Radiolabeled nanobodies as theranostic tools in targeted radionuclide therapy of cancer

Generation and characterization of nanobodies targeting PSMA for molecular imaging of prostate cancer

(2014) Mehdi Evazalipour et al.   Contrast Media & Molecular Imaging

Radium-223 Dichloride: A Review of Its Use in Patients with Castration-Resistant Prostate Cancer with Symptomatic Bone Metastases

(2014) Matt Shirley et al.   DRUGS

Molecular Imaging with Macrophage CRIg-Targeting Nanobodies for Early and Preclinical Diagnosis in a Mouse Model of Rheumatoid Arthritis

(2014) F. Zheng et al.   JOURNAL OF NUCLEAR MEDICINE

Improved Tumor Targeting of Anti-HER2 Nanobody Through N-Succinimidyl 4-Guanidinomethyl-3-Iodobenzoate Radiolabeling

(2014) M. Pruszynski et al.   JOURNAL OF NUCLEAR MEDICINE

Targeted Radionuclide Therapy with A 177Lu-labeled Anti-HER2 Nanobody

(2014) Matthias D'Huyvetter et al.   Theranostics

Albumin as a versatile platform for drug half-life extension

(2013) Darrell Sleep et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

In Vivo and In Vitro Studies on Renal Uptake of Radiolabeled Affibody Molecules for Imaging of HER2 Expression in Tumors

(2013) Mohamed Altai et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Pharmacokinetics and Imaging of 212Pb-TCMC-Trastuzumab After Intraperitoneal Administration in Ovarian Cancer Patients

(2013) Ruby F. Meredith et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Accurate assessment of long-term nephrotoxicity after peptide receptor radionuclide therapy with 177Lu-octreotate

(2013) Amir Sabet et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in neuroendocrine tumours

(2013) John J. Zaknun et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Camelid single-domain antibody-fragment engineering for (pre)clinicalin vivomolecular imaging applications: adjusting the bullet to its target

(2013) Jens De Vos et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

SPECT Imaging of Joint Inflammation with Nanobodies Targeting the Macrophage Mannose Receptor in a Mouse Model for Rheumatoid Arthritis

(2013) S. Put et al.   JOURNAL OF NUCLEAR MEDICINE

Synthesis, Preclinical Validation, Dosimetry, and Toxicity of 68Ga-NOTA-Anti-HER2 Nanobodies for iPET Imaging of HER2 Receptor Expression in Cancer

(2013) C. Xavier et al.   JOURNAL OF NUCLEAR MEDICINE

Imaging and radioimmunotherapy of multiple myeloma with anti-idiotypic Nanobodies

(2013) M Lemaire et al.   LEUKEMIA

Antibodies to watch in 2014

(2013) Janice M Reichert   mAbs

Trial Watch

(2013) Erika Vacchelli et al.   OncoImmunology

Improvement of Radioimmunotherapy Using Pretargeting

(2013) Eric Frampas et al.   Frontiers in Oncology

Influence of DOTA Chelator Position on Biodistribution and Targeting Properties of 111In-Labeled Synthetic Anti-HER2 Affibody Molecules

(2012) Anna Perols et al.   BIOCONJUGATE CHEMISTRY

Nanobody-Based Targeting of the Macrophage Mannose Receptor for EffectiveIn VivoImaging of Tumor-Associated Macrophages

(2012) Kiavash Movahedi et al.   CANCER RESEARCH

Nanobodies Targeting Mouse/Human VCAM1 for the Nuclear Imaging of Atherosclerotic Lesions

(2012) Alexis Broisat et al.   CIRCULATION RESEARCH

Development of177Lu-nanobodies for radioimmunotherapy of HER2-positive breast cancer: evaluation of different bifunctional chelators

(2012) Matthias D'Huyvetter et al.   Contrast Media & Molecular Imaging

Lutetium-labelled peptides for therapy of neuroendocrine tumours

(2012) B. L. R. Kam et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Nanobodies Targeting the Hepatocyte Growth Factor: Potential New Drugs for Molecular Cancer Therapy

(2012) M. J. W. D. Vosjan et al.   MOLECULAR CANCER THERAPEUTICS

Amplification of DNA damage by a γH2AX-targeted radiopharmaceutical

(2012) Bart Cornelissen et al.   NUCLEAR MEDICINE AND BIOLOGY

Targeting breast carcinoma with radioiodinated anti-HER2 Nanobody

(2012) Marek Pruszynski et al.   NUCLEAR MEDICINE AND BIOLOGY

Molecular Theranostics: A Primer for the Imaging Professional

(2011) Daniel Y. Lee et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Facile labelling of an anti-epidermal growth factor receptor Nanobody with 68Ga via a novel bifunctional desferal chelate for immuno-PET

(2011) Maria J. W. D. Vosjan et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Comparative evaluation of synthetic anti-HER2 Affibody molecules site-specifically labelled with 111In using N-terminal DOTA, NOTA and NODAGA chelators in mice bearing prostate cancer xenografts

(2011) Jennie Malmberg et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Preclinical screening of anti-HER2 nanobodies for molecular imaging of breast cancer

(2011) Ilse Vaneycken et al.   FASEB JOURNAL

A biparatopic anti-EGFR nanobody efficiently inhibits solid tumour growth

(2011) Rob C. Roovers et al.   INTERNATIONAL JOURNAL OF CANCER

Molecular Design and Optimization of 99mTc-Labeled Recombinant Affibody Molecules Improves Their Biodistribution and Imaging Properties

(2011) H. Wallberg et al.   JOURNAL OF NUCLEAR MEDICINE

Clinical radioimmunotherapy—the role of radiobiology

(2011) Jean-Pierre Pouget et al.   Nature Reviews Clinical Oncology

Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions

(2011) A. Mishra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted Radionuclide Therapy

(2011) Devrim Ersahin et al.   Cancers

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Efficient Tumor Targeting with High-Affinity Designed Ankyrin Repeat Proteins: Effects of Affinity and Molecular Size

(2010) C. Zahnd et al.   CANCER RESEARCH

Localization, mechanism and reduction of renal retention of technetium-99m labeled epidermal growth factor receptor-specific nanobody in mice

(2010) Lea Olive Tchouate Gainkam et al.   Contrast Media & Molecular Imaging

Preliminary evaluation of 177Lu-labeled knottin peptides for integrin receptor-targeted radionuclide therapy

(2010) Lei Jiang et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Nanobodies as Tools for In Vivo Imaging of Specific Immune Cell Types

(2010) K. De Groeve et al.   JOURNAL OF NUCLEAR MEDICINE

In Vitro Analysis and In Vivo Tumor Targeting of a Humanized, Grafted Nanobody in Mice Using Pinhole SPECT/Micro-CT

(2010) I. Vaneycken et al.   JOURNAL OF NUCLEAR MEDICINE

Radioimmunotherapy of Lymphoma: Bexxar and Zevalin

(2010) Stanley J. Goldsmith   SEMINARS IN NUCLEAR MEDICINE

Engineered affinity proteins for tumour-targeting applications

(2009) Mikaela Friedman et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Engineered Knottin Peptides: A New Class of Agents for Imaging Integrin Expression in Living Subjects

(2009) R. H. Kimura et al.   CANCER RESEARCH

Dose-response effect of Gelofusine on renal uptake and retention of radiolabelled octreotate in rats with CA20948 tumours

(2009) Marleen Melis et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

The Benefits and Risks of I-131 Therapy in Patients with Well-Differentiated Thyroid Cancer

(2009) Douglas Van Nostrand   THYROID

General Strategy to Humanize a Camelid Single-domain Antibody and Identification of a Universal Humanized Nanobody Scaffold

(2008) Cécile Vincke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparison of the Biodistribution and Tumor Targeting of Two 99mTc-Labeled Anti-EGFR Nanobodies in Mice, Using Pinhole SPECT/Micro-CT

(2008) L. O. T. Gainkam et al.   JOURNAL OF NUCLEAR MEDICINE

Improved tumor targeting of anti-epidermal growth factor receptor Nanobodies through albumin binding: taking advantage of modular Nanobody technology

(2008) B. M. Tijink et al.   MOLECULAR CANCER THERAPEUTICS

Protein therapeutics: a summary and pharmacological classification

(2007) Benjamin Leader et al.   NATURE REVIEWS DRUG DISCOVERY