The 5′-untranslated region regulates ATF5 mRNA stability via nonsense-mediated mRNA decay in response to environmental stress

The Endoplasmic Reticulum Stress Transducer BBF2H7 Suppresses Apoptosis by Activating the ATF5-MCL1 Pathway in Growth Plate Cartilage

(2012) Soutarou Izumi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleophosmin (NPM1/B23) Interacts with Activating Transcription Factor 5 (ATF5) Protein and Promotes Proteasome- and Caspase-dependent ATF5 Degradation in Hepatocellular Carcinoma Cells

(2012) Xijun Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BCL-2 Is a Downstream Target of ATF5 That Mediates the Prosurvival Function of ATF5 in a Cell Type-dependent Manner

(2011) Douglas Dluzen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HSP70 Protein Promotes Survival of C6 and U87 Glioma Cells by Inhibition of ATF5 Degradation

(2011) Guangfu Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p300-Dependent ATF5 Acetylation Is Essential for Egr-1 Gene Activation and Cell Proliferation and Survival

(2011) D. X. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulated ATF5 loss-of-function in adult mice blocks formation and causes regression/eradication of gliomas

(2011) A Arias et al.   ONCOGENE

Upf1 Senses 3′UTR Length to Potentiate mRNA Decay

(2010) J. Robert Hogg et al.   CELL

Stress-sensitive Regulation of IFRD1 mRNA Decay Is Mediated by an Upstream Open Reading Frame

(2010) Chenyang Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications

(2010) Zhi Sheng et al.   NATURE MEDICINE

Cadmium interferes with the degradation of ATF5 via a post-ubiquitination step of the proteasome degradation pathway

(2009) Hiroyuki Uekusa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors

(2009) Pamela Nicholson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nonsense-mediated mRNA decay (NMD) mechanisms

(2009) Saverio Brogna et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Re-Expression of Transcription Factor ATF5 in Hepatocellular Carcinoma Induces G2-M Arrest

(2008) J. W-M. Gho et al.   CANCER RESEARCH

SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs

(2008) C. Gong et al.   GENES & DEVELOPMENT

Cdc34-mediated Degradation of ATF5 Is Blocked by Cisplatin

(2008) Yuanyan Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of eIF2 DirectsATF5Translational Control in Response to Diverse Stress Conditions

(2008) Donghui Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxic Inhibition of Nonsense-Mediated RNA Decay Regulates Gene Expression and the Integrated Stress Response

(2008) L. B. Gardner   MOLECULAR AND CELLULAR BIOLOGY