Lessons from high-throughput protein crystallization screening: 10 years of practical experience
出版年份 2011 全文链接
标题
Lessons from high-throughput protein crystallization screening: 10 years of practical experience
作者
关键词
-
出版物
Expert Opinion on Drug Discovery
Volume 6, Issue 5, Pages 465-480
出版商
Informa Healthcare
发表日期
2011-03-22
DOI
10.1517/17460441.2011.566857
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Femtosecond X-ray protein nanocrystallography
- (2011) Henry N. Chapman et al. NATURE
- The minimum crystal size needed for a complete diffraction data set
- (2010) James M. Holton et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Challenges and opportunities for new protein crystallization strategies in structure-based drug design
- (2010) Jessica Lynn Grey et al. Expert Opinion on Drug Discovery
- New surface contacts formed upon reductive lysine methylation: Improving the probability of protein crystallization
- (2010) Pawel Sledz et al. PROTEIN SCIENCE
- Crystallization and preliminary X-ray studies of the N-domain of the Wilson disease associated protein
- (2009) Lili Liu et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- Structural Characterization of the Hemophore HasAp fromPseudomonas aeruginosa: NMR Spectroscopy Reveals Protein−Protein Interactions between Holo-HasAp and Hemoglobin†,‡
- (2009) Aileen Y. Alontaga et al. BIOCHEMISTRY
- Computational analysis of membrane proteins: the largest class of drug targets
- (2009) Yalini Arinaminpathy et al. DRUG DISCOVERY TODAY
- Dimeric Quaternary Structure of the Prototypical Dual Specificity Phosphatase VH1
- (2009) Adem C. Koksal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Toxoplasma gondiiCathepsin L Is the Primary Target of the Invasion-inhibitory Compound Morpholinurea-leucyl-homophenyl-vinyl Sulfone Phenyl
- (2009) Eric T. Larson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Three-Dimensional Pharmacophore Methods in Drug Discovery
- (2009) Andrew R. Leach et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Crystal Structure of the Pseudomonas dacunhae Aspartate-β-Decarboxylase Dodecamer Reveals an Unknown Oligomeric Assembly for a Pyridoxal-5′-Phosphate-Dependent Enzyme
- (2009) Santiago Lima et al. JOURNAL OF MOLECULAR BIOLOGY
- Different Poses for Ligand and Chaperone in Inhibitor-Bound Hsp90 and GRP94: Implications for Paralog-Specific Drug Design
- (2009) Robert M. Immormino et al. JOURNAL OF MOLECULAR BIOLOGY
- Active-Site Gating Regulates Substrate Selectivity in a Chymotrypsin-Like Serine Protease
- (2009) Troy A. Johnson et al. JOURNAL OF MOLECULAR BIOLOGY
- Inducer responses of BenM, a LysR-type transcriptional regulator fromAcinetobacter baylyiADP1
- (2009) Sarah H. Craven et al. MOLECULAR MICROBIOLOGY
- Molecular mimicry of SUMO promotes DNA repair
- (2009) John Prudden et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- ProteinCCD: enabling the design of protein truncation constructs for expression and crystallization experiments
- (2009) W. T. M. Mooij et al. NUCLEIC ACIDS RESEARCH
- Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance
- (2009) J. D. Ho et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal structure of dimeric cardiac L-type calcium channel regulatory domains bridged by Ca2+{middle dot}calmodulins
- (2009) J. L. Fallon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Determination and application of empirically derived detergent phase boundaries to effectively crystallize membrane proteins
- (2009) Mary Koszelak-Rosenblum et al. PROTEIN SCIENCE
- Insight into the substrate length restriction of M32 carboxypeptidases: Characterization of two distinct subfamilies
- (2009) Marianne M. Lee et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- The 2.1 Å crystal structure of an acyl-CoA synthetase fromMethanosarcina acetivoransreveals an alternate acyl-binding pocket for small branched acyl substrates
- (2009) Manish B. Shah et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- In situX-ray analysis of protein crystals in low-birefringent and X-ray transmissive plastic microchannels
- (2008) Joseph D. Ng et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Establishing a training set through the visual analysis of crystallization trials. Part II: crystal examples
- (2008) Edward H. Snell et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Establishing a training set through the visual analysis of crystallization trials. Part I: ∼150 000 images
- (2008) Edward H. Snell et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- The application and use of chemical space mapping to interpret crystallization screening results
- (2008) Edward H. Snell et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Structure of NS1A effector domain from the influenza A/Udorn/72 virus
- (2008) Shuangluo Xia et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Phoenito experiments: combining the strengths of commercial crystallization automation
- (2008) Janet Newman et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- Structure of aTrypanosoma bruceiα/β-hydrolase fold protein with unknown function
- (2008) Ethan A. Merritt et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- Crystal Structure of the Pyocyanin Biosynthetic Protein PhzS†‡
- (2008) Bryan T. Greenhagen et al. BIOCHEMISTRY
- Structural Characterization of a 140° Domain Movement in the Two-Step Reaction Catalyzed by 4-Chlorobenzoate:CoA Ligase†‡
- (2008) Albert S. Reger et al. BIOCHEMISTRY
- Hexameric ring structure of the N-terminal domain of Mycobacterium tuberculosis DnaB helicase
- (2008) Tapan Biswas et al. FEBS Journal
- AutoSherlock: a program for effective crystallization data analysis
- (2008) Raymond M. Nagel et al. JOURNAL OF APPLIED CRYSTALLOGRAPHY
- Crystal Structure and Autoactivation Pathway of the Precursor Form of Human Tripeptidyl-peptidase 1, the Enzyme Deficient in Late Infantile Ceroid Lipofuscinosis
- (2008) Jayita Guhaniyogi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal Structure of the MACPF Domain of Human Complement Protein C8α in Complex with the C8γ Subunit
- (2008) Daniel J. Slade et al. JOURNAL OF MOLECULAR BIOLOGY
- Structures of Substrate- and Inhibitor-Bound Adenosine Deaminase from a Human Malaria Parasite Show a Dramatic Conformational Change and Shed Light on Drug Selectivity
- (2008) Eric T. Larson et al. JOURNAL OF MOLECULAR BIOLOGY
- Three-dimensional Structures of Pseudomonas aeruginosa PvcA and PvcB, Two Proteins Involved in the Synthesis of 2-Isocyano-6,7-dihydroxycoumarin
- (2008) Eric J. Drake et al. JOURNAL OF MOLECULAR BIOLOGY
- The Capsid of the Small RNA Phage PRR1 Is Stabilized by Metal Ions
- (2008) Magnus Persson et al. JOURNAL OF MOLECULAR BIOLOGY
- Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies
- (2008) Tracy L. Arakaki et al. MOLECULAR MICROBIOLOGY
- Understanding the physical properties that control protein crystallization by analysis of large-scale experimental data
- (2008) W Nicholson Price II et al. NATURE BIOTECHNOLOGY
- Structure of the GspK–GspI–GspJ complex from the enterotoxigenic Escherichia coli type 2 secretion system
- (2008) Konstantin V Korotkov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started