Molecular determinants of desensitization in an ENaC/degenerin channel

Gating Transitions in the Palm Domain of ASIC1a

(2013) Margaret C. Della Vecchia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acid-sensing ion channels in pain and disease

(2013) John A. Wemmie et al.   NATURE REVIEWS NEUROSCIENCE

Structural plasticity and dynamic selectivity of acid-sensing ion channel–spider toxin complexes

(2012) Isabelle Baconguis et al.   NATURE

Insight into DEG/ENaC Channel Gating from Genetics and Structure

(2012) Amy L. Eastwood et al.   PHYSIOLOGY

Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1

(2012) Roger J.P. Dawson et al.   Nature Communications

The Interaction between Two Extracellular Linker Regions Controls Sustained Opening of Acid-sensing Ion Channel 1

(2011) Andreas Springauf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Outlines of the pore in open and closed conformations describe the gating mechanism of ASIC1

(2011) Tianbo Li et al.   Nature Communications

The epithelial sodium channel and the control of sodium balance

(2010) Laurent Schild   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A Combined Computational and Functional Approach Identifies New Residues Involved in pH-dependent Gating of ASIC1a

(2010) Luz Angélica Liechti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Contact Region between Three Domains of the Extracellular Loop of ASIC1a Is Critical for Channel Function

(2010) Benoîte Bargeton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Constraint-based, Homology Model of the Extracellular Domain of the Epithelial Na+Channel α Subunit Reveals a Mechanism of Channel Activation by Proteases

(2010) Ossama B. Kashlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Asn415in the β11-β12 Linker Decreases Proton-dependent Desensitization of ASIC1

(2010) Tianbo Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leu85in the β1-β2 Linker of ASIC1 Slows Activation and Decreases the Apparent Proton Affinity by Stabilizing a Closed Conformation

(2010) Tianbo Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

(2009) Eric B. Gonzales et al.   NATURE

Interaction of the Aromatics Tyr-72/Trp-288 in the Interface of the Extracellular and Transmembrane Domains Is Essential for Proton Gating of Acid-sensing Ion Channels

(2008) Tianbo Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY