α-Synuclein Interacts with Glucocerebrosidase Providing a Molecular Link between Parkinson and Gaucher Diseases

Residue-Specific Fluorescent Probes of α-Synuclein: Detection of Early Events at the N- and C-Termini during Fibril Assembly

(2011) Thai Leong Yap et al.   BIOCHEMISTRY

Glucocerebrosidase is present in α-synuclein inclusions in Lewy body disorders

(2010) Ozlem Goker-Alpan et al.   ACTA NEUROPATHOLOGICA

Early Aggregation Steps in α-Synuclein as Measured by FCS and FRET: Evidence for a Contagious Conformational Change

(2010) Sangeeta Nath et al.   BIOPHYSICAL JOURNAL

The Role of Glucocerebrosidase Mutations in Parkinson Disease and Lewy Body Disorders

(2010) Arash Velayati et al.   Current Neurology and Neuroscience Reports

Lysosomal Degradation of α-Synucleinin Vivo

(2010) Sally K. Mak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Lipid-binding Domain of Wild Type and Mutant α-Synuclein

(2010) Elka R. Georgieva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

X-ray and Biochemical Analysis of N370S Mutant Human Acid β-Glucosidase

(2010) Ronnie R. Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tryptophan Probes at the α-Synuclein and Membrane Interface

(2010) Candace M. Pfefferkorn et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Gaucher disease and parkinsonism, a molecular link theory

(2010) Ehud Goldin   MOLECULAR GENETICS AND METABOLISM

NMR determination of pKa values in α-synuclein

(2010) Robyn L. Croke et al.   PROTEIN SCIENCE

 -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

(2010) J. Burre et al.   SCIENCE

Biophysics of Parkinsons Disease: Structure and Aggregation of α- Synuclein

(2009) Vladimir Uversky et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Multiple Tight Phospholipid-Binding Modes of α-Synuclein Revealed by Solution NMR Spectroscopy

(2009) Christina R. Bodner et al.   JOURNAL OF MOLECULAR BIOLOGY

On the mechanism of internalization of α-synuclein into microglia: roles of ganglioside GM1 and lipid raft

(2009) Ji-Young Park et al.   JOURNAL OF NEUROCHEMISTRY

α-Synuclein and neuronal cell death

(2009) Mark R Cookson   Molecular Neurodegeneration

Alpha-synuclein-glucocerebrosidase interactions in pharmacological Gaucher models: A biological link between Gaucher disease and parkinsonism

(2009) Amy B. Manning-Boğ et al.   NEUROTOXICOLOGY

Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

(2009) E. Sidransky et al.   NEW ENGLAND JOURNAL OF MEDICINE

Do amyloid oligomers act as traps for misfolded proteins? A hypothesis

(2008) James M. Gruschus   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Cathepsin D: A cellular roadmap

(2008) Nousheen Zaidi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Phosphorylation, lipid raft interaction and traffic of α-synuclein in a yeast model for Parkinson

(2008) Piotr Zabrocki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Acid β-glucosidase: insights from structural analysis and relevance to Gaucher disease therapy

(2008) Yaacov Kacher et al.   BIOLOGICAL CHEMISTRY

Concentration Dependence of α-Synuclein Fibril Length Assessed by Quantitative Atomic Force Microscopy and Statistical-Mechanical Theory

(2008) Martijn E. van Raaij et al.   BIOPHYSICAL JOURNAL

The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease

(2008) T. Pan et al.   BRAIN

Emerging pathways in genetic Parkinson's disease: Potential role of ceramide metabolism in Lewy body disease

(2008) Jose Bras et al.   FEBS Journal

Gaucher disease: mutation and polymorphism spectrum in the glucocerebrosidase gene (GBA)

(2008) Kathleen S. Hruska et al.   HUMAN MUTATION

Multiparametric Fluorescence Detection of Early Stages in the Amyloid Protein Aggregation of Pyrene-labeled α-Synuclein

(2008) Shyamala Thirunavukkuarasu et al.   JOURNAL OF MOLECULAR BIOLOGY

Copper(II) Binding to α-Synuclein, the Parkinson’s Protein

(2008) Jennifer C. Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of membrane-bound  -synuclein from site-directed spin labeling and computational refinement

(2008) C. C. Jao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Very fast prediction and rationalization of pKa values for protein-ligand complexes

(2008) Delphine C. Bas et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS