Alternatives to the carcinogenicity bioassay for toxicity prediction: are we there yet?
出版年份 2012 全文链接
标题
Alternatives to the carcinogenicity bioassay for toxicity prediction: are we there yet?
作者
关键词
-
出版物
Expert Opinion on Drug Metabolism & Toxicology
Volume 8, Issue 4, Pages 407-417
出版商
Informa Healthcare
发表日期
2012-02-23
DOI
10.1517/17425255.2012.666238
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The tissue organization field theory of cancer: A testable replacement for the somatic mutation theory
- (2011) Ana M. Soto et al. BIOESSAYS
- Mechanisms of Chemical Carcinogenicity and Mutagenicity: A Review with Implications for Predictive Toxicology
- (2011) Romualdo Benigni et al. CHEMICAL REVIEWS
- What Do Medicinal Chemists Actually Make? A 50-Year Retrospective
- (2011) W. Patrick Walters et al. JOURNAL OF MEDICINAL CHEMISTRY
- Cell transformation assays for prediction of carcinogenic potential: state of the science and future research needs
- (2011) S. Creton et al. MUTAGENESIS
- Alternative strategies for carcinogenicity assessment: an efficient and simplified approach based on in vitro mutagenicity and cell transformation assays
- (2011) R. Benigni et al. MUTAGENESIS
- The new ISSMIC database on in vivo micronucleus and its role in assessing genotoxicity testing strategies
- (2011) R. Benigni et al. MUTAGENESIS
- Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment
- (2010) Gerald T. Ankley et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
- Research on Early-Stage Carcinogenesis: Are We Approaching Paradigm Instability?
- (2010) Stuart G. Baker et al. JOURNAL OF CLINICAL ONCOLOGY
- Exploring In Vitro/In Vivo Correlation: Lessons Learned from Analyzing Phase I Results of the US EPA's ToxCast Project
- (2010) ROMUALDO BENIGNI et al. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS
- Toxic and genotoxic effects of oral administration of furan in mouse liver
- (2010) E. Cordelli et al. MUTAGENESIS
- A Medium-Term, Rapid Rat Bioassay Model for the Detection of Carcinogenic Potential of Chemicals
- (2010) Hiroyuki Tsuda et al. TOXICOLOGIC PATHOLOGY
- Chromosomes in Leukemia and Beyond: From Irrelevant to Central Players
- (2009) Janet D. Rowley Annual Review of Genomics and Human Genetics
- New cytochrome P450 mechanisms: implications for understanding molecular basis for drug toxicity at the level of the cytochrome
- (2009) Narasimhulu Shakunthala Expert Opinion on Drug Metabolism & Toxicology
- Assessment of in vivo genotoxicity of the rodent carcinogen furan: evaluation of DNA damage and induction of micronuclei in mouse splenocytes
- (2009) P. Leopardi et al. MUTAGENESIS
- Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach
- (2009) Lya G. Hernández et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Using chemical categories to fill data gaps in hazard assessment
- (2009) K. van Leeuwen et al. SAR AND QSAR IN ENVIRONMENTAL RESEARCH
- Current and Future Application of Genetic Toxicity Assays: The Role and Value of In Vitro Mammalian Assays
- (2009) Rosalie K. Elespuru et al. TOXICOLOGICAL SCIENCES
- Toxicity Testing in the 21st Century: A View from the Pharmaceutical Industry
- (2009) James S. MacDonald et al. TOXICOLOGICAL SCIENCES
- Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia
- (2008) Jordi Alcaraz et al. EMBO JOURNAL
- Predictivity of QSAR
- (2008) Romualdo Benigni et al. Journal of Chemical Information and Modeling
- Recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests: A follow-up to an ECVAM workshop
- (2008) David Kirkland et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens
- (2008) David Kirkland et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- Structure alerts for carcinogenicity, and the Salmonella assay system: A novel insight through the chemical relational databases technology
- (2008) R BENIGNI et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Network pharmacology: the next paradigm in drug discovery
- (2008) Andrew L Hopkins Nature Chemical Biology
- The tumor microenvironment and its role in promoting tumor growth
- (2008) T L Whiteside ONCOGENE
- Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment
- (2008) Robert J. Kavlock et al. RISK ANALYSIS
- More Toxin Tests Needed
- (2008) J. Huff SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started