Telomere shortening in human diseases

Accelerated in vivo epidermal telomere loss in Werner syndrome

(2016) Naoshi Ishikawa et al.   Aging-US

Association of Shorter Leukocyte Telomere Repeat Length With Dementia and Mortality

(2012) Lawrence S. Honig et al.   ARCHIVES OF NEUROLOGY

Werner syndrome protein suppresses the formation of large deletions during the replication of human telomeric sequences

(2012) Rama Rao Damerla et al.   CELL CYCLE

Structure of Mre11–Nbs1 complex yields insights into ataxia-telangiectasia–like disease mutations and DNA damage signaling

(2012) Christian B Schiller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The roles of WRN and BLM RecQ helicases in the Alternative Lengthening of Telomeres

(2012) Aaron Mendez-Bermudez et al.   NUCLEIC ACIDS RESEARCH

The Relationship between Telomere Length and Mortality in Chronic Obstructive Pulmonary Disease (COPD)

(2012) Jee Lee et al.   PLoS One

Short Telomere Length, Myocardial Infarction, Ischemic Heart Disease, and Early Death

(2011) Maren Weischer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Telomere length is age-dependent and reduced in monocytes of Alzheimer patients

(2011) Tanja Hochstrasser et al.   EXPERIMENTAL GERONTOLOGY

Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita

(2011) F. Zhong et al.   GENES & DEVELOPMENT

Short Leukocyte Telomere Length Is Associated with Aortic Dissection

(2011) Jiangtao Yan et al.   INTERNAL MEDICINE

Leukocyte Telomere Length and Mortality in the Cardiovascular Health Study

(2011) A. L. Fitzpatrick et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Short telomeres result in chromosomal instability in hematopoietic cells and precede malignant evolution in human aplastic anemia

(2011) R T Calado et al.   LEUKEMIA

Telomere shortening occurs early during gastrocarcinogenesis

(2011) Yunchuan Mu et al.   MEDICAL ONCOLOGY

Telomerase and idiopathic pulmonary fibrosis

(2011) Mary Armanios   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Mre11 modulates the fidelity of fusion between short telomeres in human cells

(2011) Maira Tankimanova et al.   NUCLEIC ACIDS RESEARCH

Association of shorter mean telomere length with large artery stiffness in patients with coronary heart disease

(2010) Yun-Ying Wang et al.   Aging Male

Differential regulation of MRN (Mre11–Rad50–Nbs1) complex subunits and telomerase activity in cancer cells

(2010) C.V. Kavitha et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human Topoisomerase IIIα Is a Single-stranded DNA Decatenase That Is Stimulated by BLM and RMI1

(2010) Jay Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytomegalovirus Infection Reduces Telomere Length of the Circulating T Cell Pool

(2010) P. J. E. J. van de Berg et al.   JOURNAL OF IMMUNOLOGY

Study of telomere length and different markers of oxidative stress in patients with Parkinson’s disease

(2010) G. Watfa et al.   Journal of Nutrition Health & Aging

Telomeric protein TRF2 protects Holliday junctions with telomeric arms from displacement by the Werner syndrome helicase

(2010) Gerald J. Nora et al.   NUCLEIC ACIDS RESEARCH

Hyper telomere recombination accelerates replicative senescence and may promote premature aging

(2010) R. T. Hagelstrom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shortened Telomeres in Circulating Leukocytes of Patients with Chronic Obstructive Pulmonary Disease

(2009) Laurent Savale et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Telomere Extension Occurs at Most Chromosome Ends and Is Uncoupled from Fill-In in Human Cancer Cells

(2009) Yong Zhao et al.   CELL

FANCC suppresses short telomere-initiated telomere sister chromatid exchange

(2009) David B. Rhee et al.   HUMAN MOLECULAR GENETICS

Telomeric D-loops Containing 8-Oxo-2′-deoxyguanosine Are Preferred Substrates for Werner and Bloom Syndrome Helicases and Are Bound by POT1

(2009) Avik Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mre11 Complex and the Response to Dysfunctional Telomeres

(2009) C. L. Attwooll et al.   MOLECULAR AND CELLULAR BIOLOGY

Multiple roles for MRE11 at uncapped telomeres

(2009) Yibin Deng et al.   NATURE

A role for monoubiquitinated FANCD2 at telomeres in ALT cells

(2009) Qiang Fan et al.   NUCLEIC ACIDS RESEARCH

TINF2, a Component of the Shelterin Telomere Protection Complex, Is Mutated in Dyskeratosis Congenita

(2008) Sharon A. Savage et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Telomere Shortening in Familial and Sporadic Pulmonary Fibrosis

(2008) Jennifer T. Cronkhite et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

TINF2 mutations result in very short telomeres: analysis of a large cohort of patients with dyskeratosis congenita and related bone marrow failure syndromes

(2008) A. J. Walne et al.   BLOOD

Telomere length in Hepatitis C

(2008) Y. Kitay-Cohen et al.   CANCER GENETICS AND CYTOGENETICS

DNA damage response at functional and dysfunctional telomeres

(2008) M. P. Longhese   GENES & DEVELOPMENT

BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome

(2008) T. R. Singh et al.   GENES & DEVELOPMENT

RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability

(2008) D. Xu et al.   GENES & DEVELOPMENT

Mechanism and substrate specificity of telomeric protein POT1 stimulation of the Werner syndrome helicase

(2008) Gregory Sowd et al.   NUCLEIC ACIDS RESEARCH

Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita

(2008) T. Vulliamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Telomerase redefined: Integrated regulation of hTR and hTERT for telomere maintenance and telomerase activity

(2007) C.J. Cairney et al.   BIOCHIMIE