Interaction of Bcl-2 with the Autophagy-related GABAAReceptor-associated Protein (GABARAP)

Removal of the BH4 Domain from Bcl-2 Protein Triggers an Autophagic Process that Impairs Tumor Growth

(2015) Daniela Trisciuoglio et al.   NEOPLASIA

Dual Role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation

(2014) Yongjie Wei et al.   Autophagy

Bcl-2 family members: Dual regulators of apoptosis and autophagy

(2014) Beth Levine et al.   Autophagy

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

(2013) Andrew J Souers et al.   NATURE MEDICINE

Modulation of Serines 17 and 24 in the LC3-interacting Region of Bnip3 Determines Pro-survival MitophagyversusApoptosis

(2012) Yanyan Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of Atg8 Activation by a Homodimeric E1, Atg7

(2011) Nobuo N. Noda et al.   MOLECULAR CELL

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

(2011) P. Wild et al.   SCIENCE

Downregulation of autophagy by Bcl-2 promotes MCF7 breast cancer cell growth independent of its inhibition of apoptosis

(2010) S Oh et al.   CELL DEATH AND DIFFERENTIATION

Preparation of a Functional GABARAP-Lipid Conjugate in Nanodiscs and its Investigation by Solution NMR Spectroscopy

(2010) Peixiang Ma et al.   CHEMBIOCHEM

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

(2010) Hilla Weidberg et al.   EMBO JOURNAL

Atg8-family interacting motif crucial for selective autophagy

(2010) Nobuo N. Noda et al.   FEBS LETTERS

Kinetics Comparisons of Mammalian Atg4 Homologues Indicate Selective Preferences toward Diverse Atg8 Substrates

(2010) Min Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nix directly binds to GABARAP: A possible crosstalk between apoptosis and autophagy

(2009) Melanie Schwarten et al.   Autophagy

The late stages of autophagy: how does the end begin?

(2009) T Noda et al.   CELL DEATH AND DIFFERENTIATION

The structure of Atg4B–LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy

(2009) Kenji Satoo et al.   EMBO JOURNAL

Nix is a selective autophagy receptor for mitochondrial clearance

(2009) Ivana Novak et al.   EMBO REPORTS

Structural framework of the GABARAP-calreticulin interface - implications for substrate binding to endoplasmic reticulum chaperones

(2009) Yvonne Thielmann et al.   FEBS Journal

Structure and potential function of γ-aminobutyrate type A receptor-associated protein

(2009) Jeannine Mohrlüder et al.   FEBS Journal

Structural characterization of GABARAP–ligand interactions

(2009) Yvonne Thielmann et al.   Molecular BioSystems

Phospho-Regulated SUMO Interaction Modules Connect the SUMO System to CK2 Signaling

(2009) Per Stehmeier et al.   MOLECULAR CELL

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

GABA Receptor Expression in Benign and Malignant Thyroid Tumors

(2009) Stephen S. Roberts et al.   PATHOLOGY & ONCOLOGY RESEARCH

Comparative modeling of human NSF reveals a possible binding mode of GABARAP and GATE-16

(2009) Yvonne Thielmann et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

An Indole‐Binding Site is a Major Determinant of the Ligand Specificity of the GABA Type A Receptor‐Associated Protein GABARAP

(2008) Yvonne Thielmann et al.   CHEMBIOCHEM

Ligand Binding Mode of GABAA Receptor-Associated Protein

(2008) Oliver H. Weiergräber et al.   JOURNAL OF MOLECULAR BIOLOGY

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE