Bis(monoacylglycerol)phosphate as a non-invasive biomarker to monitor the onset and time-course of phospholipidosis with drug-induced toxicities

1-O-Hexadecyl-2-O-methyl-3-O-(2'-acetamido-2'-deoxy-∃-D-glucopyranosyl)-sn-glycerol (Gln) induces cell death with more autophagosomes which is autophagy-independent

(2014) Luca Jahreiss et al.   Autophagy

Hepatic storage of bis(monoacylglycerol) phosphate without concomitant storage of sphingomyelin in a 72-year-old patient with a partial deficiency of sphingomyelinase

(2010) A. Poulos et al.   CLINICAL GENETICS

The LDL Receptor

(2009) Joseph L. Goldstein et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Intracellular sequestration of amiodarone: role of vacuolar ATPase and macroautophagic transition of the resulting vacuolar cytopathology

(2009) G Morissette et al.   BRITISH JOURNAL OF PHARMACOLOGY

Roles and regulation of secretory and lysosomal acid sphingomyelinase

(2009) Russell W. Jenkins et al.   CELLULAR SIGNALLING

Tissue-specific, non-invasive toxicity biomarkers: translation from preclinical safety assessment to clinical safety monitoring

(2009) Patrick Y Muller et al.   Expert Opinion on Drug Metabolism & Toxicology

A Strategy for Risk Management of Drug-Induced Phospholipidosis

(2009) Linda A. Chatman et al.   TOXICOLOGIC PATHOLOGY

Drug-induced phospholipidosis is caused by blockade of mannose 6-phosphate receptor-mediated targeting of lysosomal enzymes

(2008) Kazuhiko Ikeda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of Sterol Transport between Membranes and NPC2†

(2008) Zhi Xu et al.   BIOCHEMISTRY

Diverse antidepressants increase CDP-diacylglycerol production and phosphatidylinositide resynthesis in depression-relevant regions of the rat brain

(2008) Kimberly R Tyeryar et al.   BMC NEUROSCIENCE

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Extracellular Alix regulates integrin-mediated cell adhesions and extracellular matrix assembly

(2008) Shujuan Pan et al.   EMBO JOURNAL

Lysobisphosphatidic Acid Controls Endosomal Cholesterol Levels

(2008) Julien Chevallier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Early detection of acute kidney injury: Emerging new biomarkers (Review Article)

(2008) ZOLTAN H ENDRE et al.   NEPHROLOGY

Proteomic analysis of phospholipidosis in citalopram treated U937 cells – Support for the cholesterol biosynthesis hypothesis

(2008) Thomas H. Hutchinson et al.   TOXICOLOGY IN VITRO

Drug-induced Phospholipidosis -Pathological Aspects and Its Prediction

(2008) Takashi Nonoyama et al.   Journal of Toxicologic Pathology