标题
Therapeutic potential of tyrosine kinase 2 in autoimmunity
作者
关键词
-
出版物
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 18, Issue 5, Pages 571-580
出版商
Informa Healthcare
发表日期
2014-03-21
DOI
10.1517/14728222.2014.892925
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Tyk2-Signaling Plays an Important Role in Host Defense against Escherichia coli through IL-23-Induced IL-17 Production by T Cells
- (2014) R. Nakamura et al. JOURNAL OF IMMUNOLOGY
- Lack of association between tyrosine kinase 2 (TYK2) gene polymorphisms and susceptibility to SLE in a Japanese population
- (2014) Chieko Kyogoku et al. Modern Rheumatology
- Mesenchymal stem cells from periapical lesions modulate differentiation and functional properties of monocyte-derived dendritic cells
- (2013) Jelena Đokić et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- NK Cells in Central Nervous System Disorders
- (2013) A. Poli et al. JOURNAL OF IMMUNOLOGY
- Two Rare Disease-Associated Tyk2 Variants Are Catalytically Impaired but Signaling Competent
- (2013) Z. Li et al. JOURNAL OF IMMUNOLOGY
- A Restricted Role for TYK2 Catalytic Activity in Human Cytokine Responses Revealed by Novel TYK2-Selective Inhibitors
- (2013) S. J. Sohn et al. JOURNAL OF IMMUNOLOGY
- The influence of non-HLA gene polymorphisms and interactions on disease risk in a Western Australian multiple sclerosis cohort
- (2013) Wei Qiu et al. JOURNAL OF NEUROIMMUNOLOGY
- Oleanolic acid suppresses resistin induction in adipocytes by modulating Tyk-STAT signaling
- (2013) Hyun-Sung Kim et al. NUTRITION RESEARCH
- Docking protein Gab2 regulates mucin expression and goblet cell hyperplasia through TYK2/STAT6 pathway
- (2012) Xue Zhang et al. FASEB JOURNAL
- IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages
- (2012) Ashish Bhattacharjee et al. FREE RADICAL BIOLOGY AND MEDICINE
- From Macrophage Interleukin-13 Receptor to Foam Cell Formation
- (2012) Valentin P. Yakubenko et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Induction of Antitumor Immunity Ex Vivo Using Dendritic Cells Transduced With Fowl Pox Vector Expressing MUC1, CEA, and a Triad of Costimulatory Molecules (rF-PANVAC)
- (2012) Baldev Vasir et al. JOURNAL OF IMMUNOTHERAPY
- Unknown
- (2012) Fernando Souza-Fonseca-Guimaraes et al. MOLECULAR MEDICINE
- Exome sequencing identifies a novel multiple sclerosis susceptibility variant in the TYK2 gene
- (2012) D. A. Dyment et al. NEUROLOGY
- TYK2 Kinase Activity Is Required for Functional Type I Interferon Responses In Vivo
- (2012) Michaela Prchal-Murphy et al. PLoS One
- Aberrant CD40-Induced NF-κB Activation in Human Lupus B Lymphocytes
- (2012) Wen Zhang et al. PLoS One
- STAT1-DEFICIENT MICE ARE RESISTANT TO CECAL LIGATION AND PUNCTURE–INDUCED SEPTIC SHOCK
- (2012) Daniela Herzig et al. SHOCK
- Replication of recently identified systemic lupus erythematosus genetic associations: a case–control study
- (2012) Marian Suarez-Gestal et al. ARTHRITIS RESEARCH & THERAPY
- Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor
- (2012) Maria A Argiriadi et al. BMC STRUCTURAL BIOLOGY
- Analysis of the mitochondrial proteome in multiple sclerosis cortex
- (2011) Laurie Broadwater et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Tyrosine kinase 2 variant influences T lymphocyte polarization and multiple sclerosis susceptibility
- (2011) N. Couturier et al. BRAIN
- Protective Role of Naturally Occurring Interleukin-17A-Producing γδ T Cells in the Lung at the Early Stage of Systemic Candidiasis in Mice
- (2011) Takashi Dejima et al. INFECTION AND IMMUNITY
- Tyk2 deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice
- (2011) M. Ishizaki et al. INTERNATIONAL IMMUNOLOGY
- Defective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells
- (2011) Masako Saito et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Noncanonical K27-Linked Polyubiquitination of TIEG1 Regulates Foxp3 Expression and Tumor Growth
- (2011) D.-J. Peng et al. JOURNAL OF IMMUNOLOGY
- Involvement of Tyrosine Kinase-2 in Both the IL-12/Th1 and IL-23/Th17 Axes In Vivo
- (2011) M. Ishizaki et al. JOURNAL OF IMMUNOLOGY
- Lack of Association of TYK2 Gene Polymorphisms in Chinese Patients with Systemic Lupus Erythematosus
- (2011) P. LI et al. JOURNAL OF RHEUMATOLOGY
- Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus
- (2011) Deborah S. Cunninghame Graham et al. PLoS Genetics
- Tyrosine kinase 2 interacts with the proapoptotic protein Siva-1 and augments its apoptotic functions
- (2010) Haruko K. Shimoda et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- IFN-γ activated JAK1 shifts CD40-induced cytokine profiles in human antigen-presenting cells toward high IL-12p70 and low IL-10 production
- (2010) Michael Conzelmann et al. BIOCHEMICAL PHARMACOLOGY
- Octamer-binding factor 6 (Oct-6/Pou3f1) is induced by interferon and contributes to dsRNA-mediated transcriptional responses
- (2010) Elisabeth Hofmann et al. BMC CELL BIOLOGY
- Transcriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes
- (2010) Claus Vogl et al. BMC GENOMICS
- Deficient SOCS3 and SHP-1 Expression in Psoriatic T Cells
- (2010) Karsten W. Eriksen et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6
- (2010) Jill E. Chrencik et al. JOURNAL OF MOLECULAR BIOLOGY
- A Proteomic Investigation of B Lymphocytes in an Autistic Family: A Pilot Study of Exposure to Natural Rubber Latex (NRL) May Lead to Autism
- (2010) Chen Shen et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Gene expression in IFNß signalling pathway differs between monocytes, CD4 and CD8 T cells from MS patients
- (2010) B. Oliver-Martos et al. JOURNAL OF NEUROIMMUNOLOGY
- The kinase inhibitory region of SOCS-1 is sufficient to inhibit T-helper 17 and other immune functions in experimental allergic encephalomyelitis
- (2010) Lindsey D. Jager et al. JOURNAL OF NEUROIMMUNOLOGY
- A new regulatory switch in a JAK protein kinase
- (2010) Vickie Tsui et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Lack of replication of genetic predictors for the rheumatoid arthritis response to anti-TNF treatments: a prospective case-only study
- (2010) Marian Suarez-Gestal et al. ARTHRITIS RESEARCH & THERAPY
- Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor
- (2009) Maria Ban et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis
- (2009) Inger-Lise Mero et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Tyrosine kinase 2 and interferon regulatory factor 5 polymorphisms are associated with discoid and subacute cutaneous lupus erythematosus
- (2009) Tiina M. Järvinen et al. EXPERIMENTAL DERMATOLOGY
- Janus kinases in immune cell signaling
- (2009) Kamran Ghoreschi et al. IMMUNOLOGICAL REVIEWS
- Strong Evidence of a Combination Polymorphism of the Tyrosine Kinase 2 Gene and the Signal Transducer and Activator of Transcription 3 Gene as a DNA-Based Biomarker for Susceptibility to Crohn’s Disease in the Japanese Population
- (2009) Kayoko Sato et al. JOURNAL OF CLINICAL IMMUNOLOGY
- PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
- (2009) Loise M. Francisco et al. JOURNAL OF EXPERIMENTAL MEDICINE
- An Unusual Insertion in Jak2 Is Crucial for Kinase Activity and Differentially Affects Cytokine Responses
- (2009) C. Haan et al. JOURNAL OF IMMUNOLOGY
- Tyrosine Kinase 2 Plays Critical Roles in the Pathogenic CD4 T Cell Responses for the Development of Experimental Autoimmune Encephalomyelitis
- (2009) A. Oyamada et al. JOURNAL OF IMMUNOLOGY
- Evidence for Genetic Association and Interaction Between the TYK2 and IRF5 Genes in Systemic Lupus Erythematosus
- (2009) A. HELLQUIST et al. JOURNAL OF RHEUMATOLOGY
- Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
- (2009) Melanie Bahlo et al. NATURE GENETICS
- The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes
- (2009) Chris Wallace et al. NATURE GENETICS
- PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling
- (2008) X. Lu et al. BLOOD
- Tumor-Induced Suppressor of Cytokine Signaling 3 Inhibits Toll-like Receptor 3 Signaling in Dendritic Cells via Binding to Tyrosine Kinase 2
- (2008) B. Zeng et al. CANCER RESEARCH
- Selective contribution of Tyk2 to cell activation by lipopolysaccharide
- (2008) Andrea Schneider et al. FEBS LETTERS
- Organ-specific and differential requirement of TYK2 and IFNAR1 for LPS-induced iNOS expression in vivo
- (2007) Ronald Painz et al. IMMUNOBIOLOGY
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