Sandwich-cultured hepatocytes: utility forin vitroexploration of hepatobiliary drug disposition and drug-induced hepatotoxicity
出版年份 2013 全文链接
标题
Sandwich-cultured hepatocytes: utility forin vitroexploration of hepatobiliary drug disposition and drug-induced hepatotoxicity
作者
关键词
-
出版物
Expert Opinion on Drug Metabolism & Toxicology
Volume 9, Issue 5, Pages 589-616
出版商
Informa Healthcare
发表日期
2013-03-02
DOI
10.1517/17425255.2013.773973
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Recovery of Mature Hepatocytic Phenotype following Bile Ductular Transdifferentiation of Rat Hepatocytes in Vitro
- (2012) Masayuki Sone et al. AMERICAN JOURNAL OF PATHOLOGY
- Tissue specific synthetic ECM hydrogels for 3-D in vitro maintenance of hepatocyte function
- (2012) Aleksander Skardal et al. BIOMATERIALS
- Suppression of Hepatocyte Proliferation by Hepatocyte Nuclear Factor 4α in Adult Mice
- (2012) Jessica A. Bonzo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Assessment of Biliary Clearance in Early Drug Discovery using Sandwich-cultured Hepatocyte Model
- (2012) Guoyu Pan et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Physiologically Based Modeling of Pravastatin Transporter-Mediated Hepatobiliary Disposition and Drug-Drug Interactions
- (2012) Manthena V. S. Varma et al. PHARMACEUTICAL RESEARCH
- Application of quantitative time-lapse imaging (QTLI) for evaluation of Mrp2-based drug–drug interaction induced by liver metabolites
- (2012) Takeo Nakanishi et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Novel insight into mechanisms of cholestatic liver injury
- (2012) Benjamin L Woolbright WORLD JOURNAL OF GASTROENTEROLOGY
- An ‘all-inclusive’ 96-well cytochrome P450 induction method: Measuring enzyme activity, mRNA levels, protein levels, and cytotoxicity from one well using cryopreserved human hepatocytes
- (2012) Jason S. Halladay et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Evaluation of metabolism-mediated herb-drug interactions
- (2011) Dong Hee Na et al. ARCHIVES OF PHARMACAL RESEARCH
- The Behaviors of Long-Term Cryopreserved Human Hepatocytes on Different Biomaterials
- (2011) Jui-Nan Lu et al. ARTIFICIAL ORGANS
- Bile salt export pump inhibitors are associated with bile acid-dependent drug-induced toxicity in sandwich-cultured hepatocytes
- (2011) Eiichiro Ogimura et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Screening of Antibiotics That Interact with Organic Anion-Transporting Polypeptides 1B1 and 1B3 Using Fluorescent Probes
- (2011) Hiroaki Yamaguchi et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Predicting Clearance in Humans from In Vitro Data
- (2011) R. Scott Obach CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Quantitative Time-Lapse Imaging-Based Analysis of Drug-Drug Interaction Mediated by Hepatobiliary Transporter, Multidrug Resistance-Associated Protein 2, in Sandwich-Cultured Rat Hepatocytes
- (2011) T. Nakanishi et al. DRUG METABOLISM AND DISPOSITION
- Effect of Culture Time on the Basal Expression Levels of Drug Transporters in Sandwich-Cultured Primary Rat Hepatocytes
- (2011) E. H. Tchaparian et al. DRUG METABOLISM AND DISPOSITION
- Complex Drug Interactions of HIV Protease Inhibitors 1: Inactivation, Induction, and Inhibition of Cytochrome P450 3A by Ritonavir or Nelfinavir
- (2011) B. J. Kirby et al. DRUG METABOLISM AND DISPOSITION
- Culture Period-Dependent Changes in the Uptake of Transporter Substrates in Sandwich-Cultured Rat and Human Hepatocytes
- (2011) N. Kotani et al. DRUG METABOLISM AND DISPOSITION
- Time-course activities of Oct1, Mrp3, and cytochrome P450s in cultures of cryopreserved rat hepatocytes
- (2011) Jacob Kramer Jacobsen et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- The stable repression of mesenchymal program is required for hepatocyte identity: A novel role for hepatocyte nuclear factor 4α
- (2011) Laura Santangelo et al. HEPATOLOGY
- Mechanisms Underlying Differences in Systemic Exposure of Structurally Similar Active Metabolites: Comparison of Two Preclinical Hepatic Models
- (2011) G. Z. Yan et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Novel In Vitro-In Vivo Extrapolation (IVIVE) Method to Predict Hepatic Organ Clearance in Rat
- (2011) Ken-ichi Umehara et al. PHARMACEUTICAL RESEARCH
- A Critical Analysis of the Interplay between Cytochrome P450 3A and P-Glycoprotein: Recent Insights from Knockout and Transgenic Mice
- (2011) R. A. B. van Waterschoot et al. PHARMACOLOGICAL REVIEWS
- Isolation of Primary Human Hepatocytes from Normal and Diseased Liver Tissue: A One Hundred Liver Experience
- (2011) Ricky H. Bhogal et al. PLoS One
- Differential Disposition of Chenodeoxycholic Acid versus Taurocholic Acid in Response to Acute Troglitazone Exposure in Rat Hepatocytes
- (2011) Tracy L. Marion et al. TOXICOLOGICAL SCIENCES
- Glutathione depletion by valproic acid in sandwich-cultured rat hepatocytes: Role of biotransformation and temporal relationship with onset of toxicity
- (2011) Tony K.L. Kiang et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Scaling In Vivo Pharmacokinetics from In Vitro Metabolic Stability Data in Drug Discovery
- (2010) Wendy Klopf et al. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
- Inhibition of Hepatic Organic Anion-Transporting Polypeptide by RNA Interference in Sandwich-Cultured Human Hepatocytes: An In Vitro Model to Assess Transporter-Mediated Drug-Drug Interactions
- (2010) M. Liao et al. DRUG METABOLISM AND DISPOSITION
- Estimation of Transporters Involved in the Hepatobiliary Transport of TA-0201CA Using Sandwich-Cultured Rat Hepatocytes from Normal and Multidrug Resistance-Associated Protein 2-Deficient Rats
- (2010) H. Fukuda et al. DRUG METABOLISM AND DISPOSITION
- In Vitro Investigation of the Hepatobiliary Disposition Mechanisms of the Antifungal Agent Micafungin in Humans and Rats
- (2010) S. B. Yanni et al. DRUG METABOLISM AND DISPOSITION
- Sandwich-cultured hepatocytes: anin vitromodel to evaluate hepatobiliary transporter-based drug interactions and hepatotoxicity
- (2010) Brandon Swift* et al. DRUG METABOLISM REVIEWS
- Sulindac and Its Metabolites Inhibit Multiple Transport Proteins in Rat and Human Hepatocytes
- (2010) J. K. Lee et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Improved Extrapolation of Hepatobiliary Clearance fromin VitroSandwich Cultured Rat Hepatocytes through Absolute Quantification of Hepatobiliary Transporters
- (2010) Na Li et al. MOLECULAR PHARMACEUTICS
- Evaluation of 99mTechnetium-Mebrofenin and 99mTechnetium-Sestamibi as Specific Probes for Hepatic Transport Protein Function in Rat and Human Hepatocytes
- (2010) Brandon Swift et al. PHARMACEUTICAL RESEARCH
- Role of Oxidative Metabolism in the Effect of Valproic Acid on Markers of Cell Viability, Necrosis, and Oxidative Stress in Sandwich-Cultured Rat Hepatocytes
- (2010) Tony K. L. Kiang et al. TOXICOLOGICAL SCIENCES
- Interference with Bile Salt Export Pump Function Is a Susceptibility Factor for Human Liver Injury in Drug Development
- (2010) Ryan E. Morgan et al. TOXICOLOGICAL SCIENCES
- LC−MS/MS Mediated Absolute Quantification and Comparison of Bile Salt Export Pump and Breast Cancer Resistance Protein in Livers and Hepatocytes across Species
- (2009) Na Li et al. ANALYTICAL CHEMISTRY
- Serum-free collagen sandwich cultures of adult rat hepatocytes maintain liver-like properties long term: A valuable model for in vitro toxicity and drug–drug interaction studies
- (2009) Gregor Tuschl et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Glucuronidation and Covalent Protein Binding of Benoxaprofen and Flunoxaprofen in Sandwich-Cultured Rat and Human Hepatocytes
- (2009) J. Q. Dong et al. DRUG METABOLISM AND DISPOSITION
- An In Vitro Assay to Assess Transporter-Based Cholestatic Hepatotoxicity Using Sandwich-Cultured Rat Hepatocytes
- (2009) J. H. Ansede et al. DRUG METABOLISM AND DISPOSITION
- Investigation of the Rate-Determining Process in the Hepatic Elimination of HMG-CoA Reductase Inhibitors in Rats and Humans
- (2009) T. Watanabe et al. DRUG METABOLISM AND DISPOSITION
- Species-Specific Interaction of HIV Protease Inhibitors With Accumulation of Cholyl-Glycylamido-Fluorescein (CGamF) in Sandwich-Cultured Hepatocytes
- (2009) Zhi-Wei Ye et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Hepatobiliary Disposition of Troglitazone and Metabolites in Rat and Human Sandwich-Cultured Hepatocytes: Use of Monte Carlo Simulations to Assess the Impact of Changes in Biliary Excretion on Troglitazone Sulfate Accumulation
- (2009) J. K. Lee et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Quantitative Expression Profile of Hepatobiliary Transporters in Sandwich Cultured Rat and Human Hepatocytes
- (2009) Na Li et al. MOLECULAR PHARMACEUTICS
- Interplay of Drug Metabolism and Transport: A Real Phenomenon or an Artifact of the Site of Measurement?
- (2009) Christopher J. Endres et al. MOLECULAR PHARMACEUTICS
- Influence of Seeding Density and Extracellular Matrix on Bile Acid Transport and Mrp4 Expression in Sandwich-Cultured Mouse Hepatocytes
- (2009) Brandon Swift et al. MOLECULAR PHARMACEUTICS
- Bile-acid-induced cell injury and protection
- (2009) Maria J Perez et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes
- (2008) Rajgopal Govindarajan et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- General Framework for the Prediction of Oral Drug Interactions Caused by CYP3A4 Induction from In Vivo Information
- (2008) Yoshiyuki Ohno et al. CLINICAL PHARMACOKINETICS
- Effect of Albumin on the Biliary Clearance of Compounds in Sandwich-Cultured Rat Hepatocytes
- (2008) K. K. Wolf et al. DRUG METABOLISM AND DISPOSITION
- Absolute Difference of Hepatobiliary Transporter Multidrug Resistance-Associated Protein (MRP2/Mrp2) in Liver Tissues and Isolated Hepatocytes from Rat, Dog, Monkey, and Human
- (2008) N. Li et al. DRUG METABOLISM AND DISPOSITION
- Effect of Plasma Protein Binding on in Vitro-in Vivo Correlation of Biliary Excretion of Drugs Evaluated by Sandwich-Cultured Rat Hepatocytes
- (2008) H. Fukuda et al. DRUG METABOLISM AND DISPOSITION
- Use of Sandwich-Cultured Human Hepatocytes to Predict Biliary Clearance of Angiotensin II Receptor Blockers and HMG-CoA Reductase Inhibitors
- (2008) K. Abe et al. DRUG METABOLISM AND DISPOSITION
- PREDICTION OF DRUG-DRUG INTERACTIONS FROM IN VITRO INDUCTION DATA: Application of the Relative Induction Score Approach Using Cryopreserved Human Hepatocytes
- (2008) O. A. Fahmi et al. DRUG METABOLISM AND DISPOSITION
- Drug-induced Hyperbilirubinemia and the Clinical Influencing Factors
- (2008) Young-Mi Ah et al. DRUG METABOLISM REVIEWS
- In Vitro Biliary Clearance of Angiotensin II Receptor Blockers and 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase Inhibitors in Sandwich-Cultured Rat Hepatocytes: Comparison with in Vivo Biliary Clearance
- (2008) K. Abe et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Clearance and clearance inhibition of the HIV-1 protease inhibitors ritonavir and saquinavir in sandwich-cultured rat hepatocytes and rat microsomes
- (2008) N. Treijtel et al. TOXICOLOGY IN VITRO
- Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells
- (2007) P Martin et al. BRITISH JOURNAL OF PHARMACOLOGY
- Modulation of sinusoidal and canalicular elimination of bilirubin-glucuronides by rifampicin and other cholestatic drugs in a sandwich culture of rat hepatocytes
- (2007) György Lengyel et al. HEPATOLOGY RESEARCH
- Modulation of trabectedin (ET-743) hepatobiliary disposition by multidrug resistance-associated proteins (Mrps) may prevent hepatotoxicity
- (2007) Jin Kyung Lee et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now