Strain-dependent dysregulation of one-carbon metabolism in male mice is associated with choline- and folate-deficient diet-induced liver injury

Choline intake in a large cohort of patients with nonalcoholic fatty liver disease

(2012) Anthony L Guerrerio et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Reducing endoplasmic reticulum stress does not improve steatohepatitis in mice fed a methionine- and choline-deficient diet

(2012) Anne S. Henkel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Endoplasmic Reticulum Stress in Nonalcoholic Fatty Liver Disease

(2012) Michael J. Pagliassotti   Annual Review of Nutrition

Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism

(2012) Volodymyr Tryndyak et al.   FASEB JOURNAL

Ten Years of the Collaborative Cross

(2012) David W. Threadgill et al.   GENETICS

Interstrain differences in liver injury and one-carbon metabolism in alcohol-fed mice

(2012) Masato Tsuchiya et al.   HEPATOLOGY

Plasma microRNAs are sensitive indicators of inter-strain differences in the severity of liver injury induced in mice by a choline- and folate-deficient diet

(2012) Volodymyr P. Tryndyak et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A Conserved SREBP-1/Phosphatidylcholine Feedback Circuit Regulates Lipogenesis in Metazoans

(2011) Amy K. Walker et al.   CELL

Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression

(2011) Karen D. Corbin et al.   CURRENT OPINION IN GASTROENTEROLOGY

Deletion of Betaine-HomocysteineS-Methyltransferase in Mice Perturbs Choline and 1-Carbon Metabolism, Resulting in Fatty Liver and Hepatocellular Carcinomas

(2011) Ya-Wen Teng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway

(2011) Elena Bravo et al.   Lipids in Health and Disease

Molecular alterations in hepatocarcinogenesis induced by dietary methyl deficiency

(2011) Igor P. Pogribny et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Genetic determinants of susceptibility and severity in nonalcoholic fatty liver disease

(2011) Ann K Daly et al.   Expert Review of Gastroenterology & Hepatology

Update on hepatic stellate cells: pathogenic role in liver fibrosis and novel isolation techniques

(2011) Frank Tacke et al.   Expert Review of Gastroenterology & Hepatology

Compartmentalization of Mammalian Folate-Mediated One-Carbon Metabolism

(2010) Anne S. Tibbetts et al.   Annual Review of Nutrition

New Insights from Rodent Models of Fatty Liver Disease

(2010) Jacquelyn J. Maher   ANTIOXIDANTS & REDOX SIGNALING

Recent advances in nonalcoholic fatty liver disease

(2010) Onpan Cheung et al.   CURRENT OPINION IN GASTROENTEROLOGY

Deletion of murine choline dehydrogenase results in diminished sperm motility

(2010) Amy R. Johnson et al.   FASEB JOURNAL

Stress Signaling in the Methionine-Choline–Deficient Model of Murine Fatty Liver Disease

(2010) Russell K. Soon et al.   GASTROENTEROLOGY

Endoplasmic reticulum stress in liver disease

(2010) Harmeet Malhi et al.   JOURNAL OF HEPATOLOGY

Steatosis in Mice Is Associated with Gender, Folate Intake, and Expression of Genes of One-Carbon Metabolism

(2010) Karen E. Christensen et al.   JOURNAL OF NUTRITION

Coupling global methylation and gene expression profiles reveal key pathophysiological events in liver injury induced by a methyl-deficient diet

(2010) Volodymyr P. Tryndyak et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Animal models of nonalcoholic fatty liver disease

(2010) Lionel Hebbard et al.   Nature Reviews Gastroenterology & Hepatology

Toxicogenetics: population-based testing of drug and chemical safety in mouse models

(2010) Ivan Rusyn et al.   PHARMACOGENOMICS

Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

(2009) A. H. Harrill et al.   GENOME RESEARCH

Differences in betaine-homocysteine methyltransferase expression, endoplasmic reticulum stress response, and liver injury between alcohol-fed mice and rats

(2009) Masao Shinohara et al.   HEPATOLOGY

Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet

(2009) Igor P. Pogribny et al.   JOURNAL OF HEPATOLOGY

HumanS-adenosylhomocysteine hydrolase: common gene sequence variation and functional genomic characterization

(2009) Qiping Feng et al.   JOURNAL OF NEUROCHEMISTRY

Population-Based Discovery of Toxicogenomics Biomarkers for Hepatotoxicity Using a Laboratory Strain Diversity Panel

(2009) Alison H. Harrill et al.   TOXICOLOGICAL SCIENCES

Involvement of CCAAT/enhancer binding protein-ß (C/EBPß) in epigenetic regulation of mouse methionine adenosyltransferase 1A gene expression

(2008) Reiko Ikeda et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mthfd1Is an Essential Gene in Mice and Alters Biomarkers of Impaired One-carbon Metabolism

(2008) Amanda J. MacFarlane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dissection of endoplasmic reticulum stress signaling in alcoholic and non-alcoholic liver injury

(2008) Cheng Ji   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet

(2008) Mary E. Rinella et al.   JOURNAL OF LIPID RESEARCH