标题
Molecular mechanisms underlying chemical liver injury
作者
关键词
-
出版物
EXPERT REVIEWS IN MOLECULAR MEDICINE
Volume 14, Issue -, Pages -
出版商
Cambridge University Press (CUP)
发表日期
2012-02-03
DOI
10.1017/s1462399411002110
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Managing alcohol dependence and alcohol-related liver disease: a problem for the hepatologist, psychiatrist or economist?
- (2013) M. A. Stubbs et al. CLINICAL MEDICINE
- Overview of lipid peroxidation products and hepatic protein modification in alcoholic liver disease
- (2011) Rebecca L. Smathers et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Lysosomal Proteolysis Is the Primary Degradation Pathway for Cytosolic Ferritin and Cytosolic Ferritin Degradation Is Necessary for Iron Exit
- (2010) Yinghui Zhang et al. ANTIOXIDANTS & REDOX SIGNALING
- Linking long-term toxicity of xeno-chemicals with short-term biological adaptation
- (2010) Robert Barouki BIOCHIMIE
- Role of Human GlutathioneS-Transferases in the Inactivation of Reactive Metabolites of Clozapine
- (2010) Sanja Dragovic et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Risk assessment and mitigation strategies for reactive metabolites in drug discovery and development
- (2010) Richard A. Thompson et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Handling reactive metabolite positives in drug discovery: What has retrospective structure–toxicity analyses taught us?
- (2010) Amit S. Kalgutkar CHEMICO-BIOLOGICAL INTERACTIONS
- Pathology of Immune-Mediated Liver Injury
- (2010) Hans-Peter Dienes et al. DIGESTIVE DISEASES
- Involvement of the Immune System in Idiosyncratic Drug Reactions
- (2010) Xiachu Zhang et al. Drug Metabolism and Pharmacokinetics
- Cytochrome P450 regulation: the interplay between its heme and apoprotein moieties in synthesis, assembly, repair, and disposal
- (2010) Maria Almira Correia et al. DRUG METABOLISM REVIEWS
- Reactive oxygen species, cellular redox systems, and apoptosis
- (2010) Magdalena L. Circu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Drug-induced acute liver failure: Results of a U.S. multicenter, prospective study
- (2010) Adrian Reuben et al. HEPATOLOGY
- The DNA Damage Response: Making It Safe to Play with Knives
- (2010) Alberto Ciccia et al. MOLECULAR CELL
- Mechanisms of Pathogenesis in Drug Hepatotoxicity Putting the Stress on Mitochondria
- (2010) D. P. Jones et al. MOLECULAR INTERVENTIONS
- A map of human genome variation from population-scale sequencing
- (2010) Richard M. Durbin et al. NATURE
- Drug-induced liver injury: past, present and future
- (2010) Ann K Daly PHARMACOGENOMICS
- Hepatocyte Death: A Clear and Present Danger
- (2010) Harmeet Malhi et al. PHYSIOLOGICAL REVIEWS
- Genetic Determinants of Drug-induced Cholestasis and Intrahepatic Cholestasis of Pregnancy
- (2010) Christiane Pauli-Magnus et al. SEMINARS IN LIVER DISEASE
- The Role of Inflammation in Cholestasis: Clinical and Basic Aspects
- (2010) Astrid Kosters et al. SEMINARS IN LIVER DISEASE
- Apoptosis as a Mechanism for Liver Disease Progression
- (2010) Maria Eugenia Guicciardi et al. SEMINARS IN LIVER DISEASE
- Cell Death Mechanisms and Their Implications in Toxicology
- (2010) Sten Orrenius et al. TOXICOLOGICAL SCIENCES
- Mechanisms of Immune-Mediated Liver Injury
- (2010) David H. Adams et al. TOXICOLOGICAL SCIENCES
- Aflatoxin: A 50-Year Odyssey of Mechanistic and Translational Toxicology
- (2010) T. W. Kensler et al. TOXICOLOGICAL SCIENCES
- Chemical Biology of Peroxynitrite: Kinetics, Diffusion, and Radicals
- (2009) Gerardo Ferrer-Sueta et al. ACS Chemical Biology
- Oxidized Mitochondrial Protein Degradation and Repair in Aging and Oxidative Stress
- (2009) Nicolas Ugarte et al. ANTIOXIDANTS & REDOX SIGNALING
- Involvement of thio-, peroxi-, and glutaredoxins in cellular redox-dependent processes
- (2009) E. V. Kalinina et al. BIOCHEMISTRY-MOSCOW
- Nrf2 plays an important role in coordinated regulation of Phase II drug metabolism enzymes and Phase III drug transporters
- (2009) Guoxiang Shen et al. BIOPHARMACEUTICS & DRUG DISPOSITION
- Metabolites in Safety Testing (MIST): Considerations of Mechanisms of Toxicity with Dose, Abundance, and Duration of Treatment
- (2009) Dennis A. Smith et al. CHEMICAL RESEARCH IN TOXICOLOGY
- The Biochemistry of Drug Metabolism - An Introduction
- (2009) Bernard Testa et al. CHEMISTRY & BIODIVERSITY
- The effects of splicing variant of PXR PAR-2 on CYP3A4 and MDR1 mRNA expressions
- (2009) Yan Liu et al. CLINICA CHIMICA ACTA
- Pharmacokinetics of Acetaminophen-Protein Adducts in Adults with Acetaminophen Overdose and Acute Liver Failure
- (2009) L. P. James et al. DRUG METABOLISM AND DISPOSITION
- Acetaminophen Hepatotoxicity and Acute Liver Failure
- (2009) Linda J. Chun et al. JOURNAL OF CLINICAL GASTROENTEROLOGY
- Toward an “omic” physiopathology of reactive chemicals: Thirty years of mass spectrometric study of the protein adducts with endogenous and xenobiotic compounds
- (2009) Federico Maria Rubino et al. MASS SPECTROMETRY REVIEWS
- Interplay of Transporters and Enzymes in Drug and Metabolite Processing
- (2009) K. Sandy Pang et al. MOLECULAR PHARMACEUTICS
- Cytoplasmic functions of the tumour suppressor p53
- (2009) Douglas R. Green et al. NATURE
- HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin
- (2009) Ann K Daly et al. NATURE GENETICS
- Transduction of Redox Signaling by Electrophile-Protein Reactions
- (2009) T. K. Rudolph et al. Science Signaling
- Microanatomy of the liver immune system
- (2009) Eszter Nemeth et al. Seminars in Immunopathology
- Alcohol-induced Modulation of Signaling Pathways in Liver Parenchymal and Nonparenchymal Cells: Implications for Immunity
- (2009) Bharath Nath et al. SEMINARS IN LIVER DISEASE
- Oxidative Stress and Alcoholic Liver Disease
- (2009) Defeng Wu et al. SEMINARS IN LIVER DISEASE
- Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation
- (2008) Ulrich M. Zanger et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Inhibition and induction of human cytochrome P450 enzymes: current status
- (2008) Olavi Pelkonen et al. ARCHIVES OF TOXICOLOGY
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- Regulation of proteasome-mediated protein degradation during oxidative stress and aging
- (2008) Nicolle Breusing et al. BIOLOGICAL CHEMISTRY
- The Biochemistry of Drug Metabolism - An Introduction
- (2008) Bernard Testa et al. CHEMISTRY & BIODIVERSITY
- Drugs Behave as Substrates, Inhibitors and Inducers of Human Cytochrome P450 3A4
- (2008) Shu-Feng Zhou CURRENT DRUG METABOLISM
- Unique Transcription Start Sites and Distinct Promoter Regions Differentiate the Pregnane X Receptor (PXR) Isoforms PXR 1 and PXR 2
- (2008) L. M. Tompkins et al. DRUG METABOLISM AND DISPOSITION
- Interplay of conjugating enzymes with OATP uptake transporters and ABCC/MRP efflux pumps in the elimination of drugs
- (2008) Anne T Nies et al. Expert Opinion on Drug Metabolism & Toxicology
- Glutathione and apoptosis
- (2008) Magdalena L. Circu et al. FREE RADICAL RESEARCH
- Glutathione: Overview of its protective roles, measurement, and biosynthesis
- (2008) Henry Jay Forman et al. MOLECULAR ASPECTS OF MEDICINE
- Glutathione in liver diseases and hepatotoxicity
- (2008) Liyun Yuan et al. MOLECULAR ASPECTS OF MEDICINE
- Regulation of glutathione synthesis
- (2008) Shelly C. Lu MOLECULAR ASPECTS OF MEDICINE
- Bile acid transporters in health and disease
- (2008) A. Kosters et al. XENOBIOTICA
- Idiosyncratic Drug Reactions: Past, Present, and Future
- (2007) Jack Uetrecht CHEMICAL RESEARCH IN TOXICOLOGY
- Protein Damage by Reactive Electrophiles: Targets and Consequences
- (2007) Daniel C. Liebler CHEMICAL RESEARCH IN TOXICOLOGY
- 4-Hydroxynonenal–protein adducts: A reliable biomarker of lipid oxidation in liver diseases
- (2007) Giuseppe Poli et al. MOLECULAR ASPECTS OF MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started