In silicomodels for drug-induced liver injury – current status

Predicting Drug-Induced Hepatotoxicity Using QSAR and Toxicogenomics Approaches

(2011) Yen Low et al.   CHEMICAL RESEARCH IN TOXICOLOGY

A review of the electrophilic reaction chemistry involved in covalent protein binding relevant to toxicity

(2011) S. J. Enoch et al.   CRITICAL REVIEWS IN TOXICOLOGY

A review of the use ofin silicomethods to predict the chemistry of molecular initiating events related to drug toxicity

(2011) Claire M Ellison et al.   Expert Opinion on Drug Metabolism & Toxicology

Assessment of Methods To Define the Applicability Domain of Structural Alert Models

(2011) C. M. Ellison et al.   Journal of Chemical Information and Modeling

Drug induced hepatotoxicity: data from the Serbian pharmacovigilance database

(2011) Marija Petronijevic et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Modeling Liver-Related Adverse Effects of Drugs UsingkNearest Neighbor Quantitative Structure−Activity Relationship Method

(2010) Amie D. Rodgers et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Developing Structure−Activity Relationships for the Prediction of Hepatotoxicity

(2010) Nigel Greene et al.   CHEMICAL RESEARCH IN TOXICOLOGY

A Predictive Ligand-Based Bayesian Model for Human Drug-Induced Liver Injury

(2010) S. Ekins et al.   DRUG METABOLISM AND DISPOSITION

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Using In Silico Tools in a Weight of Evidence Approach to Aid Toxicological Assessment

(2010) Claire M. Ellison et al.   Molecular Informatics

Biomarkers for drug-induced liver injury

(2010) Qiang Shi et al.   Expert Review of Gastroenterology & Hepatology

Cheminformatics Analysis of Assertions Mined from Literature That Describe Drug-Induced Liver Injury in Different Species

(2009) Denis Fourches et al.   CHEMICAL RESEARCH IN TOXICOLOGY

An Expert System Approach to the Assessment of Hepatotoxic Potential

(2009) Carol A. Marchant et al.   CHEMISTRY & BIODIVERSITY

In Silico Prediction of Hepatotoxicity

(2009) Ailan Cheng   Current Computer-Aided Drug Design

Current Concepts of Mechanisms in Drug-Induced Hepatotoxicity

(2009) Stefan Russmann et al.   CURRENT MEDICINAL CHEMISTRY

The patient presenting with isolated hyperbilirubinemia

(2009) L. Fabris et al.   DIGESTIVE AND LIVER DISEASE

Drug-Induced Liver Injury Network (DILIN) Prospective Study

(2009) Robert J. Fontana et al.   DRUG SAFETY

Human drug hepatotoxicity: a contemporary clinical perspective

(2009) David N Assis et al.   Expert Opinion on Drug Metabolism & Toxicology

Histological patterns in drug-induced liver disease

(2009) R Ramachandran et al.   JOURNAL OF CLINICAL PATHOLOGY

The Japanese toxicogenomics project: Application of toxicogenomics

(2009) Takeki Uehara et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Identification of structure–activity relationships for adverse effects of pharmaceuticals in humans. Part A: Use of FDA post-market reports to create a database of hepatobiliary and urinary tract toxicities

(2009) Carling J. Ursem et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Identification of structure-activity relationships for adverse effects of pharmaceuticals in humans: Part B. Use of (Q)SAR systems for early detection of drug-induced hepatobiliary and urinary tract toxicities

(2009) Edwin J. Matthews et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Identification of structure–activity relationships for adverse effects of pharmaceuticals in humans: Part C: Use of QSAR and an expert system for the estimation of the mechanism of action of drug-induced hepatobiliary and urinary tract toxicities

(2009) Edwin J. Matthews et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Integrating (Q)SAR models, expert systems and read-across approaches for the prediction of developmental toxicity

(2009) M. Hewitt et al.   REPRODUCTIVE TOXICOLOGY

Biomarkers for the Diagnosis and Management of Drug-Induced Liver Injury

(2009) Paul Watkins   SEMINARS IN LIVER DISEASE

In silico toxicology for the pharmaceutical sciences☆

(2009) Luis G. Valerio Jr.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Drug-induced liver injury: Is it somehow foreseeable?

(2009) Giovanni Tarantino et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The liver pharmacological and xenobiotic gene response repertoire

(2008) Georges Natsoulis et al.   Molecular Systems Biology

Structure alerts for carcinogenicity, and the Salmonella assay system: A novel insight through the chemical relational databases technology

(2008) R BENIGNI et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Category analysis of the substituted anilines studied in a 28-day repeat-dose toxicity test conducted on rats: Correlation between toxicity and chemical structure†

(2008) Y. Sakuratani et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury

(2008) Jinghai J. Xu et al.   TOXICOLOGICAL SCIENCES

Use of toxicogenomics to understand mechanisms of drug-induced hepatotoxicity during drug discovery and development

(2008) Eric A.G. Blomme et al.   TOXICOLOGY LETTERS

The current state of serum biomarkers of hepatotoxicity

(2007) Josef Ozer et al.   TOXICOLOGY