The skeleton: a multi-functional complex organ. The growth plate chondrocyte and endochondral ossification

Intraspecies disparity in growth rate is associated with differences in expression of local growth plate regulators

(2010) M. A. Tryfonidou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Heparan Sulfate-Dependent Signaling of Fibroblast Growth Factor 18 by Chondrocyte-Derived Perlecan

(2010) Christine Y. Chuang et al.   BIOCHEMISTRY

Zfp521 Is a Target Gene and Key Effector of Parathyroid Hormone-Related Peptide Signaling in Growth Plate Chondrocytes

(2010) Diego Correa et al.   DEVELOPMENTAL CELL

Neogenin Regulation of BMP-Induced Canonical Smad Signaling and Endochondral Bone Formation

(2010) Zheng Zhou et al.   DEVELOPMENTAL CELL

The skeletal dysplasias

(2010) Deborah Krakow et al.   GENETICS IN MEDICINE

Periostin expression distinguishes between light and dark hypertrophic chondrocytes

(2010) Kuan-Sheng Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The matrilins: Modulators of extracellular matrix assembly

(2010) Andreas R. Klatt et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Loss of skeletal mineralization by the simultaneous ablation of PHOSPHO1 and alkaline phosphatase function: A unified model of the mechanisms of initiation of skeletal calcification

(2010) Manisha C Yadav et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Thyroid hormone-mediated growth and differentiation of growth plate chondrocytes involves IGF-1 modulation of β-catenin signaling

(2010) Lai Wang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3

(2010) D. C. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Septoclast Deficiency Accompanies Postnatal Growth Plate Chondrodysplasia in the Toothless (tl) Osteopetrotic, Colony-Stimulating Factor-1 (CSF-1)-Deficient Rat and Is Partially Responsive to CSF-1 Injections

(2009) Alison Gartland et al.   AMERICAN JOURNAL OF PATHOLOGY

Proteinases involved in matrix turnover during cartilage and bone breakdown

(2009) Tim E. Cawston et al.   CELL AND TISSUE RESEARCH

Inflammatory cytokines and the GH/IGF-I axis: novel actions on bone growth

(2009) C. Pass et al.   CELL BIOCHEMISTRY AND FUNCTION

Cartilage and Bone Extracellular Matrix

(2009) Chiara Gentili/snm et al.   CURRENT PHARMACEUTICAL DESIGN

Sulfation of chondroitin sulfate proteoglycans is necessary for proper Indian hedgehog signaling in the developing growth plate

(2009) M. Cortes et al.   DEVELOPMENT

BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation

(2009) K. N. Retting et al.   DEVELOPMENT

Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb

(2009) K. Matsumoto et al.   DEVELOPMENT

The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization

(2009) K. S. Joeng et al.   DEVELOPMENT

Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3

(2009) Manuela Wuelling et al.   DEVELOPMENTAL BIOLOGY

Sox9 directly promotes Bapx1 gene expression to repress Runx2 in chondrocytes

(2009) Satoshi Yamashita et al.   EXPERIMENTAL CELL RESEARCH

A novel domain in histone deacetylase 1 and 2 mediates repression of cartilage-specific genes in human chondrocytes

(2009) Sohee Hong et al.   FASEB JOURNAL

Fell-Muir Lecture: Proteoglycans and more - from molecules to biology

(2009) Dick Heinegård   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Deficiency of annexins A5 and A6 induces complex changes in the transcriptome of growth plate cartilage but does not inhibit the induction of mineralization

(2009) Daniele Belluoccio et al.   JOURNAL OF BONE AND MINERAL RESEARCH

PTHrP prevents chondrocyte premature hypertrophy by inducing cyclin-D1-dependent Runx2 and Runx3 phosphorylation, ubiquitylation and proteasomal degradation

(2009) M. Zhang et al.   JOURNAL OF CELL SCIENCE

Transcriptional networks controlling chondrocyte proliferation and differentiation during endochondral ossification

(2009) Manuela Wuelling et al.   PEDIATRIC NEPHROLOGY

Epiphyseal Fusion in the Human Growth Plate Does not Involve Classical Apoptosis

(2009) Joyce Emons et al.   PEDIATRIC RESEARCH

New Insight on FGFR3-Related Chondrodysplasias Molecular Physiopathology Revealed by Human Chondrocyte Gene Expression Profiling

(2009) Laurent Schibler et al.   PLoS One

Skeletal Abnormalities in Mice Lacking Extracellular Matrix Proteins, Thrombospondin-1, Thrombospondin-3, Thrombospondin-5, and Type IX Collagen

(2008) Karen L. Posey et al.   AMERICAN JOURNAL OF PATHOLOGY

Evidence of a novel aggrecan-degrading activity in cartilage: Studies of mice deficient in both ADAMTS-4 and ADAMTS-5

(2008) Fraser M. Rogerson et al.   ARTHRITIS AND RHEUMATISM

Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy

(2008) K. K. Mak et al.   DEVELOPMENT

Heparan sulfate proteoglycans: A GAGgle of skeletal-hematopoietic regulators

(2008) Kathryn D. Rodgers et al.   DEVELOPMENTAL DYNAMICS

Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification

(2008) C. Settembre et al.   GENES & DEVELOPMENT

Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome

(2008) Dobrawa Napierala et al.   HUMAN MOLECULAR GENETICS

FGFR3 promotes synchondrosis closure and fusion of ossification centers through the MAPK pathway

(2008) T. Matsushita et al.   HUMAN MOLECULAR GENETICS

Inhibition of  -catenin signaling causes defects in postnatal cartilage development

(2008) M. Chen et al.   JOURNAL OF CELL SCIENCE

Cellular methods in cartilage research: Primary human chondrocytes in culture and chondrogenesis in human bone marrow stem cells

(2008) Simon R. Tew et al.   METHODS

Ablation of collagen IX and COMP disrupts epiphyseal cartilage architecture

(2007) K BLUMBACH et al.   MATRIX BIOLOGY