Therapeutic and prophylactic DNA vaccines for HIV-1

Therapeutic Vaccination with Simian Immunodeficiency Virus (SIV)-DNA+IL-12 or IL-15 Induces Distinct CD8 Memory Subsets in SIV-Infected Macaques

(2014) R. Halwani et al.   JOURNAL OF IMMUNOLOGY

The future of human DNA vaccines

(2012) Lei Li et al.   JOURNAL OF BIOTECHNOLOGY

Comparing the effect of IL-12 genetic adjuvant and alum non-genetic adjuvant on the efficiency of the cocktail DNA vaccine containing plasmids encoding SAG-1 and ROP-2 of Toxoplasma gondii

(2012) Kamy Hosseinian Khosroshahi et al.   PARASITOLOGY RESEARCH

Safety and Immunogenicity of an HIV-1 Gag DNA Vaccine with or without IL-12 and/or IL-15 Plasmid Cytokine Adjuvant in Healthy, HIV-1 Uninfected Adults

(2012) Spyros A. Kalams et al.   PLoS One

Minimally invasive and surface electroporation delivery of DNA vaccines for the induction of robust humoral immune responses against HIV antigens

(2012) NY Sardesai et al.   Retrovirology

Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression

(2011) A. R. Hersperger et al.   BLOOD

DNA/NYVAC Vaccine Regimen Induces HIV-Specific CD4 and CD8 T-Cell Responses in Intestinal Mucosa

(2011) M. Perreau et al.   JOURNAL OF VIROLOGY

Broad and potent immune responses to a low dose intradermal HIV-1 DNA boosted with HIV-1 recombinant MVA among healthy adults in Tanzania

(2011) Muhammad Bakari et al.   VACCINE

Selected approaches for increasing HIV DNA vaccine immunogenicity in vivo

(2011) Natalie A Hutnick et al.   Current Opinion in Virology

Strong HIV-Specific CD4+ and CD8+ T-Lymphocyte Proliferative Responses in Healthy Individuals Immunized with an HIV-1 DNA Vaccine and Boosted with Recombinant Modified Vaccinia Virus Ankara Expressing HIV-1 Genes

(2010) S. Aboud et al.   Clinical and Vaccine Immunology

DNA vaccines for targeting bacterial infections

(2010) Mariana Ingolotti et al.   Expert Review of Vaccines

DNA vaccines: an historical perspective and view to the future

(2010) Margaret A. Liu   IMMUNOLOGICAL REVIEWS

Induction of mucosal and systemic antibody and T-cell responses following prime-boost immunization with novel adjuvanted human immunodeficiency virus-1-vaccine formulations

(2010) A. D. Cristillo et al.   JOURNAL OF GENERAL VIROLOGY

Safety and Immunogenicity Study of Multiclade HIV-1 Adenoviral Vector Vaccine Alone or as Boost following a Multiclade HIV-1 DNA Vaccine in Africa

(2010) Walter Jaoko et al.   PLoS One

Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8+ T cells

(2010) G. Nchinda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perforin Expression Directly Ex Vivo by HIV-Specific CD8+ T-Cells Is a Correlate of HIV Elite Control

(2010) Adam R. Hersperger et al.   PLoS Pathogens

The influence of innate and pre-existing immunity on adenovirus therapy

(2009) Anne K. Zaiss et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Electroporation for the Delivery of DNA-based Vaccines and Immunotherapeutics: Current Clinical Developments

(2009) Angela M Bodles-Brakhop et al.   MOLECULAR THERAPY

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Elicitation of broad CTL response against HIV-1 by the DNA vaccine encoding artificial multi-component fusion protein MultiHIV—Study in domestic pigs

(2009) Tarmo Mölder et al.   VACCINE

Induction of HIV-1-specific cellular and humoral immune responses following immunization with HIV-DNA adjuvanted with activated apoptotic lymphocytes

(2009) Andreas Brave et al.   VACCINE

TLR9 as a key receptor for the recognition of DNA☆

(2008) Y KUMAGAI et al.   ADVANCED DRUG DELIVERY REVIEWS

Replicating adenovirus vector prime/protein boost strategies for HIV vaccine development

(2008) L Jean Patterson et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Effects of menstrual cycle on gene transfection through mouse vagina for DNA vaccine

(2008) T. Kanazawa et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses

(2008) Alexandre Harari et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?

(2008) Rafick-Pierre Sekaly   JOURNAL OF EXPERIMENTAL MEDICINE

Broad Immunogenicity of a Multigene, Multiclade HIV‐1 DNA Vaccine Boosted with Heterologous HIV‐1 Recombinant Modified Vaccinia Virus Ankara

(2008) Eric Sandström et al.   JOURNAL OF INFECTIOUS DISEASES

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

DNA vaccines: ready for prime time?

(2008) Michele A. Kutzler et al.   NATURE REVIEWS GENETICS

An HIV Vaccine — Challenges and Prospects

(2008) Margaret I. Johnston et al.   NEW ENGLAND JOURNAL OF MEDICINE

Modifying the HIV-1 env gp160 gene to improve pDNA vaccine-elicited cell-mediated immune responses

(2008) Shakuntala Megati et al.   VACCINE

Intranasal immunization of young mice with a multigene HIV-1 vaccine in combination with the N3 adjuvant induces mucosal and systemic immune responses

(2008) Andreas Bråve et al.   VACCINE

Improved HIV-1 specific T-cell responses by short-interval DNA tattooing as compared to intramuscular immunization in non-human primates

(2008) Babs E. Verstrepen et al.   VACCINE

Increased immune responses in rhesus macaques by DNA vaccination combined with electroporation

(2008) Margherita Rosati et al.   VACCINE

Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime–protein boost HIV-1 vaccine in healthy human volunteers

(2008) Shixia Wang et al.   VACCINE

Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques

(2008) Lauren A. Hirao et al.   VACCINE

Enhancement of Mucosal and Cellular Immune Response in Mice by Vaccination with Respiratory Syncytial Virus DNA Encapsulated with Transfersome

(2008) Jin Xu et al.   VIRAL IMMUNOLOGY