Several down, a few to go: histamine H3 receptor ligands making the final push towards the market?
出版年份 2011 全文链接
标题
Several down, a few to go: histamine H3 receptor ligands making the final push towards the market?
作者
关键词
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出版物
EXPERT OPINION ON INVESTIGATIONAL DRUGS
Volume 20, Issue 12, Pages 1629-1648
出版商
Informa Healthcare
发表日期
2011-11-18
DOI
10.1517/13543784.2011.625010
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- The histamine H3 receptor: from discovery to clinical trials with pitolisant
- (2011) Jean-Charles Schwartz BRITISH JOURNAL OF PHARMACOLOGY
- New H1/H3antagonists for treating allergic rhinitis: WO2010094643
- (2011) Peter Norman EXPERT OPINION ON THERAPEUTIC PATENTS
- The Discovery of Phthalazinone-Based Human H1and H3Single-Ligand Antagonists Suitable for Intranasal Administration for the Treatment of Allergic Rhinitis
- (2011) Panayiotis A. Procopiou et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structure of the human histamine H1 receptor complex with doxepin
- (2011) Tatsuro Shimamura et al. NATURE
- First, Second, and Third Generation Scalable Syntheses of Two Potent H3Antagonists
- (2011) Daniel J. Pippel et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Effect of a novel histamine subtype-3 receptor inverse agonist and modafinil on EEG power spectra during sleep deprivation and recovery sleep in male volunteers
- (2011) Lynette M. James et al. PSYCHOPHARMACOLOGY
- En route to new blockbuster anti-histamines: surveying the offspring of the expanding histamine receptor family
- (2011) Rob Leurs et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Histamine receptors in the CNS as targets for therapeutic intervention
- (2011) Maria Beatrice Passani et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: Identification of candidates for clinical development
- (2010) Michael A. Letavic et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Antinociceptive effects of histamine H3 receptor antagonist in the preclinical models of pain in rats and the involvement of central noradrenergic systems
- (2010) Gin C. Hsieh et al. BRAIN RESEARCH
- Acute Alertness-Promoting Effects of a Novel Histamine Subtype-3 Receptor Inverse Agonist in Healthy Sleep-Deprived Male Volunteers
- (2010) R Iannone et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Recent advances in histamine H3receptor antagonists/inverse agonists
- (2010) Dorota Łażewska et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Histamine H3Receptor as a Drug Discovery Target
- (2010) Michael Berlin et al. JOURNAL OF MEDICINAL CHEMISTRY
- Evaluation of 11C-GSK189254 as a Novel Radioligand for the H3 Receptor in Humans Using PET
- (2010) S. Ashworth et al. JOURNAL OF NUCLEAR MEDICINE
- Histamine and H3 Receptor in Alcohol-Related Behaviors
- (2010) P. Panula et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Discovery of Histamine H3 Antagonists for the Treatment of Cognitive Disorders and Alzheimer's Disease
- (2010) J. D. Brioni et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Modulation of prepulse inhibition and stereotypies in rodents: no evidence for antipsychotic-like properties of histamine H3-receptor inverse agonists
- (2010) Aude Burban et al. PSYCHOPHARMACOLOGY
- JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats
- (2010) Ruggero Galici et al. PSYCHOPHARMACOLOGY
- H 3 receptor antagonism increases methylhistamine levels in the cerebrospinal fluid of dogs and healthy human volunteers
- (2009) Holly Soares et al. Alzheimers & Dementia
- Differential effects of acute and repeat dosing with the H3 antagonist GSK189254 on the sleep-wake cycle and narcoleptic episodes in Ox−/− mice
- (2009) RX Guo et al. BRITISH JOURNAL OF PHARMACOLOGY
- Molecular and biochemical pharmacology of the histamine H4 receptor
- (2009) Rob Leurs et al. BRITISH JOURNAL OF PHARMACOLOGY
- Major advances in the development of histamine H4 receptor ligands
- (2009) Rogier A. Smits et al. DRUG DISCOVERY TODAY
- The histamine H3 receptor as a therapeutic drug target for CNS disorders
- (2009) Mark J. Gemkow et al. DRUG DISCOVERY TODAY
- Regional Differential Effects of the Novel Histamine H3 Receptor Antagonist 6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methyl-3-pyridinecarboxamide hydrochloride (GSK189254) on Histamine Release in the Central Nervous System of Freely Moving Rats
- (2009) P. Giannoni et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Histamine H3 Receptor Antagonists Go to Clinics
- (2008) Kerstin Sander et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Cloning and characterization of the monkey histamine H3 receptor isoforms
- (2008) Marina I. Strakhova et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Synthesis, Structure−Activity Relationships, and Biological Profiles of a Quinazolinone Class of Histamine H3Receptor Inverse Agonists
- (2008) Tsuyoshi Nagase et al. JOURNAL OF MEDICINAL CHEMISTRY
- Correlation between ex Vivo Receptor Occupancy and Wake-Promoting Activity of Selective H3 Receptor Antagonists
- (2008) S. Le et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Novel histamine H3 receptor antagonists GSK189254 and GSK334429 are efficacious in surgically-induced and virally-induced rat models of neuropathic pain
- (2008) Stephen J. Medhurst et al. PAIN
- An inverse agonist of the histamine H3 receptor improves wakefulness in narcolepsy: Studies in orexin−/− mice and patients
- (2007) Jian-Sheng Lin et al. NEUROBIOLOGY OF DISEASE
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