Conserved charged residues at the surface and interface of epithelial sodium channel subunits - roles in cell surface expression and the sodium self-inhibition response

The Lhs1/GRP170 Chaperones Facilitate the Endoplasmic Reticulum-associated Degradation of the Epithelial Sodium Channel

(2013) Teresa M. Buck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polarized sorting and trafficking in epithelial cells

(2012) Xinwang Cao et al.   CELL RESEARCH

Epithelial Na+ channel regulation by cytoplasmic and extracellular factors

(2012) Ossama B. Kashlan et al.   EXPERIMENTAL CELL RESEARCH

Role of the Wrist Domain in the Response of the Epithelial Sodium Channel to External Stimuli

(2012) Shujie Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural plasticity and dynamic selectivity of acid-sensing ion channel–spider toxin complexes

(2012) Isabelle Baconguis et al.   NATURE

Role of membrane traffic in the generation of epithelial cell asymmetry

(2012) Gerard Apodaca et al.   NATURE CELL BIOLOGY

Insight into DEG/ENaC Channel Gating from Genetics and Structure

(2012) Amy L. Eastwood et al.   PHYSIOLOGY

Regulation and dysregulation of epithelial Na+ channels

(2011) Lawrence G. Palmer et al.   Clinical and Experimental Nephrology

Epithelial sodium channels (ENaC) are uniformly distributed on motile cilia in the oviduct and the respiratory airways

(2011) Yehoshua Enuka et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Proton-Binding Sites of Acid-Sensing Ion Channel 1

(2011) Hiroshi Ishikita   PLoS One

Transient protein-protein interactions

(2011) S. E. Acuner Ozbabacan et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Charged residues at protein interaction interfaces: Unexpected conservation and orchestrated divergence

(2011) Nan Zhao et al.   PROTEIN SCIENCE

Outlines of the pore in open and closed conformations describe the gating mechanism of ASIC1

(2011) Tianbo Li et al.   Nature Communications

Tissue Renin-Angiotensin-Aldosterone Systems: Targets for Pharmacological Therapy

(2010) Michael Bader   Annual Review of Pharmacology and Toxicology

Conserved residue clusters at protein-protein interfaces and their use in binding site identification

(2010) Mainak Guharoy et al.   BMC BIOINFORMATICS

Identification of Epithelial Na+Channel (ENaC) Intersubunit Cl−Inhibitory Residues Suggests a Trimeric αγβ Channel Architecture

(2010) Daniel M. Collier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A mutation of the epithelial sodium channel associated with atypical cystic fibrosis increases channel open probability and reduces Na+self inhibition

(2010) Robert Rauh et al.   JOURNAL OF PHYSIOLOGY-LONDON

Truncated beta epithelial sodium channel (ENaC) subunits responsible for multi-system pseudohypoaldosteronism support partial activity of ENaC

(2010) Oded Edelheit et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The Endoplasmic Reticulum–associated Degradation of the Epithelial Sodium Channel Requires a Unique Complement of Molecular Chaperones

(2010) Teresa M. Buck et al.   MOLECULAR BIOLOGY OF THE CELL

Sorting things out through endoplasmic reticulum quality control

(2010) Taku Tamura et al.   MOLECULAR MEMBRANE BIOLOGY

Simple and efficient site-directed mutagenesis using two single-primer reactions in parallel to generate mutants for protein structure-function studies

(2009) Oded Edelheit et al.   BMC BIOTECHNOLOGY

Novel Determinants of Epithelial Sodium Channel Gating within Extracellular Thumb Domains

(2009) Ahmad B. Maarouf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ENaC at the Cutting Edge: Regulation of Epithelial Sodium Channels by Proteases

(2009) Thomas R. Kleyman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

(2009) Eric B. Gonzales et al.   NATURE

PoreWalker: A Novel Tool for the Identification and Characterization of Channels in Transmembrane Proteins from Their Three-Dimensional Structure

(2009) Marialuisa Pellegrini-Calace et al.   PLoS Computational Biology

Renin–aldosterone response, urinary Na/K ratio and growth in pseudohypoaldosteronism patients with mutations in epithelial sodium channel (ENaC) subunit genes

(2008) Aaron Hanukoglu et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY