Variation at the TERT locus and predisposition for cancer

Telomerase-Based Pharmacologic Enhancement of Antiviral Function of Human CD8+ T Lymphocytes

(2014) S. R. Fauce et al.   JOURNAL OF IMMUNOLOGY

The Epidemiology of Human Telomeres: Faults and Promises

(2011) A. Aviv   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33

(2010) Gloria M Petersen et al.   NATURE GENETICS

A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma

(2009) Maria Teresa Landi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Short Telomeres Resulting from Heritable Mutations in the Telomerase Reverse Transcriptase Gene Predispose for a Variety of Malignancies

(2009) Mark Hills et al.   Annals of the New York Academy of Sciences

Dyskeratosis congenita, stem cells and telomeres

(2009) Michael Kirwan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells

(2009) R. T. Calado et al.   BLOOD

Cancer in dyskeratosis congenita

(2009) B. P. Alter et al.   BLOOD

Polymorphisms in Telomere Maintenance Genes and Risk of Lung Cancer

(2009) J. E. Choi et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

A functional promoter polymorphism in the TERT gene does not affect inherited susceptibility to breast cancer

(2009) Verena Varadi et al.   CANCER GENETICS AND CYTOGENETICS

Deciphering the Impact of Common Genetic Variation on Lung Cancer Risk: A Genome-Wide Association Study

(2009) P. Broderick et al.   CANCER RESEARCH

Telomere Length in Peripheral Blood Predicts Survival in Clear Cell Renal Cell Carcinoma

(2009) U. Svenson et al.   CANCER RESEARCH

The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct formation in the lung

(2009) S. Zienolddiny et al.   CARCINOGENESIS

Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers

(2009) Y. Wang et al.   CARCINOGENESIS

Ets2 transcription factor, telomerase activity and breast cancer

(2009) Julie M Dwyer et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Mechanisms of telomeric instability

(2009) D.M. Baird   CYTOGENETIC AND GENOME RESEARCH

Short telomeres are preferentially elongated by telomerase in human cells

(2009) Bethan Britt-Compton et al.   FEBS LETTERS

Defining the pathogenic role of telomerase mutations in myelodysplastic syndrome and acute myeloid leukemia

(2009) Michael Kirwan et al.   HUMAN MUTATION

MNS16A minisatellite genotypes in relation to risk of glioma and meningioma and to glioblastoma outcome

(2009) Ulrika Andersson et al.   INTERNATIONAL JOURNAL OF CANCER

A genome-wide association study identifies a novel locus on chromosome 18q12.2 influencing white cell telomere length

(2009) M Mangino et al.   JOURNAL OF MEDICAL GENETICS

New common variants affecting susceptibility to basal cell carcinoma

(2009) Simon N Stacey et al.   NATURE GENETICS

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

(2009) Thorunn Rafnar et al.   NATURE GENETICS

Genome-wide association study identifies five susceptibility loci for glioma

(2009) Sanjay Shete et al.   NATURE GENETICS

Fusion of short telomeres in human cells is characterized by extensive deletion and microhomology, and can result in complex rearrangements

(2009) Boitelo T. Letsolo et al.   NUCLEIC ACIDS RESEARCH

Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia

(2009) R. T. Calado et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Human Telomerase Holoenzyme Protein Required for Cajal Body Localization and Telomere Synthesis

(2009) A. S. Venteicher et al.   SCIENCE

The Individual Blood Cell Telomere Attrition Rate Is Telomere Length Dependent

(2009) Katarina Nordfjäll et al.   PLoS Genetics

Characterization of primitive hematopoietic cells from patients with dyskeratosis congenita

(2008) F. D. Goldman et al.   BLOOD

Inherited aplastic anaemias/bone marrow failure syndromes

(2008) Inderjeet Dokal et al.   BLOOD REVIEWS

Prognostic molecular markers with no impact on decision-making: the paradox of gliomas based on a prospective study

(2008) M Wager et al.   BRITISH JOURNAL OF CANCER

Circulating haematopoietic progenitors are differentially reduced amongst subtypes of dyskeratosis congenita

(2008) Michael Kirwan et al.   BRITISH JOURNAL OF HAEMATOLOGY

Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer

(2008) Ji Un Kang et al.   CANCER GENETICS AND CYTOGENETICS

Breast Cancer Survival Is Associated with Telomere Length in Peripheral Blood Cells

(2008) U. Svenson et al.   CANCER RESEARCH

Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells

(2008) Ying Cao et al.   CANCER SCIENCE

Understanding and exploitinghTERTpromoter regulation for diagnosis and treatment of human cancers

(2008) Satoru Kyo et al.   CANCER SCIENCE

Basal cells have longest telomeres measured by tissue Q-FISH method in lingual epithelium

(2008) Junko Aida et al.   EXPERIMENTAL GERONTOLOGY

Genomic copy number alterations as predictive markers of systemic recurrence in breast cancer

(2008) Ki-Tae Hwang et al.   INTERNATIONAL JOURNAL OF CANCER

A Prospective Study of Telomere Length and the Risk of Skin Cancer

(2008) Jiali Han et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

(2008) Thorgeir E. Thorgeirsson et al.   NATURE

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

(2008) Rayjean J. Hung et al.   NATURE

Common 5p15.33 and 6p21.33 variants influence lung cancer risk

(2008) Yufei Wang et al.   NATURE GENETICS

Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21

(2008) Albert Tenesa et al.   NATURE GENETICS

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

(2008) Christopher I Amos et al.   NATURE GENETICS

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

(2008) Ian PM Tomlinson et al.   NATURE GENETICS

Lung cancer susceptibility locus at 5p15.33

(2008) James D McKay et al.   NATURE GENETICS

Telomere dynamics in human cells

(2007) Duncan M. Baird   BIOCHIMIE