Article
Fisheries
Chao Peng, Chao Zhao, Peng-Fei Wang, Lu-Lu Yan, Si-Gang Fan, Li-Hua Qiu
Summary: The research identified a novel TRIM32 homolog, PmTRIM32, in Penaeus monodon, which was significantly upregulated by rapamycin stimulation and WSSV infection. PmTRIM32 was found to restrict WSSV replication, positively regulate autophagy and NF-kappa B pathway, and interact with WSSV envelope protein for ubiquitination.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2021)
Article
Zoology
Abu Salman Talukder, Nusrat Jahan Punom, Md Mostavi Enan Eshik, Mst Khadiza Begum, H. M. Rakibul Islam, Zakir Hossain, Mohammad Shamsur Rahman
Summary: White spot disease has caused significant economic losses in the shrimp farming industry in Bangladesh over the past two decades. The study conducted in the southwest region of Bangladesh in 2018 identified nine significant risk factors for WSD, confirmed WSSV infection, and found a high prevalence of WSSV in the Khulna region with strains identical to those in India. The relationships between risk factors, disease prevalence and severity, and WSSV strains could greatly impact WSD management.
JOURNAL OF INVERTEBRATE PATHOLOGY
(2021)
Article
Fisheries
Chao Zhao, Chao Peng, Pengfei Wang, Bo Zhang, Lulu Yan, Chun-Lin Wang, Lihua Qiu
Summary: In this study, a novel TRIM37 homolog called PmTRIM37 was identified, which plays important roles in regulating innate immune processes, particularly antiviral and proinflammatory cytokine responses. PmTRIM37 is highly expressed in immune-related tissues and its expression is up-regulated after white spot syndrome virus (WSSV) infection. Knockdown of PmTRIM37 promotes WSSV replication and VP28 expression, suggesting its negative role in WSSV infection. Furthermore, PmTRIM37 positively regulates the NF-κB pathway and Antimicrobial peptides (AMP) expression during WSSV infection.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
Yaqun Zhang, Na Yao, Chuantao Zhang, Xiangshan Sun, Jingxian Huang, Bingran Zhao, Hengde Li
Summary: This study identified differentially expressed mRNAs and lncRNAs in the hepatopancreas of Penaeus japonicas in response to white spot syndrome virus (WSSV) infection. Functional enrichment analysis revealed that these differentially expressed genes were related to immune response and viral infectivity. Some lncRNAs were induced by WSSV infection and may be involved in regulating immune processes.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Multidisciplinary Sciences
Mostafa Rakhshaninejad, Liping Zheng, Hans Nauwynck
Summary: This study found that Penaeus vannamei shrimp infected with White spot syndrome virus (WSSV) use behavioral fever to increase their body temperature, inhibit virus replication, and prevent infection and mortality.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Pasunee Laohawutthichai, Thapanan Jatuyosporn, Premruethai Supungul, Anchalee Tassanakajon, Kuakarun Krusong
Summary: This research investigates the effects of PmDOME and PmSTAT silencing on immune-related gene expressions in shrimp hemocytes during WSSV infection. It found that the silencing of PmDOME and PmSTAT significantly impacted the expression levels of multiple immune-related genes and reduced WSSV replication and mortality. The study suggests that suppression of the JAK/STAT signaling pathway may delay WSSV-related mortality by activating immune responses.
SCIENTIFIC REPORTS
(2023)
Article
Fisheries
Annies Joseph, Rosamma Philip
Summary: This study aimed to determine the influence of copper on the physiological and immunological responses of Penaeus monodon to white spot syndrome virus (WSSV) infection. The results showed that exposure to 0.1 mg/l copper concentration enhanced the immune response and resistance to WSSV infection in the shrimp, resulting in higher survival. However, exposure to 0.2 and 0.3 mg/l copper concentrations increased susceptibility to WSSV infection, leading to a decrease in biochemical/immune variables.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
Chorong Lee, Hye Jin Jeon, Bumkeun Kim, Sangsu Suh, Patharapol Piamsomboon, Ji Hyung Kim, Jee Eun Han
Summary: This study investigated the presence of white spot syndrome virus (WSSV) and decapod hepanhamaparvovirus (DHPV) in shrimp, pond water, crab, and live food samples collected from farms in three provinces of Korea. The results showed that all shrimp samples were positive for DHPV, with 41 samples also testing positive for WSSV. Sequencing and analysis revealed that the DHPV samples belonged to a novel genotype. Additionally, novel genotypes of DHPV were found in squid, polychaeta, and crab samples. The co-infection of WSSV and DHPV was observed in shrimp, pond water, and crab samples, and histopathological analysis confirmed the presence of both viruses in shrimp.
JOURNAL OF THE WORLD AQUACULTURE SOCIETY
(2023)
Article
Fisheries
Warumporn Yingsunthonwattana, Wisarut Junprung, Premruethai Supungul, Anchalee Tassanakajon
Summary: The study investigated the involvement of Litopenaeus vannamei (Lv) HSP90 in white spot syndrome virus (WSSV) infections. Silencing LvHSP90 resulted in reduced shrimp mortality and viral replication, but also induced apoptosis and potentially led to shrimp death.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Immunology
Yashdeep Phanse, Supraja Puttamreddy, Duan Loy, Julia Vela Ramirez, Kathleen A. Ross, Ignacio Alvarez-Castro, Mark Mogler, Scott Broderick, Krishna Rajan, Balaji Narasimhan, Lyric C. Bartholomay
Summary: In the past 15 years, crustacean fisheries have suffered significant economic losses due to viral diseases. No effective measures are available to prevent or control these outbreaks. However, a double-stranded RNA-based nanovaccine shows promise for controlling infectious diseases in aquaculture.
Article
Fisheries
Ngoc Tuan Tran, Huifen Liang, Jinkun Li, Taoqiu Deng, Md Akibul Hasan Bakky, Ming Zhang, Shengkang Li
Summary: Innate immunity is crucial for protecting crustaceans against pathogens, especially the serious white spot syndrome virus (WSSV). Understanding how hosts respond to WSSV infection is essential for prevention and control. This review summarizes the involvement of signaling pathways and cellular activities in the immune response of crustaceans during WSSV infection, providing important insights into host-pathogen interaction and potential strategies for enhancing immune defense.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
M. G. Pratapa, Saurav Kumar, M. K. Bedekar, H. Sanath Kumar, K. V. Rajendran
Summary: This study investigates the susceptibility of mud crabs to white spot syndrome virus (WSSV) compared to shrimp. The results show that mud crabs have relatively lower mortality rates when infected with WSSV compared to shrimp. The viral load in different tissues also varies between shrimp and mud crabs.
Article
Multidisciplinary Sciences
Thapanan Jatuyosporn, Pasunee Laohawutthichai, Juan Pablo Ochoa Romo, Luigui Gallardo-Becerra, Filiberto Sanchez Lopez, Anchalee Tassanakajon, Adrian Ochoa-Leyva, Kuakarun Krusong
Summary: The gut microbiome is important for the immune system of both invertebrates and vertebrates. Pre and pro-biotics can enhance the shrimp immune system by increasing the activity of certain enzymes. Changes in the host immune system during viral infection can affect the gut microbiome and potentially lead to other infections.
SCIENTIFIC REPORTS
(2023)
Article
Biochemistry & Molecular Biology
Vipul Panchal, Sushil Kumar, Shaikh Nausad Hossain, Dileep Vasudevan
Summary: This study presents the first thymidylate synthase (TS) structure from a crustacean virus, highlighting its distinction from shrimp and other TS structures, providing important insights for further research.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Fisheries
Wang-Jing Liu, Yun-Shiang Chang, Kou-Chun Tseng, Meng-Hua Yu
Summary: White spot syndrome virus (WSSV) is a prominent pathogen in shrimp farming worldwide. However, there is currently no effective treatment for this virus. In this study, the antiviral properties of bovine lactoferrin (bLF) against WSSV were investigated, and it was found that bLF treatment significantly reduced shrimp mortalities caused by WSSV infection. The ability of bLF to bind to both host cells and WSSV virions suggests its potential as an anti-WSSV agent in shrimp culture, and the identified interaction proteins may play a role in WSSV infection.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2023)
Article
Multidisciplinary Sciences
Huei-Mien Ke, Anuphap Prachumwat, Chun-Ping Yu, Yi-Ting Yang, Sutitcha Promsri, Kuan-Fu Liu, Chu-Fang Lo, Mei-Yeh Jade Lu, Mei-Chin Lai, Isheng J. Tsai, Wen-Hsiung Li
SCIENTIFIC REPORTS
(2017)
Article
Immunology
Jiun-Yan Huang, Shih-Ting Kang, I-Tung Chen, Li-Kwan Chang, Shih-Shun Lin, Guang-Hsiung Kou, Chia-Ying Chu, Chu-Fang Lo
FRONTIERS IN IMMUNOLOGY
(2017)
Article
Cell Biology
Tze Hann Ng, Chia-Wei Lu, Shih-Shun Lin, Che-Chih Chang, Loc H. Tran, Wen-Chi Chang, Chu-Fang Lo, Han-Ching Wang
CELLULAR MICROBIOLOGY
(2018)
Article
Food Science & Technology
Shin-Jen Lin, Yi-Fan Chen, Kai-Cheng Hsu, Yun-Ling Chen, Tzu-Ping Ko, Chu-Fang Lo, Han-Ching Wang, Hao-Ching Wang
Article
Multidisciplinary Sciences
Huai-Ting Huang, Han-Jia Lin, Hui-Ju Huang, Chih-Ching Huang, John Han-You Lin, Li-Li Chen
SCIENTIFIC REPORTS
(2020)
Article
Virology
Po-Yu Huang, Han-Chia Hsiao, Szu-Wen Wang, Shao-Fu Lo, Ming-Wei Lu, Li-Li Chen
Article
Agriculture, Dairy & Animal Science
Chia-Huan Ma, Po-Yu Huang, Yung-Cheng Chang, Yen-Ju Pan, Mohamad Nor Azra, Li-Li Chen, Te-Hua Hsu
Summary: Reducing fighting behavior is crucial in lobster and crab aquaculture to enhance survival rates. Providing shelter and co-culturing with live prey can significantly improve the survival of juvenile lobsters and crabs, with live prey also serving as an additional income source during harvest season.
Article
Agriculture, Dairy & Animal Science
Po-Tsang Lee, Jing Huang, Chin-Yi Huang, Zi-Xuan Liu, Han-Yang Yeh, Huai-Ting Huang, Li-Li Chen, Fan-Hua Nan, Meng-Chou Lee
Summary: The study demonstrates that phycoerythrin from Colaconema sp. can act as an immunomodulator in whiteleg shrimp, enhancing immune gene expression and innate immune parameters to increase survival rates when challenged with viruses or bacteria.
Article
Biology
Po-Yu Huang, Yi-Hsuan Huang, Jiann-Horng Leu, Li-Li Chen
Summary: The study demonstrated that maggots can effectively deliver target proteins to the shrimp intestine, where they are absorbed. Maggots also increased the total haemocyte count and phenoloxidase activity of the shrimp, and induced the expression of penaeidins 2. In the WSSV challenge, the survival rate of shrimp fed with rVP24 protein using maggots was approximately 43%. This indicates that maggots can serve as effective oral delivery systems for aquatic products and provide a new method for aquatic vaccine delivery systems.
Article
Biotechnology & Applied Microbiology
Shao-Chieh Yen, Ju-Yi Mao, Hung-Yun Lin, Huai-Ting Huang, Scott G. Harroun, Amit Nain, Huan-Tsung Chang, Han-You Lin, Li-Li Chen, Chih-Ching Huang, Han-Jia Lin
Summary: The study introduces a novel carbon-based nanomaterial, DAO/DEX-CNGs, which show effective antibacterial properties against Vibrio parahaemolyticus responsible for AHPND, including multi-drug resistant strains, offering protection for shrimp against bacterial invasion.
JOURNAL OF NANOBIOTECHNOLOGY
(2021)
Article
Virology
Jeff Chia-Kai Hsu, Huai-Ting Huang, Han-Jia Lin, Hsin-Yiu Chou, Po-Yu Huang, Anuphap Prachumwat, Li-Li Chen
Summary: This study conducted a field feeding trial in Kaohsiung, Taiwan, demonstrating for the first time that recombinant proteins from white spot syndrome virus (WSSV) can improve shrimp survival rates. These proteins can be used as an effective anti-virus biological agent in shrimp farms.
Article
Agriculture, Dairy & Animal Science
Yovita Permata Budi, Li-Chi Lin, Chang-Hsien Chung, Li-Li Chen, Yi-Fan Jiang
Summary: White spot syndrome virus is a lethal disease in shrimp culture systems. This study provides new structural information on the virus and contributes to the development of treatment or prevention strategies.
Article
Fisheries
Jeff Chia-Kai Hsu, Te-Ken Hsu, Jiji Kannan, Han-Ching Wang, Anchalee Tassanakajon, Li-Li Chen
Summary: This study tested the performance of a commercial WSSV rapid test kit and found that it was convenient, stable, sensitive, and specific. The sensitivity and specificity analysis showed the importance of this kit in diagnosing WSSV infection in shrimp farms.
Article
Biochemistry & Molecular Biology
Hui-Ju Huang, Sen-Lin Tang, Yuan-Chih Chang, Hao-Ching Wang, Tze Hann Ng, Rees F. Garmann, Yu-Wen Chen, Jiun-Yan Huang, Ramya Kumar, Sheng-Hsiung Chang, Shang-Rung Wu, Chih-Yu Chao, Kyoko Matoba, Iwasaki Kenji, William M. Gelbart, Tzu-Ping Ko, Hwei-Jiung (Andrew) Wang, Chu-Fang Lo, Li-Li Chen, Han-Ching Wang
Summary: Transmission electron microscopy (TEM) and cryogenic electron microscopy (Cryo-EM) techniques were used to study the morphology and pathogenesis of White spot syndrome virus (WSSV). The mature WSSV virions were found to have an oval shape without tail-like extensions. Two distinct ends, a portal cap, and a closed base, were observed in WSSV nucleocapsids. A C14 symmetric structure of the WSSV nucleocapsid was proposed based on Cryo-EM map. Immunoelectron microscopy (IEM) revealed a ring-like architecture formed by VP664 proteins, the main components of the 14 assembly units, in WSSV. Furthermore, a unique helical dissociation process of WSSV nucleocapsids was observed. Based on these findings, a novel morphogenetic pathway of WSSV was proposed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Ramya Kumar, Che-Chih Chang, Tze Hann Ng, Jiun-Yan Ding, Ta-Chien Tseng, Chu-Fang Lo, Han-Ching Wang
GENOME ANNOUNCEMENTS
(2018)