Specific needs of dopamine neurons for stimulation in order to survive: implication for Parkinson disease

Bee Venom and Its Component Apamin as Neuroprotective Agents in a Parkinson Disease Mouse Model

(2013) Daniel Alvarez-Fischer et al.   PLoS One

Use of Calcium Channel Blockers and Parkinson’s Disease

(2012) Björn Pasternak et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

TRPC Channels and their Implications for Neurological Diseases

(2012) Senthil Selvaraj et al.   CNS & Neurological Disorders-Drug Targets

α-Synuclein Controls Mitochondrial Calcium Homeostasis by Enhancing Endoplasmic Reticulum-Mitochondria Interactions

(2012) Tito Calì et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling

(2012) Senthil Selvaraj et al.   JOURNAL OF CLINICAL INVESTIGATION

Activity-dependent regulation of the dopamine phenotype in substantia nigra neurons

(2012) Tim Aumann et al.   JOURNAL OF NEUROCHEMISTRY

The α7 nicotinic acetylcholine receptor ligands methyllycaconitine, NS6740 and GTS-21 reduce lipopolysaccharide-induced TNF-α release from microglia

(2012) Morten S. Thomsen et al.   JOURNAL OF NEUROIMMUNOLOGY

α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation

(2012) Yuan Liu et al.   Journal of Neuroinflammation

3-[(2,4-dimethoxy)benzylidene]-anabaseine dihydrochloride protects against 6-hydroxydopamine-induced parkinsonian neurodegeneration through α7 nicotinic acetylcholine receptor stimulation in rats

(2012) Syuuichirou Suzuki et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Nicotine as a potential neuroprotective agent for Parkinson's disease

(2012) Maryka Quik et al.   MOVEMENT DISORDERS

Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic

(2012) Aaron A. Thompson et al.   NATURE

Effectiveness of acupuncture and bee venom acupuncture in idiopathic Parkinson's disease

(2012) Seung-Yeon Cho et al.   PARKINSONISM & RELATED DISORDERS

Functional Upregulation of Ca2+ -Activated K+ Channels in the Development of Substantia Nigra Dopamine Neurons

(2012) José A. Ramírez-Latorre   PLoS One

Dihydropyridine calcium channel blockers and the progression of parkinsonism

(2011) Connie Marras et al.   ANNALS OF NEUROLOGY

Analgesic conotoxins: block and G protein-coupled receptor modulation of N-type (CaV2.2) calcium channels

(2011) David J Adams et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neuroprotection of midbrain dopamine neurons by nicotine is gated by cytoplasmic Ca2+

(2011) Damien Toulorge et al.   FASEB JOURNAL

Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's disease

(2011) Cameron H. Good et al.   FASEB JOURNAL

Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models

(2011) Andrii Domanskyi et al.   FASEB JOURNAL

Etiology and pathogenesis of Parkinson's disease

(2011) Anthony H. Schapira et al.   MOVEMENT DISORDERS

Age and α-synuclein expression interact to reveal a dependence of dopaminergic axons on endogenous Akt/PKB signaling

(2011) Sang Ryong Kim et al.   NEUROBIOLOGY OF DISEASE

Neuroprotective effects of neurokinin receptor one in dopaminergic neurons are mediated through Akt/PKB cell signaling pathway

(2011) John M.T. Chu et al.   NEUROPHARMACOLOGY

Dopamine release in the basal ganglia

(2011) M.E. Rice et al.   NEUROSCIENCE

Tachykinins and the hypothalamo–pituitary–gonadal axis: An update

(2011) Mercedes Lasaga et al.   PEPTIDES

What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease

(2011) Olga Corti et al.   PHYSIOLOGICAL REVIEWS

Role of Kv1 Potassium Channels in Regulating Dopamine Release and Presynaptic D2 Receptor Function

(2011) Philippe Martel et al.   PLoS One

Prolonged Membrane Depolarization Enhances Midbrain Dopamine Neuron Differentiation via Epigenetic Histone Modifications

(2011) Xi-Biao He et al.   STEM CELLS

Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population

(2010) M. Saad et al.   HUMAN MOLECULAR GENETICS

Cholinergic mesencephalic neurons are involved in gait and postural disorders in Parkinson disease

(2010) Carine Karachi et al.   JOURNAL OF CLINICAL INVESTIGATION

Neuropathology of sporadic Parkinson disease before the appearance of parkinsonism: preclinical Parkinson disease

(2010) Isidre Ferrer et al.   JOURNAL OF NEURAL TRANSMISSION

KATP channel blockade protects midbrain dopamine neurons by repressing a glia-to-neuron signaling cascade that ultimately disrupts mitochondrial calcium homeostasis

(2010) Damien Toulorge et al.   JOURNAL OF NEUROCHEMISTRY

Pharmacological Modulation of the Gating Properties of Small Conductance Ca2+-Activated K+ Channels Alters the Firing Pattern of Dopamine Neurons In Vivo

(2010) Kjartan F. Herrik et al.   JOURNAL OF NEUROPHYSIOLOGY

Enhanced Striatal Dopamine Transmission and Motor Performance with LRRK2 Overexpression in Mice Is Eliminated by Familial Parkinson's Disease Mutation G2019S

(2010) X. Li et al.   JOURNAL OF NEUROSCIENCE

Brain Interstitial Nociceptin/Orphanin FQ Levels are Elevated in Parkinson's Disease

(2010) Matteo Marti et al.   MOVEMENT DISORDERS

Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease

(2010) Christian Lüscher et al.   NATURE REVIEWS NEUROSCIENCE

T-type calcium channel antagonism produces antipsychotic-like effects and reduces stimulant-induced glutamate release in the nucleus accumbens of rats

(2010) Jason M. Uslaner et al.   NEUROPHARMACOLOGY

Neuroprotection by caffeine: time course and role of its metabolites in the MPTP model of Parkinson's disease

(2010) K. Xu et al.   NEUROSCIENCE

Nicotinic acetylcholine receptors and the ascending dopamine pathways

(2009) Phil D. Livingstone et al.   BIOCHEMICAL PHARMACOLOGY

Heterodimerization of ORL1 and Opioid Receptors and Its Consequences for N-type Calcium Channel Regulation

(2009) Rhian M. Evans et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protection of midbrain dopaminergic neurons by the end-product of purine metabolism uric acid: potentiation by low-level depolarization

(2009) Serge Guerreiro et al.   JOURNAL OF NEUROCHEMISTRY

Mobilization of Calcium from Intracellular Stores Facilitates Somatodendritic Dopamine Release

(2009) J. C. Patel et al.   JOURNAL OF NEUROSCIENCE

cAMP-Mediated Stimulation of Tyrosine Hydroxylase mRNA Translation Is Mediated by Polypyrimidine-Rich Sequences within Its 3'-Untranslated Region and Poly(C)-Binding Protein 2

(2009) L. Xu et al.   MOLECULAR PHARMACOLOGY

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

(2009) Wataru Satake et al.   NATURE GENETICS

Neuroprotective effects of bee venom pharmaceutical acupuncture in acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease

(2009) Ah-Reum Doo et al.   NEUROLOGICAL RESEARCH

Personality, Addiction, Dopamine: Insights from Parkinson's Disease

(2009) Alain Dagher et al.   NEURON

Modulation of firing activity by ATP in dopamine neurons of the rat substantia nigra pars compacta

(2009) Y.M. Choi et al.   NEUROSCIENCE

Paraxanthine, the Primary Metabolite of Caffeine, Provides Protection against Dopaminergic Cell Death via Stimulation of Ryanodine Receptor Channels

(2008) S. Guerreiro et al.   MOLECULAR PHARMACOLOGY

Atypical parkinsonism in the Caribbean island of Guadeloupe: Etiological role of the mitochondrial complex I inhibitor annonacin

(2008) Annie Lannuzel et al.   MOVEMENT DISORDERS

Modeling PD pathogenesis in mice: Advantages of a chronic MPTP protocol

(2008) Gloria E. Meredith et al.   PARKINSONISM & RELATED DISORDERS

Adenosine Prevents the Death of Mesencephalic Dopaminergic Neurons by a Mechanism that Involves Astrocytes

(2003) Patrick P. Michel et al.   JOURNAL OF NEUROCHEMISTRY