Interethnic variability ofCYP2D6alleles and of predicted and measured metabolic phenotypes across world populations

Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update

(2014) K R Crews et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Challenges in CYP2D6 Phenotype Assignment from Genotype Data: A Critical Assessment and Call for Standardization

(2014) J. Hicks et al.   CURRENT DRUG METABOLISM

CYP2D6 gene polymorphisms and predicted phenotypes in eight indigenous groups from northwestern Mexico

(2014) Blanca Patricia Lazalde-Ramos et al.   PHARMACOGENOMICS

Introduction of the AmpliChip CYP450 Test to a South African cohort: a platform comparative prospective cohort study

(2013) Tyren M Dodgen et al.   BMC Medical Genetics

High prevalence of CYP2D6*41 (G2988A) allele in Saudi Arabians

(2013) Mohammed S. Al-Dosari et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Characterization of CYP2D6 genotypes and metabolic profiles in the Portuguese population: pharmacogenetic implications

(2013) José Albuquerque et al.   Personalized Medicine

Pharmacogenetics in American Indian populations

(2013) Alison Fohner et al.   Pharmacogenetics and Genomics

Characterization of the CYP2D6 gene locus and metabolic activity in Indo- and Afro-Trinidadians: discovery of novel allelic variants

(2013) Lazara Karelia Montané Jaime et al.   PHARMACOGENOMICS

CYP2D6 -1584C>G promoter polymorphism and debrisoquine ultrarapid hydroxylation in healthy volunteers

(2013) Adrian LLerena et al.   PHARMACOGENOMICS

Genetic variations of human CYP2D6 in the Chinese Han population

(2013) Jian-Chang Qian et al.   PHARMACOGENOMICS

Ethiopian Genetic Diversity Reveals Linguistic Stratification and Complex Influences on the Ethiopian Gene Pool

(2012) Luca Pagani et al.   AMERICAN JOURNAL OF HUMAN GENETICS

CYP2D6 gene variants in urban/admixed and Amerindian populations of Venezuela: Pharmacogenetics and anthropological implications

(2012) Pedro Griman et al.   ANNALS OF HUMAN BIOLOGY

The frequencies of mutated alleles of CYP2D6 gene in a Turkish population

(2012) A. Serin et al.   FORENSIC SCIENCE INTERNATIONAL

Frequency of Certain Single-Nucleotide Polymorphisms and Duplication of CYP2D6 in the Jordanian Population

(2012) Malek Zihlif et al.   Genetic Testing and Molecular Biomarkers

Allele and Genotype Frequencies of CYP3A4, CYP2C19, and CYP2D6 in Han, Uighur, Hui, and Mongolian Chinese Populations

(2012) Liang Jin Zuo et al.   Genetic Testing and Molecular Biomarkers

Distribution of CYP2D6 and CYP2C19 Polymorphisms Associated with Poor Metabolizer Phenotype in Five Amerindian Groups and Western Mestizos from Mexico

(2012) Joel Salazar-Flores et al.   Genetic Testing and Molecular Biomarkers

CYP2D6 ultrarapid metabolism and early dropout from fluoxetine or amitriptyline monotherapy treatment in major depressive patients

(2012) E M Peñas-LLedó et al.   MOLECULAR PSYCHIATRY

More Codeine Fatalities After Tonsillectomy in North American Children

(2012) L. E. Kelly et al.   PEDIATRICS

The great human expansion

(2012) B. M. Henn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequencies of 23 Functionally Significant Variant Alleles Related with Metabolism of Antineoplastic Drugs in the Chilean Population: Comparison with Caucasian and Asian Populations

(2012) Ángela Roco et al.   Frontiers in Genetics

CYP2D6 genotyping by liquid chromatography-electrospray ionization mass spectrometry

(2011) Beate Beer et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Pilot study for the characterization of pharmacogenetically relevant CYP2D6, CYP2C19 and ABCB1 gene polymorphisms in the Hungarian population

(2011) Orsolya Rideg et al.   CELL BIOCHEMISTRY AND FUNCTION

Pharmacogenomics of CYP2D6: Molecular Genetics, Interethnic Differences and Clinical Importance

(2011) Lay Kek Teh et al.   Drug Metabolism and Pharmacokinetics

CYP2D6 genotype and dextromethorphan hydroxylation phenotype in an Ecuadorian population

(2011) Pedro Dorado et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Frequencies of Three CYP2D6 Nonfunctional Alleles (CYP2D6*3, *4, and *6) Within an Iranian Population (Mazandaran)

(2011) Seyed Mohammad Bagher Hashemi-Soteh et al.   Genetic Testing and Molecular Biomarkers

CYP2D6 Genotyping in Natives and Immigrants from the Emilia-Romagna Region (Italy)

(2011) Laura N. Riccardi et al.   Genetic Testing and Molecular Biomarkers

Differences in genotype and allele frequency distributions of polymorphic drug metabolizing enzymes CYP2C19 and CYP2D6 in mainland Chinese Mongolian, Hui and Han populations

(2011) S.-J. Yin et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

High risk of lifetime history of suicide attempts among CYP2D6 ultrarapid metabolizers with eating disorders

(2011) E M Peñas-Lledó et al.   MOLECULAR PSYCHIATRY

Resequencing, haplotype construction and identification of novel variants ofCYP2D6in Mexican Mestizos

(2011) Alejandra V Contreras et al.   PHARMACOGENOMICS

CYP2D6and the severity of suicide attempts

(2011) Eva M Peñas-Lledó et al.   PHARMACOGENOMICS

Identification of New Alleles and the Determination of Alleles and Genotypes Frequencies at the CYP2D6 Gene in Emiratis

(2011) Rula Y. Qumsieh et al.   PLoS One

Robust CYP2D6 genotype assay including copy number variation using multiplex single-base extension for Asian populations

(2010) Eun-Young Kim et al.   CLINICA CHIMICA ACTA

The Evolution of Human Genetic and Phenotypic Variation in Africa

(2010) Michael C. Campbell et al.   CURRENT BIOLOGY

Analysis of 50 SNPs in CYP2D6, CYP2C19, CYP2C9, CYP3A4 and CYP1A2 by MALDI-TOF mass spectrometry in Chinese Han population

(2010) Yan Shi et al.   FORENSIC SCIENCE INTERNATIONAL

Evolution of detoxifying systems: the role of environment and population history in shaping genetic diversity at human CYP2D6 locus

(2010) Silvia Fuselli et al.   Pharmacogenetics and Genomics

CYP2D6 polymorphism in patients with eating disorders

(2010) E M Peñas-LLedó et al.   PHARMACOGENOMICS JOURNAL

CYP2D6 genotype and debrisoquine hydroxylation phenotype in Cubans and Nicaraguans

(2010) A LLerena et al.   PHARMACOGENOMICS JOURNAL

Influence of CYP2D6 Deletion, Multiplication, –1584C→G, 31G→A and 2988G→A Gene Polymorphisms on Dextromethorphan Metabolism among Mexican Tepehuanos and Mestizos

(2010) Martha Sosa-Macías et al.   PHARMACOLOGY

Polymorphisms in genes encoding drugs and xenobiotic metabolizing enzymes in a Brazilian population

(2009) Vanessa Da Silva Silveira et al.   BIOMARKERS

Characterization of pharmacogenetically relevantCYP2D6andABCB1gene polymorphisms in a Portuguese population sample

(2009) C. Correia et al.   CELL BIOCHEMISTRY AND FUNCTION

High Frequency of Occurrence of CYP2D6 Gene Duplication/Multiduplication Indicating Ultrarapid Metabolism Among Suicide Cases

(2009) A L Zackrisson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Discovery of Novel Functional Variants and Extensive Evaluation of CYP2D6 Genetic Polymorphisms in Koreans

(2009) S.-J. Lee et al.   DRUG METABOLISM AND DISPOSITION

Frequency of Five Important CYP2D6 Alleles Within an Iranian Population (Eastern Azerbaijan)

(2009) Hamed Kouhi et al.   Genetic Testing and Molecular Biomarkers

Population analysis of xenobiotic metabolizing genes in South Brazilian Euro and Afro-descendants

(2009) Marcos Euzébio Maciel et al.   GENETICS AND MOLECULAR BIOLOGY

Codeine, Ultrarapid-Metabolism Genotype, and Postoperative Death

(2009) Catherine Ciszkowski et al.   NEW ENGLAND JOURNAL OF MEDICINE

Molecular diversity at theCYP2D6locus in healthy and schizophrenic southern Brazilians

(2009) Fabiana B Kohlrausch et al.   PHARMACOGENOMICS

Genetic polymorphism, linkage disequilibrium, haplotype structure and novel allele analysis of CYP2C19 and CYP2D6 in Han Chinese

(2009) Q Zhou et al.   PHARMACOGENOMICS JOURNAL

The CYP2D6 gene locus in South African Coloureds: unique allele distributions, novel alleles and gene arrangements

(2008) Andrea Gaedigk et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacogenomics of CYP2A6, CYP2B6, CYP2C19, CYP2D6, CYP3A4, CYP3A5 and MDR1 in Vietnam

(2008) M. I. Veiga et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Systematic polymorphism analysis of the CYP2D6 gene in four different geographical Han populations in mainland China

(2008) Shengying Qin et al.   GENOMICS

Pharmacogenetics of debrisoquine and its use as a marker for CYP2D6 hydroxylation capacity

(2008) Adrián LLerena et al.   PHARMACOGENOMICS

The AmpliChip CYP450 test: cytochrome P450 2D6 genotype assessment and phenotype prediction

(2008) M C Rebsamen et al.   PHARMACOGENOMICS JOURNAL

Surfing during population expansions promotes genetic revolutions and structuration

(2008) Laurent Excoffier et al.   TRENDS IN ECOLOGY & EVOLUTION