqing Li, Jiangtao Li, Jun Li, Li Lin, Zhendong Qin
Summary: The study showed that APS can modulate the intestinal microbiota and activate the immune response to protect grass carp from bacterial infection.
Article
Immunology
Fangmei Zhou, Yan Lu, Tong Sun, Ling Sun, Bixu Wang, Jingjing Lu, Zhimin Li, Bingqi Zhu, Shigao Huang, Zhishan Ding
Summary: The study demonstrates that Tetrastigma hemsleyanum polysaccharides (THP) can enhance antitumor effects, regulate gut microbiota, and improve immunosuppression induced by antitumor drugs.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Wei Yu, Yukai Yang, Qicun Zhou, Xiaolin Huang, Zhong Huang, Tao Li, Qiaer Wu, Chuanpeng Zhou, Zhenhua Ma, Heizhao Lin
Summary: This study demonstrates that the supplementation of Astragalus polysaccharides (APS) can have beneficial effects on the growth, health, and resistance to Vibrio harveyi of Asian seabass. APS supplementation at 0.10% to 0.20% significantly improved the growth performance, digestive enzyme activity, and intestinal health of Asian seabass. Furthermore, APS supplementation enhanced the antioxidant capacity and immune function of the fish. However, a higher concentration of APS (0.20%) had adverse effects on the growth and immune response of Asian seabass.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Fisheries
Milena Souza dos Santos Sanchez, Mariana Lins-Rodrigues, Jhonis Ernzen Pessini, Leonardo Jose Gil Barcellos, Fabio Bittencourt, Wilson Rogerio Boscolo, Altevir Signor
Summary: This study showed that the optimal dietary inclusion of betaine at 0.50 g kg(-1) improved growth performance in Nile tilapia by reducing lipid peroxidation. The betaine supplementation also affected the gut structure and blood glucose levels in fish.
AQUACULTURE NUTRITION
(2021)
Article
Microbiology
Ke Ming, Shen Zhuang, Ning Ma, Sha Nan, Qiuhua Li, Mingxing Ding, Yi Ding
Summary: Astragalus polysaccharides (APS) have preventive effects on inflammatory lung injury by improving lung tissue pathology, reducing neutrophil infiltration, inhibiting inflammation, and altering intestinal microbiota composition leading to increased levels of short-chain fatty acids (SCFAs) in the serum.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Fisheries
Alfredo Ruben Palomino Ramos, Daniel Abreu Vasconcelos Campelo, Cristiana Leonor da Silva Carneiro, Jener Alexandre Sampaio Zuanon, Sergio Luis Pinto da Matta, Wilson Massamitu Furuya, Ana Lucia Salaro
Summary: This study investigated the effects of different levels of L-glutamine supplementation on the growth performance and intestinal morphology of juvenile giant trahira. The optimal supplementation levels for maximizing growth performance and intestinal histomorphometry were found to be between 4.83 and 5.42 g/kg.
Article
Biochemistry & Molecular Biology
Shaojie Zhang, Lijun An, Zhengguo Li, Xuelian Wang, Honglin Wang, Lijuan Shi, Jiahe Bao, Xiaozhong Lan, Erhao Zhang, Namrita Lall, Anna-Mari Reid, Yuhao Li, Da-Qing Jin, Jing Xu, Yuanqiang Guo
Summary: In this study, an immunological arabinan, LCP70-2A, was isolated from Ligusticum chuanxiong for the first time. Physicochemical characterization revealed its homogeneous polysaccharide nature and potential as an immunological enhancement supplement by activating macrophages and promoting the secretion of immunoregulatory factors.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Physiology
Jingru Yang, Shengjie Zhou, Zhengyi Fu, Bo Xiao, Minghao Li, Gang Yu, Zhenhua Ma, Humin Zong
Summary: This study evaluated the effects of fermented Astragalus membranaceus on the liver and intestinal health of tiger grouper. The results showed that adding fermented Astragalus membranaceus to the feed improved liver health, regulated intestinal microbiota, and the optimal addition ratio was 1%-2%.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Pharmacology & Pharmacy
Wei Zheng, Tao Huang, Qi-Zhen Tang, Shi Li, Jie Qin, Feng Chen
Summary: Astragalus polysaccharide extract (APS) has been shown to significantly reduce blood pressure in hypertensive mice, reduce inflammation and renal fibrosis, and improve renal function. In addition, APS administration can alleviate the increase in serum creatinine, urea nitrogen, and uric acid levels.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Gaifeng Hou, Wei Peng, Liangkai Wei, Rui Li, Xingguo Huang, Yulong Yin
Summary: Probiotics or Achyranthes bidentata polysaccharides, either used alone or in combination (P-ABPS), have shown to improve piglets' growth performance by promoting intestinal nutrient digestion and absorption, as well as enhancing immune function. The combined supplement had a greater positive effect compared to the independent supplement, and it has the potential to serve as an alternative to in-feed antibiotics in piglet diets.
Review
Food Science & Technology
Kun Yang, Jing Chen, Jianping Chen, Zhuo Wang, Bingbing Song, Rui Li, Saiyi Zhong, Kit-Leong Cheong
Summary: A disorder of the immune system is the fundamental cause of cancer. Polysaccharides can regulate immune function and inhibit tumor growth by stimulating the immune system, increasing immune cell proliferation, and promoting cytokine secretion.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Article
Fisheries
Hong-Tao Shi, Sheng-Zhen Zhao, Kun-Li Wang, Ming-Xia Fan, Ying-Qian Han, Huan-Ling Wang
Summary: The study revealed that Astragalus Membranaceus and Lactobacillus p/antarum-fermented Astragalus Membranaceus significantly improved growth performance in common carp and had a major impact on intestinal microbiota and metabolism. Lactobacillus p/antarum-fermented Astragalus Membranaceus demonstrated superior beneficial metabolic effects in fish.
AQUACULTURE REPORTS
(2022)
Article
Nanoscience & Nanotechnology
Bing Yang, Xiaochun Wu, Jingqi Zeng, Jinjing Song, Tianhao Qi, Yanjun Yang, Dingkun Liu, Yulin Mo, Miao He, Liang Feng, Xiaobin Jia
Summary: This study investigated the potential of natural polysaccharides as carriers to improve the biopharmaceutical properties of active components. It was found that natural polysaccharides can self-assemble into aggregates and form complexes with the active components, thereby enhancing their stability, solubility, permeability, and absorption in the gastrointestinal tract.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2023)
Article
Biology
Naveed Akhtar, Muhammad Fiaz Khan, Sadia Tabassum, Eman Zahran
Summary: This study evaluated the adverse effects of atrazine on snow trout, showing significant changes in hematological, biochemical parameters, and genotoxicity. Exposure to atrazine resulted in alterations in blood parameters, as well as DNA damage, indicating potential toxicity in the tested fish species.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Article
Fisheries
Eman Zahran, Engy Risha, Awad Rizk
Summary: The study found that propofol has longer induction and anesthesia duration compared to eugenol in fish anesthesia, while also having a faster recovery rate. In terms of hematological indices, the propofol group showed a transient increase compared to the eugenol group. However, there were no significant changes in other indicators such as leukocytic counts between the two groups. During anesthesia, both propofol and eugenol groups showed a temporary increase in glucose and cortisol levels, which returned to baseline levels during the recovery period.
Article
Biology
Dina M. Aboraya, Ayman El Baz, Engy F. Risha, Fatma M. Abdelhamid
Summary: This study evaluates the hepatoprotective effect of hesperidin against cisplatin-induced toxicity. The results demonstrate that hesperidin can improve the hematological, biochemical, molecular, and histopathological alterations caused by cisplatin through its antioxidant, anti-inflammatory, and anti-apoptotic properties.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2022)
Article
Fisheries
Engy Risha, Fatma Ahmed, Asmaa A. Khaled, Ferdaus Mohd Altaf Hossain, Naveed Akhtar, Eman Zahran
Summary: Dietary supplementation with betaine and chromium picolinate can enhance the immune parameters and antioxidative activity in O. niloticus, with the combination of the two additives showing the most pronounced effects.
AQUACULTURE RESEARCH
(2022)
Article
Integrative & Complementary Medicine
Doha Reda, Gehad E. Elshopakey, Hebatallah A. Mahgoub, Engy F. Risha, Anmar A. Khan, Bodour S. Rajab, Mohamed E. El-Boshy, Fatma M. Abdelhamid
Summary: Resveratrol has been found to have protective effects against metabolic alterations associated with metabolic syndrome, including reducing liver steatosis, oxidative stress, and inflammatory state, improving lipid profile, and insulin sensitivity.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2022)
Article
Fisheries
Samar A. El Gamal, Rawia Saad Adawy, Viola Hassan Zaki, Ahmed Abdelkhalek, Eman Zahran
Summary: This study investigated the outbreaks of saprolegniasis in Nile tilapia farms in northern Egypt and its connection to water quality parameters. The study also examined the genetic diversity of saprolegnia isolates from different farms and the resulting ultrastructural lesions. Results showed significant variations in the prevalence of saprolegniasis among different regions and months. The genetic analysis revealed the presence of genetic diversity among the isolates.
Article
Fisheries
Mona Abd El-Khalek Salem, Rawia Saad Adawy, Viola Hassan Zaki, Eman Zahran
Summary: This study evaluated the potential roles of incorporating Nannochloropsis oculata into the diet of Nile Tilapia Oreochromis niloticus. The results showed that the addition of N. oculata stimulated fish body weight and improved feed conversion efficiency. Furthermore, N. oculata had positive effects on fish health and immune system.
JOURNAL OF AQUATIC ANIMAL HEALTH
(2022)
Article
Biochemistry & Molecular Biology
Aya Megahed, Hossam Gadalla, Fatma M. Abdelhamid, Samah J. Almehmadi, Anmar A. Khan, Talat A. Albukhari, Engy F. Risha
Summary: Vitamin D-3 (VD3) plays a beneficial role in overcoming extensive liver fibrosis caused by thioacetamide (TAA) exposure. VD3 treatment improves liver function and reduces liver fibrosis measures. It decreases liver enzyme levels, bilirubin, cholesterol, and triglyceride levels, while increasing glucose and 25[OH]D-3 levels. VD3 also reduces oxidative stress and fibrosis-related gene expressions.
Article
Veterinary Sciences
Eman Zahran, Samia Elbahnaswy, Fatma Ahmed, Iman Ibrahim, Asmaa A. Khaled, Elsayed A. Eldessouki
Summary: The marine microalga Nannochloropsis oculata has great potential for nutraceutical and functional food industry applications due to its bioactive compounds and high omega-3 polyunsaturated fatty acid content. In this study, Nile tilapia fed diets supplemented with N. oculata showed improved growth performance, proximate composition, lipid profile, and gene expression pattern related to lipid metabolism and immune response. Histopathological examination confirmed the benefits and safety of N. oculata dietary inclusion. Overall, N. oculata is a promising nutraceutical for enhancing fish health and sustainability in aquaculture production.
BMC VETERINARY RESEARCH
(2023)
Article
Pharmacology & Pharmacy
Doha Reda, Gehad E. Elshopakey, Talat A. Albukhari, Samah J. Almehmadi, Bassem Refaat, Engy F. Risha, Hebatallah A. Mahgoub, Mohamed E. El-Boshy, Fatma M. Abdelhamid
Summary: This study aimed to explore the protective effect of vitamin D3 (VitD) against nonalcoholic fatty liver disease (NAFLD). The results showed that VitD treatment improved the biochemical parameters, hepatic oxidative stress, and inflammation in NAFLD rats, reducing fat accumulation and inflammatory response.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Lubna A. H. Mansour, Gehad E. Elshopakey, Fatma M. Abdelhamid, Talat A. Albukhari, Samah J. Almehmadi, Bassem Refaat, Mohamed El-Boshy, Engy F. Risha
Summary: Naringenin (NRG), a naturally occurring flavonoid found in citrus species and tomatoes, has various biological activities including antioxidant, antitumor, antiviral, antibacterial, anti-inflammatory, antiadipogenic, and cardioprotective effects. This study investigated the protective role of NRG against liver and brain toxicity induced by lead acetate in rats. The findings suggest that NRG has potential hepato- and neuroprotective effects against lead acetate toxicity.
Article
Biochemistry & Molecular Biology
Eman Zahran, Fatma Ahmed, Zeinab Hassan, Iman Ibrahim, Asmaa A. Khaled, Dusan Palic, Mahmoud G. El Sebaei
Summary: The potential ameliorative effect of a dietary immune modulator, Nannochloropsis oculata microalga, on the toxic effects of mercury chloride (HgCl2) in Nile tilapia was evaluated. Supplementation with N. oculata was found to alleviate HgCl2-induced toxicity and could be a potential therapeutic/preventive agent for environmental heavy metal pollution in aquatic habitats.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
