Mechanical activation of mammalian target of rapamycin pathway is required for cartilage development

Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling

(2013) Wentian Yang et al.   NATURE

MiR-365: a mechanosensitive microRNA stimulates chondrocyte differentiation through targeting histone deacetylase 4

(2011) Ying-Jie Guan et al.   FASEB JOURNAL

The skeleton: a multi-functional complex organ. The growth plate chondrocyte and endochondral ossification

(2011) E J Mackie et al.   JOURNAL OF ENDOCRINOLOGY

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

(2010) Shomit Sengupta et al.   MOLECULAR CELL

Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy

(2010) C A Sparks et al.   ONCOGENE

TOR signaling in invertebrates

(2009) Alexandre Soulard et al.   CURRENT OPINION IN CELL BIOLOGY

Oscillatory Flow-induced Proliferation of Osteoblast-like Cells Is Mediated by αvβ3and β1Integrins through Synergistic Interactions of Focal Adhesion Kinase and Shc with Phosphatidylinositol 3-Kinase and the Akt/mTOR/p70S6K Pathway

(2009) Ding-Yu Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Growth plate mechanics and mechanobiology. A survey of present understanding

(2009) Isabelle Villemure et al.   JOURNAL OF BIOMECHANICS

The effect of rapamycin on bone growth in rabbits

(2009) Chanika Phornphutkul et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Why high frequency of distraction improved the bone formation in distraction osteogenesis?

(2009) Baohui Ji et al.   MEDICAL HYPOTHESES

Is Bone's Response to Mechanical Signals Dominated by Muscle Forces?

(2009) ALEXANDER G. ROBLING   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Signalling cascades in mechanotransduction: cell-matrix interactions and mechanical loading

(2009) L. Ramage et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

The Effect of Mechanical Loading on the Metabolism of Growth Plate Chondrocytes

(2008) Masashi Ueki et al.   ANNALS OF BIOMEDICAL ENGINEERING

Rapamycin affects early fracture healing in mice

(2008) J H Holstein et al.   BRITISH JOURNAL OF PHARMACOLOGY

mTOR signaling contributes to chondrocyte differentiation

(2008) Chanika Phornphutkul et al.   DEVELOPMENTAL DYNAMICS

Identification of Mechanosensitive Genes during Embryonic Bone Formation

(2008) Niamh C. Nowlan et al.   PLoS Computational Biology

The molecular functions of Shp2 in the Ras/Mitogen-activated protein kinase (ERK1/2) pathway

(2007) Marie Dance et al.   CELLULAR SIGNALLING