Defective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells

B cell–intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

(2010) Danielle T. Avery et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hyper-IgE syndrome

(2009) Yoshiyuki Minegishi   CURRENT OPINION IN IMMUNOLOGY

Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease

(2009) S. Brand   GUT

Regulatory T Cells in Asthma

(2009) Clare M. Lloyd et al.   IMMUNITY

Mechanisms and treatment of allergic disease in the big picture of regulatory T cells

(2009) Cezmi A. Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

(2009) Loise M. Francisco et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome

(2009) Yoshiyuki Minegishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

PD-1 and Its Ligands in Tolerance and Immunity

(2008) Mary E. Keir et al.   Annual Review of Immunology

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

(2008) Yuri P. Rubtsov et al.   IMMUNITY

Adaptive Foxp3+ Regulatory T Cell-Dependent and -Independent Control of Allergic Inflammation

(2008) Maria A. Curotto de Lafaille et al.   IMMUNITY

Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced TH17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome

(2008) Ellen D. Renner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Deficiency of Th17 cells in hyper IgE syndrome due to mutations inSTAT3

(2008) Cindy S. Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutations inSTAT3andIL12RB1impair the development of human IL-17–producing T cells

(2008) Ludovic de Beaucoudrey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

(2008) Joshua D. Milner et al.   NATURE

The IL-33/ST2 pathway: therapeutic target and novel biomarker

(2008) Rahul Kakkar et al.   NATURE REVIEWS DRUG DISCOVERY