标题
Novel approaches for the design and discovery of quorum-sensing inhibitors
作者
关键词
-
出版物
Expert Opinion on Drug Discovery
Volume 9, Issue 4, Pages 353-366
出版商
Informa Healthcare
发表日期
2014-03-05
DOI
10.1517/17460441.2014.894974
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Overcoming the Unexpected Functional Inversion of a PqsR Antagonist inPseudomonas aeruginosa: An In Vivo Potent Antivirulence Agent TargetingpqsQuorum Sensing
- (2013) Cenbin Lu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The Apparent Quorum-Sensing Inhibitory Activity of Pyrogallol Is a Side Effect of Peroxide Production
- (2013) Tom Defoirdt et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Identification of Five Structurally Unrelated Quorum-Sensing Inhibitors of Pseudomonas aeruginosa from a Natural-Derivative Database
- (2013) Sean Yang-Yi Tan et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Efficacy of AiiM, anN-Acylhomoserine Lactonase, against Pseudomonas aeruginosa in a Mouse Model of Acute Pneumonia
- (2013) Yohei Migiyama et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- High-Sensitivity Monoclonal Antibodies Specific for Homoserine Lactones Protect Mice from Lethal Pseudomonas aeruginosa Infections
- (2013) Soumya Palliyil et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Sol–gel silica controlled release thin films for the inhibition of methicillin-resistant Staphylococcus aureus
- (2013) Sanjib Bhattacharyya et al. BIOMATERIALS
- In silico and experimental methods revealed highly diverse bacteria with quorum sensing and aromatics biodegradation systems – A potential broad application on bioremediation
- (2013) Yili Huang et al. BIORESOURCE TECHNOLOGY
- High-Throughput Screening of Inhibitors TargetingAgr/FsrQuorum Sensing inStaphylococcus aureusandEnterococcus faecalis
- (2013) Said E. DESOUKY et al. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- Rule–based regulatory and metabolic model for Quorum sensing in P. aeruginosa
- (2013) Nadine S Schaadt et al. BMC Systems Biology
- Dynamics of the quorum sensing switch: stochastic and non-stationary effects
- (2013) Marc Weber et al. BMC Systems Biology
- Biologically inspired strategies for combating bacterial biofilms
- (2013) Meghan S Blackledge et al. CURRENT OPINION IN PHARMACOLOGY
- Quo vadis quorum quenching?
- (2013) Jie Zhu et al. CURRENT OPINION IN PHARMACOLOGY
- Quorum sensing inhibitors: a patent review
- (2013) Tianyu Jiang et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Characterization ofsilin Invasive Group A and G Streptococci: Antibodies against Bacterial Pheromone Peptide SilCR Result in Severe Infection
- (2013) Ayelet Michael-Gayego et al. INFECTION AND IMMUNITY
- Quorum Quenching Enzymes and Their Application in Degrading Signal Molecules to Block Quorum Sensing-Dependent Infection
- (2013) Fang Chen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Negative regulation of bacterial quorum sensing tunes public goods cooperation
- (2013) Rashmi Gupta et al. ISME Journal
- Design, Synthesis, and Evaluation of Fimbrolide–Nitric Oxide Donor Hybrids as Antimicrobial Agents
- (2013) Samuel K. Kutty et al. JOURNAL OF MEDICINAL CHEMISTRY
- Combining in Silico and Biophysical Methods for the Development of Pseudomonas aeruginosa Quorum Sensing Inhibitors: An Alternative Approach for Structure-Based Drug Design
- (2013) J. Henning Sahner et al. JOURNAL OF MEDICINAL CHEMISTRY
- Attenuating Staphylococcus aureus Virulence Gene Regulation: A Medicinal Chemistry Perspective
- (2013) Christopher P. Gordon et al. JOURNAL OF MEDICINAL CHEMISTRY
- Candida albicans and Pseudomonas aeruginosa interactions: More than an opportunistic criminal association?
- (2013) J.-B. Méar et al. MEDECINE ET MALADIES INFECTIEUSES
- Exploiting Quorum Sensing To Confuse Bacterial Pathogens
- (2013) B. LaSarre et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- A semi-quantitative model of Quorum-Sensing in Staphylococcus aureus, approved by microarray meta-analyses and tested by mutation studies
- (2013) Christof Audretsch et al. Molecular BioSystems
- Role of PON2 in innate immune response in an acute infection model
- (2013) Asokan Devarajan et al. MOLECULAR GENETICS AND METABOLISM
- Systematic Mutational Analysis of the Putative Hydrolase PqsE: Toward a Deeper Molecular Understanding of Virulence Acquisition in Pseudomonas aeruginosa
- (2013) Benjamin Folch et al. PLoS One
- QsIA disrupts LasR dimerization in antiactivation of bacterial quorum sensing
- (2013) H. Fan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A high-throughput screen for quorum-sensing inhibitors that target acyl-homoserine lactone synthases
- (2013) Quin H. Christensen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 3D printing of microscopic bacterial communities
- (2013) J. L. Connell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Plant-Derived Natural Products as Sources of Anti-Quorum Sensing Compounds
- (2013) Chong-Lek Koh et al. SENSORS
- Quorum sensing inhibitors: how strong is the evidence?
- (2013) Tom Defoirdt et al. TRENDS IN MICROBIOLOGY
- The use of quorum sensing to improve vaccine immune response
- (2013) R.T. Sturbelle et al. VACCINE
- A Quorum-Sensing-Induced Bacteriophage Defense Mechanism
- (2013) N. M. Hoyland-Kroghsbo et al. mBio
- Novel Quorum-Sensing Peptides Mediating Interspecies Bacterial Cell Death
- (2013) S. Kumar et al. mBio
- Nox2 Modification of LDL Is Essential for Optimal Apolipoprotein B-mediated Control of agr Type III Staphylococcus aureus Quorum-sensing
- (2013) Pamela R. Hall et al. PLoS Pathogens
- Structural Basis for Native Agonist and Synthetic Inhibitor Recognition by the Pseudomonas aeruginosa Quorum Sensing Regulator PqsR (MvfR)
- (2013) Aravindan Ilangovan et al. PLoS Pathogens
- Resistance to the quorum-quenching compounds brominated furanone C-30 and 5-fluorouracil inPseudomonas aeruginosaclinical isolates
- (2013) Rodolfo García-Contreras et al. Pathogens and Disease
- Ajoene, a Sulfur-Rich Molecule from Garlic, Inhibits Genes Controlled by Quorum Sensing
- (2012) Tim Holm Jakobsen et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Evolution of Resistance to Quorum Quenching in Digital Organisms
- (2012) Benjamin E. Beckmann et al. ARTIFICIAL LIFE
- Bacterial cooperation in the wild and in the clinic: Are pathogen social behaviours relevant outside the laboratory?
- (2012) Freya Harrison BIOESSAYS
- Inhibition of quorum sensing in a computational biofilm simulation
- (2012) J.A. Fozard et al. BIOSYSTEMS
- Quorum sensing inhibitors: An overview
- (2012) Vipin Chandra Kalia BIOTECHNOLOGY ADVANCES
- Encapsulated fusion protein confers “sense and respond” activity to chitosan-alginate capsules to manipulate bacterial quorum sensing
- (2012) Apoorv Gupta et al. BIOTECHNOLOGY AND BIOENGINEERING
- Eugenol inhibits quorum sensing at sub-inhibitory concentrations
- (2012) Liman Zhou et al. BIOTECHNOLOGY LETTERS
- Bioinspired, releasable quorum sensing modulators
- (2012) José Gomes et al. CHEMICAL COMMUNICATIONS
- Discovery of Antagonists of PqsR, a Key Player in 2-Alkyl-4-quinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa
- (2012) Cenbin Lu et al. CHEMISTRY & BIOLOGY
- Identification of LasR Ligands through a Virtual Screening Approach
- (2012) Søren Skovstrup et al. ChemMedChem
- Development of a dry, stable and inhalable acyl–homoserine–lactone–acylase powder formulation for the treatment of pulmonary Pseudomonas aeruginosa infections
- (2012) Mariana Wahjudi et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- C4-Alkoxy-HPD: A Potent Class of Synthetic Modulators Surpassing Nature in AI-2 Quorum Sensing
- (2012) Kyoji Tsuchikama et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Chemical methods to interrogate bacterial quorum sensing pathways
- (2012) Thanit Praneenararat et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Antisense RNA that affectsRhodopseudomonas palustrisquorum-sensing signal receptor expression
- (2012) Hidetada Hirakawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A new route towards fimbrolide analogues: importance of the exomethylene motif in LuxR dependent quorum sensing inhibition
- (2012) Mohamad Sabbah et al. MedChemComm
- Paraoxonases as Potential Antibiofilm Agents: Their Relationship with Quorum-Sensing Signals in Gram-Negative Bacteria
- (2011) Jordi Camps et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Quenching the quorum sensing system: potential antibacterial drug targets
- (2011) Vipin Chandra Kalia et al. CRITICAL REVIEWS IN MICROBIOLOGY
- Quorum quenching quandary: resistance to antivirulence compounds
- (2011) Toshinari Maeda et al. ISME Journal
- Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody
- (2011) Robert N. Kirchdoerfer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of Virulence Gene Expression in Staphylococcus aureus by Novel Depsipeptides from a Marine Photobacterium
- (2011) Maria Mansson et al. Marine Drugs
- Anti-activator QslA defines the quorum sensing threshold and response in Pseudomonas aeruginosa
- (2011) Qihui Seet et al. MOLECULAR MICROBIOLOGY
- A Novel Metagenomic Short-Chain Dehydrogenase/Reductase Attenuates Pseudomonas aeruginosa Biofilm Formation and Virulence on Caenorhabditis elegans
- (2011) Patrick Bijtenhoorn et al. PLoS One
- Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase
- (2011) J. Chung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Biological Nanofactories Target and Activate Epithelial Cell Surfaces for Modulating Bacterial Quorum Sensing and Interspecies Signaling
- (2010) Colin G. Hebert et al. ACS Nano
- Challenges of antibacterial discovery revisited
- (2010) Michael N. Gwynn et al. Annals of the New York Academy of Sciences
- Macromolecular Inhibition of Quorum Sensing: Enzymes, Antibodies, and Beyond
- (2010) Neri Amara et al. CHEMICAL REVIEWS
- How to discover new antibiotics: harvesting the parvome
- (2010) Julian Davies CURRENT OPINION IN CHEMICAL BIOLOGY
- Identification of mutants with altered phenazine production in Pseudomonas aeruginosa
- (2010) H. Liang et al. JOURNAL OF MEDICAL MICROBIOLOGY
- Design and Synthesis of Potent “Sulfur-Free” Transition State Analogue Inhibitors of 5′-Methylthioadenosine Nucleosidase and 5′-Methylthioadenosine Phosphorylase
- (2010) Alistair I. Longshaw et al. JOURNAL OF MEDICINAL CHEMISTRY
- Microbial communication and virulence: lessons from evolutionary theory
- (2010) S. P. Diggle MICROBIOLOGY-SGM
- A unique regulator controls the activation threshold of quorum-regulated genes inPseudomonas aeruginosa
- (2010) Richard Siehnel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Quorum Sensing Inhibition Selects for Virulence and Cooperation in Pseudomonas aeruginosa
- (2010) Thilo Köhler et al. PLoS Pathogens
- Modeling Growth and Quorum Sensing in Biofilms Grown in Microfluidic Chambers
- (2009) Vijay Janakiraman et al. ANNALS OF BIOMEDICAL ENGINEERING
- Quorum-Quenching Acylase Reduces the Virulence of Pseudomonas aeruginosa in a Caenorhabditis elegans Infection Model
- (2009) E. Papaioannou et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Quorum Sensing and the Social Evolution of Bacterial Virulence
- (2009) Kendra P. Rumbaugh et al. CURRENT BIOLOGY
- Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules
- (2009) Paul Williams et al. CURRENT OPINION IN MICROBIOLOGY
- Quorum sensing inhibitors: a patent overview
- (2009) Jiachuan Pan et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Transition state analogs of 5′-methylthioadenosine nucleosidase disrupt quorum sensing
- (2009) Jemy A Gutierrez et al. Nature Chemical Biology
- Cooperation and virulence of clinical Pseudomonas aeruginosa populations
- (2009) T. Kohler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effects of Antibiotics on Quorum Sensing in Pseudomonas aeruginosa
- (2008) M. E. Skindersoe et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Bacterial quorum sensing: a new target for anti-infective immunotherapy
- (2008) Gunnar F Kaufmann et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- The quorum quenching antibody RS2-1G9 protects macrophages from the cytotoxic effects of the Pseudomonas aeruginosa quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone
- (2008) Gunnar F. Kaufmann et al. MOLECULAR IMMUNOLOGY
- Discovery of a Quorum-Sensing Inhibitor of Drug-Resistant Staphylococcal Infections by Structure-Based Virtual Screening
- (2008) M. D. Kiran et al. MOLECULAR PHARMACOLOGY
- The Communication Factor EDF and the Toxin–Antitoxin Module mazEF Determine the Mode of Action of Antibiotics
- (2008) Ilana Kolodkin-Gal et al. PLOS BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started