Human small heat shock proteins: Protein interactomes of homo- and hetero-oligomeric complexes: An update

HspB8 and Bag3: A new chaperone complex targeting misfolded proteins to macroautophagy

(2014) Serena Carra et al.   Autophagy

Mutations of small heat shock proteins and human congenital diseases

(2013) P. N. Datskevich et al.   BIOCHEMISTRY-MOSCOW

Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation

(2013) Guillaume Wettstein et al.   FASEB JOURNAL

Protein interactomes of three stress inducible small heat shock proteins: HspB1, HspB5 and HspB8

(2013) André-Patrick Arrigo et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Structural and Functional Aspects of Hetero-oligomers Formed by the Small Heat Shock Proteins αB-Crystallin and HSP27

(2013) J. Andrew Aquilina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peptide aptamers: tools to negatively or positively modulate HSPB1(27) function

(2013) B. Gibert et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update

(2012) Daniel R. Ciocca et al.   ARCHIVES OF TOXICOLOGY

Targeting heat shock protein 27 (HspB1) interferes with bone metastasis and tumour formation in vivo

(2012) B Gibert et al.   BRITISH JOURNAL OF CANCER

A Census of Human Soluble Protein Complexes

(2012) Pierre C. Havugimana et al.   CELL

Downregulation of Hsp27 (HSPB1) in MCF-7 human breast cancer cells induces upregulation of PTEN

(2012) Niubys Cayado-Gutiérrez et al.   CELL STRESS & CHAPERONES

HspB1 Dynamic Phospho-Oligomeric Structure Dependent Interactome as Cancer Therapeutic Target

(2012) A.-P. Arrigo et al.   CURRENT MOLECULAR MEDICINE

αA- and αB-Crystallins Interact with Caspase-3 and Bax to Guard Mouse Lens Development

(2012) W.-F. Hu et al.   CURRENT MOLECULAR MEDICINE

Inhibiting HSP90 to Treat Cancer: A Strategy in Evolution

(2012) L. Whitesell et al.   CURRENT MOLECULAR MEDICINE

The Role of Intrinsically Disordered Regions in the Structure and Functioning of Small Heat Shock Proteins

(2012) Maria V. Sudnitsyna et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

The family of mammalian small heat shock proteins (HSPBs): Implications in protein deposit diseases and motor neuropathies

(2012) Alessandra Boncoraglio et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Commentary on paper: Small heat shock proteins and the cytoskeleton: An essential interplay for cell integrity? (Wettstein et al.)

(2012) Alim S. Seit-Nebi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Therapeutic Effects of Systemic Administration of Chaperone αB-Crystallin Associated with Binding Proinflammatory Plasma Proteins

(2012) Jonathan B. Rothbard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small heat shock proteins target mutant cystic fibrosis transmembrane conductance regulator for degradation via a small ubiquitin-like modifier–dependent pathway

(2012) Annette Ahner et al.   MOLECULAR BIOLOGY OF THE CELL

Dynamic Protein-Protein Interaction Wiring of the Human Spliceosome

(2012) Anna Hegele et al.   MOLECULAR CELL

Knock Down of Heat Shock Protein 27 (HspB1) Induces Degradation of Several Putative Client Proteins

(2012) Benjamin Gibert et al.   PLoS One

HspB2/Myotonic Dystrophy Protein Kinase Binding Protein (MKBP) as a Novel Molecular Chaperone: Structural and Functional Aspects

(2012) Sankaralingam Prabhu et al.   PLoS One

The Chaperone-like Activity of Rat HspB8/Hsp22 and Dynamic Molecular Transition Related to Oligomeric Architectures In Vitro

(2012) Zehong Yang et al.   PROTEIN AND PEPTIDE LETTERS

Biochemical characterization of small heat shock protein HspB8 (Hsp22)–Bag3 interaction

(2011) Anton A. Shemetov et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

αB-crystallin, a small heat shock protein, modulates NF-κB activity in a phosphorylation-dependent manner and protects muscle myoblasts from TNF-α induced cytotoxicity

(2011) Amit S. Adhikari et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Structural and functional specificity of small heat shock protein HspB1 and HspB4, two cellular partners of HspB5: Role of the in vitro hetero-complex formation in chaperone activity

(2011) Fériel Skouri-Panet et al.   BIOCHIMIE

Binding of the Molecular Chaperone αB-Crystallin to Aβ Amyloid Fibrils Inhibits Fibril Elongation

(2011) Sarah L. Shammas et al.   BIOPHYSICAL JOURNAL

Hsp27 silencing coordinately inhibits proliferation and promotes Fas-induced apoptosis by regulating the PEA-15 molecular switch

(2011) N Hayashi et al.   CELL DEATH AND DIFFERENTIATION

Heterooligomeric complexes of human small heat shock proteins

(2011) Evgeny V. Mymrikov et al.   CELL STRESS & CHAPERONES

Ubiquitination of heat shock protein 27 is mediated by its interaction with Smad ubiquitination regulatory factor 2 in A549 cells

(2011) Yong Sun et al.   EXPERIMENTAL LUNG RESEARCH

Chaperone Hsp27 Modulates AUF1 Proteolysis and AU-Rich Element-Mediated mRNA Degradation

(2011) A. M. Knapinska et al.   MOLECULAR AND CELLULAR BIOLOGY

Toward an understanding of the protein interaction network of the human liver

(2011) J. Wang et al.   Molecular Systems Biology

XPORT-Dependent Transport of TRP and Rhodopsin

(2011) Erica E. Rosenbaum et al.   NEURON

Large Potentials of Small Heat Shock Proteins

(2011) Evgeny V. Mymrikov et al.   PHYSIOLOGICAL REVIEWS

HSPB1, HSPB6, HSPB7 and HSPB8 Protect against RhoA GTPase-Induced Remodeling in Tachypaced Atrial Myocytes

(2011) Lei Ke et al.   PLoS One

An Interaction Network Predicted from Public Data as a Discovery Tool: Application to the Hsp90 Molecular Chaperone Machine

(2011) Pablo C. Echeverría et al.   PLoS One

Inhibition of α-synuclein aggregation by small heat shock proteins

(2011) Ilona B. Bruinsma et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Small heat shock proteins and α-crystallins: dynamic proteins with flexible functions

(2011) Eman Basha et al.   TRENDS IN BIOCHEMICAL SCIENCES

Phosphomimicking mutations of human 14-3-3ζ affect its interaction with tau protein and small heat shock protein HspB6

(2010) Nikolai N. Sluchanko et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

HSP27 controls GATA-1 protein level during erythroid cell differentiation

(2010) A. de Thonel et al.   BLOOD

 B-crystallin: a novel VEGF chaperone

(2010) B. A. Kerr et al.   BLOOD

Hsp27 Promotes Insulin-Like Growth Factor-I Survival Signaling in Prostate Cancer via p90Rsk-Dependent Phosphorylation and Inactivation of BAD

(2010) A. Zoubeidi et al.   CANCER RESEARCH

Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3)

(2010) Xiankui Sun et al.   CELL STRESS & CHAPERONES

Expression and Functions of Heat Shock Proteins in the Normal and Pathological Mammalian Eye

(2010) A.-P. Arrigo et al.   CURRENT MOLECULAR MEDICINE

Small Heat Shock Proteins and Protein-Misfolding Diseases

(2010) Ewa Laskowska et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Repeated-dose toxicity of HSP27-binding heptapeptide in mice

(2010) Hae-June Lee et al.   DRUG AND CHEMICAL TOXICOLOGY

ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair

(2010) Claudia Cosentino et al.   EMBO JOURNAL

Dynamic processes that reflect anti-apoptotic strategies set up by HspB1 (Hsp27)

(2010) Catherine Paul et al.   EXPERIMENTAL CELL RESEARCH

HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones

(2010) Michel J. Vos et al.   HUMAN MOLECULAR GENETICS

The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)

(2010) Valeria Crippa et al.   HUMAN MOLECULAR GENETICS

Oligomers of Mutant Glial Fibrillary Acidic Protein (GFAP) Inhibit the Proteasome System in Alexander Disease Astrocytes, and the Small Heat Shock Protein αB-Crystallin Reverses the Inhibition

(2010) Guomei Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of Hsp27 with Native Phosphorylase Kinase under Crowding Conditions

(2010) Natalia A. Chebotareva et al.   MACROMOLECULAR BIOSCIENCE

Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E

(2010) C Andrieu et al.   ONCOGENE

Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation

(2010) A. L. Robertson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The stress-inducible HspB8-Bag3 complex induces the eIF2α kinase pathway: Implications for protein quality control and viral factory degradation?

(2009) Serena Carra   Autophagy

Identification of the key structural motifs involved in HspB8/HspB6–Bag3 interaction

(2009) Margit Fuchs et al.   BIOCHEMICAL JOURNAL

Interactions between Small Heat Shock Protein α-Crystallin and Galectin-Related Interfiber Protein (GRIFIN) in the Ocular Lens

(2009) Kelly A. Barton et al.   BIOCHEMISTRY

Versatility of the small heat shock protein HSPB6 (Hsp20)

(2009) Alim S. Seit-Nebi et al.   CELL STRESS & CHAPERONES

Mechanism of Suppression of Protein Aggregation by α-Crystallin

(2009) Kira Markossian et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Small Heat-Shock Proteins HSPB2 and HSPB3 Form Well-defined Heterooligomers in a Unique 3 to 1 Subunit Ratio

(2009) John den Engelsman et al.   JOURNAL OF MOLECULAR BIOLOGY

Heat shock protein 27 is involved in SUMO-2/3 modification of heat shock factor 1 and thereby modulates the transcription factor activity

(2009) M Brunet Simioni et al.   ONCOGENE

Significance of α-crystallin heteropolymer with a 3:1 αA/αB ratio: chaperone-like activity, structure and hydrophobicity

(2008) P. N. B. S. Srinivas et al.   BIOCHEMICAL JOURNAL

Heterooligomeric complexes formed by human small heat shock proteins HspB1 (Hsp27) and HspB6 (Hsp20)

(2008) Olesya V. Bukach et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Upregulated HSP27 in human breast cancer cells reduces Herceptin susceptibility by increasing Her2 protein stability

(2008) Se Hun Kang et al.   BMC CANCER

P-Cadherin and β-catenin are useful prognostic markers in breast cancer patients; β-catenin interacts with heat shock protein Hsp27

(2008) Mariel A. Fanelli et al.   CELL STRESS & CHAPERONES

HSP27 regulates IL-1 stimulated IKK activation through interacting with TRAF6 and affecting its ubiquitination

(2008) Y WU et al.   CELLULAR SIGNALLING

Protective Role of Hsp27 Protein Against Gamma Radiation–Induced Apoptosis and Radiosensitization Effects of Hsp27 Gene Silencing in Different Human Tumor Cells

(2008) Marie-Thérèse Aloy et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

αB-Crystallin is a Cytoplasmic Interaction Partner of the Kidney-Specific Cadherin-16

(2008) Cornelia Thedieck et al.   JOURNAL OF MOLECULAR BIOLOGY

Chaperone Hsp27, a Novel Subunit of AUF1 Protein Complexes, Functions in AU-Rich Element-Mediated mRNA Decay

(2008) K. S. Sinsimer et al.   MOLECULAR AND CELLULAR BIOLOGY

Interactive sequences in the molecular chaperone, human αB crystallin modulate the fibrillation of amyloidogenic proteins

(2007) Joy G. Ghosh et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Small heat shock proteins Hsp27 or αB-crystallin and the protein components of neurofibrillary tangles: Tau and neurofilaments

(2007) Cecilia Björkdahl et al.   JOURNAL OF NEUROSCIENCE RESEARCH