Recent advances using zebrafish animal models for muscle disease drug discovery

Dysferlin and Animal Models for Dysferlinopathy

(2015) Kinji Kobayashi et al.   Journal of Toxicologic Pathology

Novel excitation-contraction coupling related genes reveal aspects of muscle weakness beyond atrophy—new hopes for treatment of musculoskeletal diseases

(2014) Heather Manring et al.   Frontiers in Physiology

What Can We Learn From Clinical Trials of Exon Skipping for DMD?

(2014) Qi-long Lu et al.   Molecular Therapy-Nucleic Acids

The myopathy-causing mutation DNM2-S619L leads to defective tubulation in vitro and in developing zebrafish

(2013) E. M. Gibbs et al.   Disease Models & Mechanisms

Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice

(2013) Chiara Mozzetta et al.   EMBO Molecular Medicine

Muscle dysfunction and structural defects of dystrophin-null sapje mutant zebrafish larvae are rescued by ataluren treatment

(2013) Mei Li et al.   FASEB JOURNAL

Swimming into prominence: the zebrafish as a valuable tool for studying human myopathies and muscular dystrophies

(2013) Elizabeth M. Gibbs et al.   FEBS Journal

A myogenic precursor cell that could contribute to regeneration in zebrafish and its similarity to the satellite cell

(2013) Ashley L. Siegel et al.   FEBS Journal

Lying low but ready for action: the quiescent muscle satellite cell

(2013) Didier Montarras et al.   FEBS Journal

Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling

(2013) Genri Kawahara et al.   HUMAN MOLECULAR GENETICS

Genetically modified pigs to model human diseases

(2013) Tatiana Flisikowska et al.   JOURNAL OF APPLIED GENETICS

Cellular and molecular mechanisms underlying muscular dystrophy

(2013) Fedik Rahimov et al.   JOURNAL OF CELL BIOLOGY

Neuromuscular junction abnormalities in DNM2-related centronuclear myopathy

(2013) Elizabeth M. Gibbs et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Control of muscle fibre-type diversity during embryonic development: The zebrafish paradigm

(2013) Harriet E. Jackson et al.   MECHANISMS OF DEVELOPMENT

Macrophage Plasticity and the Role of Inflammation in Skeletal Muscle Repair

(2013) Yacine Kharraz et al.   MEDIATORS OF INFLAMMATION

The 2014 version of the gene table of monogenic neuromuscular disorders (nuclear genome)

(2013) Jean-Claude Kaplan et al.   NEUROMUSCULAR DISORDERS

Genotype-phenotype correlations in recessive RYR1-related myopathies

(2013) Kimberly Amburgey et al.   Orphanet Journal of Rare Diseases

The Spinning Task: A New Protocol to Easily Assess Motor Coordination and Resistance in Zebrafish

(2013) Ana R. Blazina et al.   Zebrafish

The CRISPR System—Keeping Zebrafish Gene Targeting Fresh

(2013) Patrick R. Blackburn et al.   Zebrafish

Laminin-211 in skeletal muscle function

(2013) Johan Holmberg et al.   Cell Adhesion & Migration

A Lack of Premature Termination Codon Read-Through Efficacy of PTC124 (Ataluren) in a Diverse Array of Reporter Assays

(2013) Stuart P. McElroy et al.   PLOS BIOLOGY

Ataluren as an Agent for Therapeutic Nonsense Suppression

(2012) Stuart W. Peltz et al.   Annual Review of Medicine

Quantification of birefringence readily measures the level of muscle damage in zebrafish

(2012) Joachim Berger et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxidative stress and successful antioxidant treatment in models of RYR1-related myopathy

(2012) James J. Dowling et al.   BRAIN

Splice Modulating Therapies for Human Disease

(2012) Pietro Spitali et al.   CELL

Congenital Myopathies: An Update

(2012) Jessica R. Nance et al.   Current Neurology and Neuroscience Reports

Pharmacological therapies for muscular dystrophies

(2012) Hoda Abdel-Hamid et al.   CURRENT OPINION IN NEUROLOGY

Genetic elevation of Sphingosine 1-phosphate suppresses dystrophic muscle phenotypes in Drosophila

(2012) M. Pantoja et al.   DEVELOPMENT

In Vivo Imaging of Molecular Interactions at Damaged Sarcolemma

(2012) Urmas Roostalu et al.   DEVELOPMENTAL CELL

A model 450 million years in the making: zebrafish and vertebrate immunity

(2012) S. A. Renshaw et al.   Disease Models & Mechanisms

Zebrafish models flex their muscles to shed light on muscular dystrophies

(2012) J. Berger et al.   Disease Models & Mechanisms

Mutation spectrum in the large GTPase dynamin 2, and genotype-phenotype correlation in autosomal dominant centronuclear myopathy

(2012) Johann Böhm et al.   HUMAN MUTATION

Hooked! Modeling human disease in zebrafish

(2012) Cristina Santoriello et al.   JOURNAL OF CLINICAL INVESTIGATION

Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies

(2012) Joe N. Kornegay et al.   MAMMALIAN GENOME

Gene and cell-mediated therapies for muscular dystrophy

(2012) Patryk Konieczny et al.   MUSCLE & NERVE

Muscle diseases in the zebrafish

(2012) Yung-Yao Lin   NEUROMUSCULAR DISORDERS

NAD+ Biosynthesis Ameliorates a Zebrafish Model of Muscular Dystrophy

(2012) Michelle F. Goody et al.   PLOS BIOLOGY

Analysis of Pax7 expressing myogenic cells in zebrafish muscle development, injury, and models of disease

(2011) Claudia Seger et al.   DEVELOPMENTAL DYNAMICS

Progress in therapy for Duchenne muscular dystrophy

(2011) Rebecca J. Fairclough et al.   EXPERIMENTAL PHYSIOLOGY

The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies

(2011) Vandana Gupta et al.   HUMAN MOLECULAR GENETICS

Evaluation of exon-skipping strategies for Duchenne muscular dystrophy utilizing dystrophin-deficient zebrafish

(2011) Joachim Berger et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

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(2011) Silvia Consalvi et al.   MOLECULAR MEDICINE

Current Status of Pharmaceutical and Genetic Therapeutic Approaches to Treat DMD

(2011) Christophe Pichavant et al.   MOLECULAR THERAPY

DHODH modulates transcriptional elongation in the neural crest and melanoma

(2011) Richard Mark White et al.   NATURE

Embryonic Senescence and Laminopathies in a Progeroid Zebrafish Model

(2011) Eriko Koshimizu et al.   PLoS One

Drug screening in a zebrafish model of Duchenne muscular dystrophy

(2011) G. Kawahara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flightless flies: Drosophila models of neuromuscular disease

(2010) Thomas E. Lloyd et al.   Annals of the New York Academy of Sciences

Nrk2b-mediated NAD+ production regulates cell adhesion and is required for muscle morphogenesis in vivo

(2010) Michelle F. Goody et al.   DEVELOPMENTAL BIOLOGY

Zebrafish models of collagen VI-related myopathies

(2010) W.R. Telfer et al.   HUMAN MOLECULAR GENETICS

Dystrophin-deficient zebrafish feature aspects of the Duchenne muscular dystrophy pathology

(2010) Joachim Berger et al.   NEUROMUSCULAR DISORDERS

Centronuclear myopathies: A widening concept

(2010) Norma Beatriz Romero   NEUROMUSCULAR DISORDERS

ZFIN: enhancements and updates to the zebrafish model organism database

(2010) Y. Bradford et al.   NUCLEIC ACIDS RESEARCH

Non-Ca2+-conducting Ca2+ channels in fish skeletal muscle excitation-contraction coupling

(2010) J. Schredelseker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124

(2010) D. S. Auld et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sildenafil reverses cardiac dysfunction in the mdx mouse model of Duchenne muscular dystrophy

(2010) C. M. Adamo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct and dynamic myogenic populations in the vertebrate embryo

(2009) Margaret Buckingham et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Theoretic applicability of antisense-mediated exon skipping for Duchenne muscular dystrophy mutations

(2009) Annemieke Aartsma-Rus et al.   HUMAN MUTATION

Loss of Myotubularin Function Results in T-Tubule Disorganization in Zebrafish and Human Myotubular Myopathy

(2009) James J. Dowling et al.   PLoS Genetics

Mechanisms of Muscle Degeneration, Regeneration, and Repair in the Muscular Dystrophies

(2008) Gregory Q. Wallace et al.   Annual Review of Physiology

Time-Lapse Analysis and Mathematical Characterization Elucidate Novel Mechanisms Underlying Muscle Morphogenesis

(2008) Chelsi J. Snow et al.   PLoS Genetics