Candidiasis drug discovery and development: new approaches targeting virulence for discovering and identifying new drugs

A simple and reproducible 96-well plate-based method for the formation of fungal biofilms and its application to antifungal susceptibility testing

(2014) Christopher G Pierce et al.   Nature Protocols

A Recently Evolved Transcriptional Network Controls Biofilm Development in Candida albicans

(2012) Clarissa J. Nobile et al.   CELL

Interplay between Candida albicans and the Mammalian Innate Host Defense

(2012) Shih-Chin Cheng et al.   INFECTION AND IMMUNITY

Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options

(2012) J. C. O. Sardi et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Retigeric Acid B Attenuates the Virulence of Candida albicans via Inhibiting Adenylyl Cyclase Activity Targeted by Enhanced Farnesol Production

(2012) Wenqiang Chang et al.   PLoS One

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Novel high-throughput screen against Candida albicans identifies antifungal potentiators and agents effective against biofilms

(2011) M. D. LaFleur et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Effect of exogenous administration of Candida albicans autoregulatory alcohols in a murine model of hematogenously disseminated candidiasis

(2011) Margarida Martins et al.   JOURNAL OF BASIC MICROBIOLOGY

Addition of DNase improves the in vitro activity of antifungal drugs against Candida albicans biofilms

(2011) Margarida Martins et al.   MYCOSES

Growth of Candida albicans hyphae

(2011) Peter E. Sudbery   NATURE REVIEWS MICROBIOLOGY

Validation of the Tetracycline Regulatable Gene Expression System for the Study of the Pathogenesis of Infectious Disease

(2011) Ashok K. Chaturvedi et al.   PLoS One

Development of a High-Throughput Candida albicans Biofilm Chip

(2011) Anand Srinivasan et al.   PLoS One

Small Molecule Inhibitors of the Candida albicans Budded-to-Hyphal Transition Act through Multiple Signaling Pathways

(2011) John Midkiff et al.   PLoS One

Bisbibenzyls, a New Type of Antifungal Agent, Inhibit Morphogenesis Switch and Biofilm Formation through Upregulation of DPP3 in Candida albicans

(2011) Li Zhang et al.   PLoS One

Hsp90 Governs Dispersion and Drug Resistance of Fungal Biofilms

(2011) Nicole Robbins et al.   PLoS Pathogens

A Biphasic Innate Immune MAPK Response Discriminates between the Yeast and Hyphal Forms of Candida albicans in Epithelial Cells

(2010) David L. Moyes et al.   Cell Host & Microbe

Candidosis, a new challenge

(2010) Rubén López-Martínez   CLINICS IN DERMATOLOGY

An insight into the antifungal pipeline: selected new molecules and beyond

(2010) Luis Ostrosky-Zeichner et al.   NATURE REVIEWS DRUG DISCOVERY

Oropharyngeal candidiasis in the era of antiretroviral therapy

(2010) George R. Thompson et al.   ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS

Mutanobactin A from the human oral pathogen Streptococcus mutans is a cross-kingdom regulator of the yeast-mycelium transition

(2010) P. Matthew Joyner et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Capric Acid Secreted by S. boulardii Inhibits C. albicans Filamentous Growth, Adhesion and Biofilm Formation

(2010) Anna Murzyn et al.   PLoS One

Dispersion as an Important Step in the Candida albicans Biofilm Developmental Cycle

(2010) Priya Uppuluri et al.   PLoS Pathogens

Clinical Practice Guidelines for the Management of Candidiasis: 2009 Update by the Infectious Diseases Society of America

(2009) Peter G. Pappas et al.   CLINICAL INFECTIOUS DISEASES

Our Current Understanding of Fungal Biofilms

(2009) Gordon Ramage et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Targeting virulence: A new paradigm for antifungals

(2009) Katharina Gauwerky et al.   DRUG DISCOVERY TODAY

Presence of Extracellular DNA in the Candida albicans Biofilm Matrix and its Contribution to Biofilms

(2009) Margarida Martins et al.   MYCOPATHOLOGIA

Inhibition of Candida albicans biofilm formation on denture material

(2009) Spencer Redding et al.   ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS

Early-Expressed Chemokines Predict Kidney Immunopathology in Experimental Disseminated Candida albicans Infections

(2009) Donna M. MacCallum et al.   PLoS One

Pyrosequencing To Detect Mutations in FKS1 That Confer Reduced Echinocandin Susceptibility in Candida albicans

(2008) N. P. Wiederhold et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synergistic Effect of Calcineurin Inhibitors and Fluconazole against Candida albicans Biofilms

(2008) P. Uppuluri et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pseudomonas aeruginosa-Candida albicans Interactions: Localization and Fungal Toxicity of a Phenazine Derivative

(2008) J. Gibson et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

In vitro efficacies of caspofungin or micafungin catheter lock solutions on Candida albicans biofilm growth

(2008) E. Cateau et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

UME6, a Novel Filament-specific Regulator of Candida albicans Hyphal Extension and Virulence

(2008) Mohua Banerjee et al.   MOLECULAR BIOLOGY OF THE CELL

Expression levels of a filament-specific transcriptional regulator are sufficient to determine Candida albicans morphology and virulence

(2008) P. L. Carlisle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An integrated model of the recognition of Candida albicans by the innate immune system

(2007) Mihai G. Netea et al.   NATURE REVIEWS MICROBIOLOGY