Met degradation: more than one stone to shoot a receptor down

Degradation of the GAB1 adaptor by the ubiquitin–proteasome pathway hampers HGF/SF–MET signaling

(2011) Gautier Goormachtigh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

GGA3 Functions as a Switch to Promote Met Receptor Recycling, Essential for Sustained ERK and Cell Migration

(2011) Christine Anna Parachoniak et al.   DEVELOPMENTAL CELL

A direct role for Met endocytosis in tumorigenesis

(2011) Carine Joffre et al.   NATURE CELL BIOLOGY

Monovalency Unleashes the Full Therapeutic Potential of the DN-30 Anti-Met Antibody

(2010) Giovanni Pacchiana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Disintegrin and Metalloproteinase-10 (ADAM-10) Mediates DN30 Antibody-induced Shedding of the Met Surface Receptor

(2010) Florian Schelter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decorin Antagonizes Met Receptor Activity and Down-regulates β-Catenin and Myc Levels

(2010) Simone Buraschi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Failure to ubiquitinate c-Met leads to hyperactivation of mTOR signaling in a mouse model of autosomal dominant polycystic kidney disease

(2010) Shan Qin et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of MET by Gene Amplification or by Splice Mutations Deleting the Juxtamembrane Domain in Primary Resected Lung Cancers

(2010) Ryoichi Onozato et al.   Journal of Thoracic Oncology

Inhibition of Fatty Acid Synthase Suppresses c-Met Receptor Kinase and Induces Apoptosis in Diffuse Large B-Cell Lymphoma

(2010) S. Uddin et al.   MOLECULAR CANCER THERAPEUTICS

MET signalling: principles and functions in development, organ regeneration and cancer

(2010) Livio Trusolino et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dependence receptors: a new paradigm in cell signaling and cancer therapy

(2010) D Goldschneider et al.   ONCOGENE

Breakdown of endocytosis in the oncogenic activation of receptor tyrosine kinases

(2009) Jasmine V. Abella et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

MicroRNA-1/206 Targets c-Metand Inhibits Rhabdomyosarcoma Development

(2009) Dongsheng Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decorin is a novel antagonistic ligand of the Met receptor

(2009) Silvia Goldoni et al.   JOURNAL OF CELL BIOLOGY

Internalization and intracellular sorting of the EGF receptor: a model for understanding the mechanisms of receptor trafficking

(2009) I. H. Madshus et al.   JOURNAL OF CELL SCIENCE

Ligand-Mediated Dimerization of the Met Receptor Tyrosine Kinase by the Bacterial Invasion Protein InlB

(2009) Davide M. Ferraris et al.   JOURNAL OF MOLECULAR BIOLOGY

Down-Regulation of the Met Receptor Tyrosine Kinase by Presenilin-dependent Regulated Intramembrane Proteolysis

(2009) Bénédicte Foveau et al.   MOLECULAR BIOLOGY OF THE CELL

Inhibition of fatty acid synthase by luteolin post-transcriptionally down-regulates c-Met expression independent of proteosomal/lysosomal degradation

(2009) D. T. Coleman et al.   MOLECULAR CANCER THERAPEUTICS

Tickets to ride: selecting cargo for clathrin-regulated internalization

(2009) Linton M. Traub   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Proteolytic cleavages give receptor tyrosine kinases the gift of ubiquity

(2009) F Ancot et al.   ONCOGENE

Caspase cleavage of the MET receptor generates an HGF interfering fragment

(2008) Julien Deheuninck et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNAs Impair MET-Mediated Invasive Growth

(2008) C. Migliore et al.   CANCER RESEARCH

Distinct Recruitment of Eps15 via Its Coiled-coil Domain Is Required For Efficient Down-regulation of the Met Receptor Tyrosine Kinase

(2008) Christine A. Parachoniak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Survival of the weakest: signaling aided by endosomes: Figure 1.

(2008) Marisa P. McShane et al.   JOURNAL OF CELL BIOLOGY

Receptor trafficking controls weak signal delivery: a strategy used by c-Met for STAT3 nuclear accumulation

(2008) Stéphanie Kermorgant et al.   JOURNAL OF CELL BIOLOGY