Probing the interaction of a quercetin bioconjugate with Bcl-2 in living human cancer cells with in-cell NMR spectroscopy

Rational design and structure–activity relationship studies of quercetin–amino acid hybrids targeting the anti-apoptotic protein Bcl-xL

(2017) Tahsin F. Kellici et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Application of Bioactive Quercetin in Oncotherapy: From Nutrition to Nanomedicine

(2016) Ju-Suk Nam et al.   MOLECULES

Structural disorder of monomeric α-synuclein persists in mammalian cells

(2016) Francois-Xavier Theillet et al.   NATURE

Characterization of proteins by in-cell NMR spectroscopy in cultured mammalian cells

(2016) Letizia Barbieri et al.   Nature Protocols

Structural evidence forArabidopsisglutathione transferaseAtGSTF2 functioning as a transporter of small organic ligands

(2016) Laziana Ahmad et al.   FEBS Open Bio

A Unique Tool for Cellular Structural Biology: In-cell NMR

(2015) Enrico Luchinat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The re-emergence of natural products for drug discovery in the genomics era

(2015) Alan L. Harvey et al.   NATURE REVIEWS DRUG DISCOVERY

Quinary structure modulates protein stability in cells

(2015) William B. Monteith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Binding of Bcl-2 Family Proteins by Quercetin Triggers Its Pro-Apoptotic Activity

(2014) Alexandra Primikyri et al.   ACS Chemical Biology

Real-Time Monitoring of New Delhi Metallo-β-Lactamase Activity in Living Bacterial Cells by1H NMR Spectroscopy

(2014) Junhe Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Live Cell NMR

(2014) Darón I. Freedberg et al.   Annual Review of Biophysics

Physicochemical Properties of Cells and Their Effects on Intrinsically Disordered Proteins (IDPs)

(2014) Francois-Xavier Theillet et al.   CHEMICAL REVIEWS

Biochemical and biological assessment of the inhibitory potency of extracts from vinification byproducts of Vitis vinifera extracts against glycogen phosphorylase

(2014) Anastassia L. Kantsadi et al.   FOOD AND CHEMICAL TOXICOLOGY

Multi-phosphorylation of the Intrinsically Disordered Unique Domain of c-Src Studied by In-Cell and Real-Time NMR Spectroscopy

(2013) Irene Amata et al.   CHEMBIOCHEM

Interaction of Bcl-2 with the Autophagy-related GABAAReceptor-associated Protein (GABARAP)

(2013) Peixiang Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pruning the ALS-Associated Protein SOD1 for in-Cell NMR

(2013) Jens Danielsson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In-cell NMR: an emerging approach for monitoring metal-related events in living cells

(2013) Hongyan Li et al.   Metallomics

Atomic-resolution monitoring of protein maturation in live human cells by NMR

(2013) Lucia Banci et al.   Nature Chemical Biology

Determination of the binding epitope of RGD-peptidomimetics to αvβ3 and αIIbβ3 integrin-rich intact cells by NMR and computational studies

(2013) Ileana Guzzetti et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Gel-Encapsulated Bioreactor System for NMR Studies of Protein-Protein Interactions in Living Mammalian Cells

(2012) Satoshi Kubo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

STD and trNOESY NMR Study of Receptor-Ligand Interactions in Living Cancer Cells

(2011) Donatella Potenza et al.   CHEMBIOCHEM

Saturation-Transfer Difference (STD) NMR: A Simple and Fast Method for Ligand Screening and Characterization of Protein Binding

(2011) Aldino Viegas et al.   JOURNAL OF CHEMICAL EDUCATION

Probing the Interaction of Cisplatin with the Human Copper Chaperone Atox1 by Solution and In-Cell NMR Spectroscopy

(2011) Fabio Arnesano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

2D TR-NOESY Experiments Interrogate and Rank Ligand-Receptor Interactions in Living Human Cancer Cells

(2010) Silvia Mari et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Quercetin and Cancer Chemoprevention

(2010) Lara Gibellini et al.   Evidence-based Complementary and Alternative Medicine

In-cell NMR spectroscopy

(2010) Andres Y. Maldonado et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Bcl-2 blocks 2-methoxyestradiol induced leukemia cell apoptosis by a p27Kip1-dependent G1/S cell cycle arrest in conjunction with NF-κB activation

(2009) Christina Batsi et al.   BIOCHEMICAL PHARMACOLOGY

Mitochondria accumulate large amounts of quercetin: prevention of mitochondrial damage and release upon oxidation of the extramitochondrial fraction of the flavonoid

(2009) Mara Fiorani et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

High-resolution multi-dimensional NMR spectroscopy of proteins in human cells

(2009) Kohsuke Inomata et al.   NATURE

In vitro solubility, stability and permeability of novel quercetin–amino acid conjugates

(2008) Mi Kyoung Kim et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Direct NMR Detection of the Binding of Functional Ligands to the Human Sweet Receptor, a Heterodimeric Family 3 GPCR

(2008) Fariba M. Assadi-Porter et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In situ observation of protein phosphorylation by high-resolution NMR spectroscopy

(2008) Philipp Selenko et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Metabolomics: back to basics

(2008) R. Verpoorte et al.   PHYTOCHEMISTRY REVIEWS

Three flavonoids targeting the β-hydroxyacyl-acyl carrier protein dehydratase fromHelicobacter pylori: Crystal structure characterization with enzymatic inhibition assay

(2008) Liang Zhang et al.   PROTEIN SCIENCE