Structural plasticity and dynamic selectivity of acid-sensing ion channel–spider toxin complexes

Molecular mechanism of ATP binding and ion channel activation in P2X receptors

(2012) Motoyuki Hattori et al.   NATURE

Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1

(2012) Roger J.P. Dawson et al.   Nature Communications

Nonproton Ligand Sensing Domain Is Required for Paradoxical Stimulation of Acid-sensing Ion Channel 3 (ASIC3) Channels by Amiloride

(2011) Wei-Guang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Interaction between Two Extracellular Linker Regions Controls Sustained Opening of Acid-sensing Ion Channel 1

(2011) Andreas Springauf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Asp433in the closing gate of ASIC1 determines stability of the open state without changing properties of the selectivity filter or Ca2+block

(2011) Tianbo Li et al.   JOURNAL OF GENERAL PHYSIOLOGY

A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain

(2011) Christopher J. Bohlen et al.   NATURE

Outlines of the pore in open and closed conformations describe the gating mechanism of ASIC1

(2011) Tianbo Li et al.   Nature Communications

Two residues in the extracellular domain convert a nonfunctional ASIC1 into a proton-activated channel

(2010) Tianbo Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The epithelial sodium channel and the control of sodium balance

(2010) Laurent Schild   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Asn415in the β11-β12 Linker Decreases Proton-dependent Desensitization of ASIC1

(2010) Tianbo Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leu85in the β1-β2 Linker of ASIC1 Slows Activation and Decreases the Apparent Proton Affinity by Stabilizing a Closed Conformation

(2010) Tianbo Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Nonproton Ligand Sensor in the Acid-Sensing Ion Channel

(2010) Ye Yu et al.   NEURON

Acid-Sensing Ion Channels (ASICs): Pharmacology and implication in pain

(2010) Emmanuel Deval et al.   PHARMACOLOGY & THERAPEUTICS

Native and recombinant ASIC1a receptors conduct negligible Ca2+ entry

(2009) Damien S.K. Samways et al.   CELL CALCIUM

Identification of Protein Domains That Control Proton and Calcium Sensitivity of ASIC1a

(2009) Thomas Sherwood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Docking and MD Simulations of the Interaction of the Tarantula Peptide Psalmotoxin-1 with ASIC1a Channels Using a Homology Model

(2009) Francesco Pietra   Journal of Chemical Information and Modeling

Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

(2009) Eric B. Gonzales et al.   NATURE

Restoring Acid-Sensing Ion Channel-1a in the Amygdala of Knock-Out Mice Rescues Fear Memory But Not Unconditioned Fear Responses

(2008) M. W. Coryell et al.   JOURNAL OF NEUROSCIENCE

BacMam system for high-level expression of recombinant soluble and membrane glycoproteins for structural studies

(2008) Abhiram Dukkipati et al.   PROTEIN EXPRESSION AND PURIFICATION