Targeting the NMDA receptor subunit NR2B for treating or preventing age-related memory decline

Memory Enhancement by Targeting Cdk5 Regulation of NR2B

(2014) Florian Plattner et al.   NEURON

Magnesium supplement enhances spatial-context pattern separation and prevents fear overgeneralization

(2013) Nashat Abumaria et al.   BEHAVIOURAL PHARMACOLOGY

Elevation of Brain Magnesium Prevents and Reverses Cognitive Deficits and Synaptic Loss in Alzheimer's Disease Mouse Model

(2013) W. Li et al.   JOURNAL OF NEUROSCIENCE

Chronic dietary magnesium-L-threonate speeds extinction and reduces spontaneous recovery of a conditioned taste aversion

(2013) G. Andrew Mickley et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Mapping and Deciphering Neural Codes of NMDA Receptor-Dependent Fear Memory Engrams in the Hippocampus

(2013) Hongmiao Zhang et al.   PLoS One

Increased NR2A:NR2B ratio compresses long-term depression range and constrains long-term memory

(2013) Zhenzhong Cui et al.   Scientific Reports

Memory in aged mice is rescued by enhanced expression of the GluN2B subunit of the NMDA receptor

(2012) B.L. Brim et al.   BEHAVIOURAL BRAIN RESEARCH

Regulation of NMDA Receptor Transport: A KIF17-Cargo Binding/Releasing Underlies Synaptic Plasticity and Memory In Vivo

(2012) X. Yin et al.   JOURNAL OF NEUROSCIENCE

Genetic Overexpression of NR2B Subunit Enhances Social Recognition Memory for Different Strains and Species

(2012) Stephanie A. Jacobs et al.   PLoS One

Effects of Elevation of Brain Magnesium on Fear Conditioning, Fear Extinction, and Synaptic Plasticity in the Infralimbic Prefrontal Cortex and Lateral Amygdala

(2011) N. Abumaria et al.   JOURNAL OF NEUROSCIENCE

Presynaptic Induction and Expression of Timing-Dependent Long-Term Depression Demonstrated by Compartment-Specific Photorelease of a Use-Dependent NMDA Receptor Antagonist

(2011) A. Rodriguez-Moreno et al.   JOURNAL OF NEUROSCIENCE

Molecular Motor KIF17 Is Fundamental for Memory and Learning via Differential Support of Synaptic NR2A/2B Levels

(2011) Xiling Yin et al.   NEURON

Forebrain NR2B Overexpression Facilitating the Prefrontal Cortex Long-Term Potentiation and Enhancing Working Memory Function in Mice

(2011) Yihui Cui et al.   PLoS One

Cognition Enhancement Strategies

(2010) J. A. Bibb et al.   JOURNAL OF NEUROSCIENCE

Enhancement of Learning and Memory by Elevating Brain Magnesium

(2010) Inna Slutsky et al.   NEURON

A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone

(2010) S.-W. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Magnesium induces neuronal apoptosis by suppressing excitability

(2010) W H Dribben et al.   Cell Death & Disease

NMDA receptors mediate an early up-regulation of brain-derived neurotrophic factor expression in substantia nigra in a rat model of presymptomatic Parkinson's disease

(2009) Gonzalo Bustos et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Genetic Enhancement of Memory and Long-Term Potentiation but Not CA1 Long-Term Depression in NR2B Transgenic Rats

(2009) Deheng Wang et al.   PLoS One

Magnesium exerts both preventive and ameliorating effects in an in vitro rat Parkinson disease model involving 1-methyl-4-phenylpyridinium (MPP+) toxicity in dopaminergic neurons

(2008) Tomoyo Hashimoto et al.   BRAIN RESEARCH

Genetic enhancement of trace fear memory and cingulate potentiation in mice overexpressing Ca2+/calmodulin-dependent protein kinase IV

(2008) Long-Jun Wu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Upregulation of Calcium/Calmodulin-Dependent Protein Kinase IV Improves Memory Formation and Rescues Memory Loss with Aging

(2008) H. Fukushima et al.   JOURNAL OF NEUROSCIENCE