Novel orally active epoxyeicosatrienoic acid (EET) analogs attenuate cisplatin nephrotoxicity

Delivery of AAV2-CYP2J2 Protects Remnant Kidney in the 5/6-Nephrectomized Rat via Inhibition of Apoptosis and Fibrosis

(2012) Gang Zhao et al.   HUMAN GENE THERAPY

Epoxyeicosatrienoic acids protect rat hearts against tumor necrosis factor-α-induced injury

(2012) Gang Zhao et al.   JOURNAL OF LIPID RESEARCH

Epoxides and Soluble Epoxide Hydrolase in Cardiovascular Physiology

(2012) John D. Imig   PHYSIOLOGICAL REVIEWS

Pharmacological AMP-kinase activators have compartment-specific effects on cell physiology

(2011) Mohamed Kodiha et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

An integrative view of the pathophysiological events leading to cisplatin nephrotoxicity

(2011) Penélope D. Sánchez-González et al.   CRITICAL REVIEWS IN TOXICOLOGY

Indirect comparison of the efficacy of cetuximab and cisplatin in squamous cell carcinoma of the head and neck

(2011) Adrian R. Levy et al.   CURRENT MEDICAL RESEARCH AND OPINION

Abrogation of cisplatin-induced nephrotoxicity in mice by alpha lipoic acid through ameliorating oxidative stress and enhancing gene expression of antioxidant enzymes

(2011) Hesham A. El-Beshbishy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy

(2011) Partha Mukhopadhyay et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cost Effectiveness of Treatment with New Agents in Advanced Non-Small-Cell Lung Cancer

(2011) Mathilda L. Bongers et al.   PHARMACOECONOMICS

Cardioprotective effect of a dual acting epoxyeicosatrienoic acid analogue towards ischaemia reperfusion injury

(2010) SN Batchu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Targeting Epoxides for Organ Damage in Hypertension

(2010) John D Imig   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Amelioration of cisplatin nephrotoxicity by genetic or pharmacologic blockade of prostaglandin synthesis

(2010) Zhanjun Jia et al.   KIDNEY INTERNATIONAL

Nephrotoxicity From Chemotherapeutic Agents: Clinical Manifestations, Pathobiology, and Prevention/Therapy

(2010) Mark A. Perazella et al.   SEMINARS IN NEPHROLOGY

Mechanisms of Cisplatin Nephrotoxicity

(2010) Ronald P. Miller et al.   Toxins

Development of Epoxyeicosatrienoic Acid Analogs with in Vivo Anti-Hypertensive Actions

(2010) John D. Imig et al.   Frontiers in Physiology

Cisplatin compromises myocardial contractile function and mitochondrial ultrastructure: Role of endoplasmic reticulum stress

(2009) Heng Ma et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Soluble Epoxide Hydrolase, a Target with Multiple Opportunities for Cardiovascular Drug Discovery

(2009) Joseph Marino Jr.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) Surrogates Containing Epoxide Bioisosteres: Influence upon Vascular Relaxation and Soluble Epoxide Hydrolase Inhibition

(2009) J. R. Falck et al.   JOURNAL OF MEDICINAL CHEMISTRY

Epoxyeicosatrienoic Acid Agonist Rescues the Metabolic Syndrome Phenotype of HO-2-Null Mice

(2009) K. Sodhi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases

(2009) John D. Imig et al.   NATURE REVIEWS DRUG DISCOVERY

Endoplasmic Reticulum Stress in the Kidney as a Novel Mediator of Kidney Injury

(2009) Reiko Inagi   NEPHRON EXPERIMENTAL NEPHROLOGY

Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart

(2008) Garrett J. Gross et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Attenuation of cisplatin nephrotoxicity by inhibition of soluble epoxide hydrolase

(2008) Alan R. Parrish et al.   CELL BIOLOGY AND TOXICOLOGY

Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto–Kakizaki rats

(2008) Jeffrey J. Olearczyk et al.   CLINICAL SCIENCE

Enhancement of Cisplatin [cis-Diammine Dichloroplatinum (II)] Cytotoxicity by O6-Benzylguanine Involves Endoplasmic Reticulum Stress

(2008) C. A. Rabik et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies

(2008) N. Pabla et al.   KIDNEY INTERNATIONAL