mRNA vaccination as a safe approach for specific protection from type I allergy

Immunological mechanisms of allergen-specific immunotherapy

(2011) M. Jutel et al.   ALLERGY

MVA and NYVAC as Vaccines against Emergent Infectious Diseases and Cancer

(2011) Carmen E. Gomez et al.   CURRENT GENE THERAPY

Mechanisms of allergen-specific immunotherapy

(2011) Cezmi A. Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TLR agonist mediated suppression of allergic responses is associated with increased innate inflammation in the airways

(2011) Matthias J. Duechs et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Protein expression from exogenous mRNA: Uptake by receptor-mediated endocytosis and trafficking via the lysosomal pathway

(2011) Christina Lorenz et al.   RNA Biology

Neonatal colonization of mice with Lactobacillus plantarum producing the aeroallergen Bet v 1 biases towards Th1 and T-regulatory responses upon systemic sensitization

(2010) M. Schwarzer et al.   ALLERGY

Association of polymorphisms of toll-like receptor 4 with a reduced prevalence of hay fever and atopy

(2010) Ambikaipakan Senthilselvan et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Intranodal Vaccination with Naked Antigen-Encoding RNA Elicits Potent Prophylactic and Therapeutic Antitumoral Immunity

(2010) S. Kreiter et al.   CANCER RESEARCH

Developments in allergen-specific immunotherapy: from allergen extracts to allergy vaccines bypassing allergen-specific immunoglobulin E and T cell reactivity

(2010) M. Focke et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The current state of recombinant allergens for immunotherapy

(2010) Gabrielle Pauli et al.   Current Opinion in Allergy and Clinical Immunology

Prophylactic mRNA vaccination against allergy

(2010) Richard Weiss et al.   Current Opinion in Allergy and Clinical Immunology

Probiotic Escherichia coli Nissle 1917 activates DC and prevents house dust mite allergy through a TLR4-dependent pathway

(2010) Emmanuelle Adam et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo

(2010) A N Kuhn et al.   GENE THERAPY

Arabinogalactan isolated from cowshed dust extract protects mice from allergic airway inflammation and sensitization

(2010) Marcus Peters et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Designing hypoallergenic derivatives for allergy treatment by means of in silico mutation and screening

(2010) Theresa Thalhamer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

mRNA as gene therapeutic: How to control protein expression

(2010) Geertrui Tavernier et al.   JOURNAL OF CONTROLLED RELEASE

Birch Pollen Immunotherapy Leads to Differential Induction of Regulatory T Cells and Delayed Helper T Cell Immune Deviation

(2010) Christian Möbs et al.   JOURNAL OF IMMUNOLOGY

Messenger RNA-based Vaccines With Dual Activity Induce Balanced TLR-7 Dependent Adaptive Immune Responses and Provide Antitumor Activity

(2010) Mariola Fotin-Mleczek et al.   JOURNAL OF IMMUNOTHERAPY

Intradermal Vaccinations With RNA Coding for TAA Generate CD8+ and CD4+ Immune Responses and Induce Clinical Benefit in Vaccinated Patients

(2010) Susanne M Rittig et al.   MOLECULAR THERAPY

High levels of grass pollen inside European dairy farms: a role for the allergy-protective effects of environment?

(2009) B. Sudre et al.   ALLERGY

Prolonged antigen-exposure with carbohydrate particle based vaccination prevents allergic immune responses in sensitized mice

(2009) S. Thunberg et al.   ALLERGY

Probiotic Escherichia coli Nissle 1917 Suppresses Allergen-Induced Th2 Responses in the Airways

(2009) Thomas Bickert et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

An interaction between filaggrin mutations and early food sensitization improves the prediction of childhood asthma

(2009) Ingo Marenholz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Immunize and disappear—Safety-optimized mRNA vaccination with a panel of 29 allergens

(2009) Elisabeth Roesler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Direct Injection of Protamine-protected mRNA: Results of a Phase 1/2 Vaccination Trial in Metastatic Melanoma Patients

(2009) Benjamin Weide et al.   JOURNAL OF IMMUNOTHERAPY

UTRdb and UTRsite (RELEASE 2010): a collection of sequences and regulatory motifs of the untranslated regions of eukaryotic mRNAs

(2009) Giorgio Grillo et al.   NUCLEIC ACIDS RESEARCH

Immunomodulatory properties ofLactobacillus plantarumand its use as a recombinant vaccine against mite allergy

(2008) P. Rigaux et al.   ALLERGY

Intranasal vaccination with poly(lactide-co-glycolide) microparticles containing a peptide T of Ole e 1 prevents mice against sensitization

(2008) E. G. Marazuela et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Clinical effects of immunotherapy with genetically modified recombinant birch pollen Bet v 1 derivatives

(2008) A. Purohit et al.   CLINICAL AND EXPERIMENTAL ALLERGY

DNA vaccines for the prevention and treatment of allergy

(2008) Kaw Yan Chua et al.   Current Opinion in Allergy and Clinical Immunology

IL-5 and eosinophilia

(2008) Kiyoshi Takatsu et al.   CURRENT OPINION IN IMMUNOLOGY

Role of TLR3 in the immunogenicity of replicon plasmid-based vaccines

(2008) S S Diebold et al.   GENE THERAPY

Animal shed Bacillus licheniformis spores possess allergy-protective as well as inflammatory properties

(2008) Kay Vogel et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cord blood allergen-specific IgE is associated with reduced IFN-γ production by cord blood cells: The Protection against Allergy—Study in Rural Environments (PASTURE) study

(2008) Petra Ina Pfefferle et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

In vivo switch to IL-10–secreting T regulatory cells in high dose allergen exposure

(2008) Flurina Meiler et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Vaccination with a Modified Vaccinia Virus Ankara-based vaccine protects mice from allergic sensitization

(2008) Melanie Albrecht et al.   JOURNAL OF GENE MEDICINE

Results of the First Phase I/II Clinical Vaccination Trial With Direct Injection of mRNA

(2008) Benjamin Weide et al.   JOURNAL OF IMMUNOTHERAPY

Plasmid DNA- and messenger RNA-based anti-cancer vaccination

(2007) Benjamin Weide et al.   IMMUNOLOGY LETTERS