Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies

Systemic Delivery of Allogenic Muscle Stem Cells Induces Long-Term Muscle Repair and Clinical Efficacy in Duchenne Muscular Dystrophy Dogs

(2011) Karl Rouger et al.   AMERICAN JOURNAL OF PATHOLOGY

Longitudinal ambulatory measurements of gait abnormality in dystrophin-deficient dogs

(2011) Inès Barthélémy et al.   BMC MUSCULOSKELETAL DISORDERS

Preclinical Studies with Umbilical Cord Mesenchymal Stromal Cells in Different Animal Models for Muscular Dystrophy

(2011) Eder Zucconi et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study

(2011) Sebahattin Cirak et al.   LANCET

Regulation of the calpain and ubiquitin-proteasome systems in a canine model of muscular dystrophy

(2011) Kristine M. Wadosky et al.   MUSCLE & NERVE

Age-matched comparison reveals early electrocardiography and echocardiography changes in dystrophin-deficient dogs

(2011) Deborah M. Fine et al.   NEUROMUSCULAR DISORDERS

Muscular Dystrophy in Dogs

(2011) L. G. Miyazato et al.   VETERINARY PATHOLOGY

Leupeptin-based inhibitors do not improve the mdx phenotype

(2010) Joshua Selsby et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Sporadic occurrence of Duchenne Muscular Dystrophy: evidence for new mutation

(2010) C. Thomas Caskey et al.   CLINICAL GENETICS

Chronic administration of membrane sealant prevents severe cardiac injury and ventricular dilatation in dystrophic dogs

(2010) DeWayne Townsend et al.   JOURNAL OF CLINICAL INVESTIGATION

An intronic LINE-1 element insertion in the dystrophin gene aborts dystrophin expression and results in Duchenne-like muscular dystrophy in the corgi breed

(2010) Bruce F Smith et al.   LABORATORY INVESTIGATION

Expression of Dog Microdystrophin in Mouse and Dog Muscles by Gene Therapy

(2010) Christophe Pichavant et al.   MOLECULAR THERAPY

Widespread Muscle Expression of an AAV9 Human Mini-dystrophin Vector After Intravenous Injection in Neonatal Dystrophin-deficient Dogs

(2010) Joe N Kornegay et al.   MOLECULAR THERAPY

Eccentric contractions induce rapid isometric torque drop in dystrophin-deficient dogs

(2010) Christopher J. Tegeler et al.   MUSCLE & NERVE

Dystrophin Immunity in Duchenne's Muscular Dystrophy

(2010) Jerry R. Mendell et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Duchenne Muscular Dystrophy Gene Hot Spot Mutation in Dystrophin-Deficient Cavalier King Charles Spaniels Is Amenable to Exon 51 Skipping

(2010) Gemma L. Walmsley et al.   PLoS One

Efficacy of systemic morpholino exon-skipping in duchenne dystrophy dogs

(2009) Toshifumi Yokota et al.   ANNALS OF NEUROLOGY

Identification of three distinguishable phenotypes in golden retriever muscular dystrophy

(2009) C.E. Ambrosio et al.   GENETICS AND MOLECULAR RESEARCH

Hydrodynamic Limb Vein Injection of Adeno-Associated Virus Serotype 8 Vector Carrying Canine Myostatin Propeptide Gene into Normal Dogs Enhances Muscle Growth

(2009) Chunping Qiao et al.   HUMAN GENE THERAPY

Mutational spectrum of DMD mutations in dystrophinopathy patients: application of modern diagnostic techniques to a large cohort

(2009) Kevin M. Flanigan et al.   HUMAN MUTATION

Immune Responses to AAV in Canine Muscle Monitored by Cellular Assays and Noninvasive Imaging

(2009) Zejing Wang et al.   MOLECULAR THERAPY

Evaluation of dystrophic dog pathology by fat-suppressed T2-weighted imaging

(2009) Masanori Kobayashi et al.   MUSCLE & NERVE

The 6-minute walk test as a new outcome measure in Duchenne muscular dystrophy

(2009) Craig M. McDonald et al.   MUSCLE & NERVE

Gait analysis using accelerometry in dystrophin-deficient dogs

(2009) Inès Barthélémy et al.   NEUROMUSCULAR DISORDERS

Kinematics of gait in Golden Retriever Muscular Dystrophy

(2009) Anthony P. Marsh et al.   NEUROMUSCULAR DISORDERS

Characteristics and outcomes of cardiomyopathy in children with Duchenne or Becker muscular dystrophy: A comparative study from the Pediatric Cardiomyopathy Registry

(2008) David M. Connuck et al.   AMERICAN HEART JOURNAL

Systemic humanminidystrophingene transfer improves functions and life span of dystrophin and dystrophin/utrophin-deficient mice

(2008) Bing Wang et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Early transplantation of human immature dental pulp stem cells from baby teeth to golden retriever muscular dystrophy (GRMD) dogs: Local or systemic?

(2008) Irina Kerkis et al.   Journal of Translational Medicine

Hematopoietic Cell Transplantation Provides an Immune-tolerant Platform for Myoblast Transplantation in Dystrophic Dogs

(2008) Maura H Parker et al.   MOLECULAR THERAPY

A Single Intravenous Injection of Adeno-associated Virus Serotype-9 Leads to Whole Body Skeletal Muscle Transduction in Dogs

(2008) Yongping Yue et al.   MOLECULAR THERAPY

Transduction Efficiency and Immune Response Associated With the Administration of AAV8 Vector Into Dog Skeletal Muscle

(2008) Sachiko Ohshima et al.   MOLECULAR THERAPY

Ringo, a Golden Retriever Muscular Dystrophy (GRMD) dog with absent dystrophin but normal strength

(2008) C.E. Ambrósio et al.   NEUROMUSCULAR DISORDERS

Life expectancy and death from cardiomyopathy amongst carriers of Duchenne and Becker muscular dystrophy in Scotland

(2007) S M Holloway et al.   HEART

Gene expression profiling of normal and ruptured canine anterior cruciate ligaments

(2007) D.N. Clements et al.   OSTEOARTHRITIS AND CARTILAGE