标题
Antibody–drug conjugates – a perfect synergy
作者
关键词
-
出版物
EXPERT OPINION ON BIOLOGICAL THERAPY
Volume 12, Issue 9, Pages 1191-1206
出版商
Informa Healthcare
发表日期
2012-06-01
DOI
10.1517/14712598.2012.693473
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mining human antibody repertoires
- (2014) Roger R. Beerli et al. mAbs
- Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates
- (2012) Ben-Quan Shen et al. NATURE BIOTECHNOLOGY
- Disulfide-Linked Antibody−Maytansinoid Conjugates: Optimization of In Vivo Activity by Varying the Steric Hindrance at Carbon Atoms Adjacent to the Disulfide Linkage
- (2011) Brenda A. Kellogg et al. BIOCONJUGATE CHEMISTRY
- SNAP-Tag Technology Mediates Site Specific Conjugation of Antibody Fragments with a Photosensitizer and Improves Target Specific Phototoxicity in Tumor Cells
- (2011) Ahmad Fawzi Hussain et al. BIOCONJUGATE CHEMISTRY
- Selective Formation of Covalent Protein Heterodimers with an Unnatural Amino Acid
- (2011) Benjamin M. Hutchins et al. CHEMISTRY & BIOLOGY
- Antibody-Drug Conjugates of Calicheamicin Derivative: Gemtuzumab Ozogamicin and Inotuzumab Ozogamicin
- (2011) A. D. Ricart CLINICAL CANCER RESEARCH
- Trastuzumab Emtansine: A Unique Antibody-Drug Conjugate in Development for Human Epidermal Growth Factor Receptor 2-Positive Cancer
- (2011) P. M. LoRusso et al. CLINICAL CANCER RESEARCH
- Antibody Conjugate Therapeutics: Challenges and Potential
- (2011) B. A. Teicher et al. CLINICAL CANCER RESEARCH
- Brentuximab Vedotin (SGN-35)
- (2011) J. Katz et al. CLINICAL CANCER RESEARCH
- Gemtuzumab ozogamicin in non-acute promyelocytic acute myeloid leukemia
- (2011) Marie-Luise Hütter et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Trastuzumab emtansine: a novel antibody-drug conjugate for HER2-positive breast cancer
- (2011) Howard A Burris EXPERT OPINION ON BIOLOGICAL THERAPY
- The development of pyrrolobenzodiazepines as antitumour agents
- (2011) John A Hartley EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Investigational antibody drug conjugates for solid tumors
- (2011) Puja Sapra et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Effect of chelator conjugation level and injection dose on tumor and organ uptake of 111In-labeled MORAb-009, an anti-mesothelin antibody
- (2011) In Soo Shin et al. NUCLEAR MEDICINE AND BIOLOGY
- Bispecific digoxigenin-binding antibodies for targeted payload delivery
- (2011) S. Metz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immunotoxins and Anticancer Drug Conjugate Assemblies: The Role of the Linkage between Components
- (2011) Franco Dosio et al. Toxins
- Ranking the Susceptibility of Disulfide Bonds in Human IgG1 Antibodies by Reduction, Differential Alkylation, and LC−MS Analysis
- (2010) Hongcheng Liu et al. ANALYTICAL CHEMISTRY
- Design and Application of Antibody Cysteine Variants
- (2010) Vladimir Voynov et al. BIOCONJUGATE CHEMISTRY
- Physicochemical Stability of the Antibody−Drug Conjugate Trastuzumab-DM1: Changes due to Modification and Conjugation Processes
- (2010) Aditya A. Wakankar et al. BIOCONJUGATE CHEMISTRY
- Efficient Tumor Targeting with High-Affinity Designed Ankyrin Repeat Proteins: Effects of Affinity and Molecular Size
- (2010) C. Zahnd et al. CANCER RESEARCH
- Antibody-Maytansinoid Conjugates Designed to Bypass Multidrug Resistance
- (2010) Y. V. Kovtun et al. CANCER RESEARCH
- Inotuzumab ozogamicin as novel therapy in lymphomas
- (2010) Bryan Y Wong et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Gemtuzumab ozogamicin for the treatment of acute promyelocytic leukemia: mechanisms of action and resistance, safety and efficacy
- (2010) Massimo Breccia et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Investigational antibody-drug conjugates for hematological malignancies
- (2010) Andrew G Polson et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Brentuximab vedotin: delivering an antimitotic drug to activated lymphoma cells
- (2010) Stephen M Ansell EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Neonatal Fc Receptor: From Immunity to Therapeutics
- (2010) Timothy T. Kuo et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Antibody derivatization and conjugation strategies: Application in preparation of stealth immunoliposome to target chemotherapeutics to tumor
- (2010) Arehalli S. Manjappa et al. JOURNAL OF CONTROLLED RELEASE
- Industrialization of mAb production technology: The bioprocessing industry at a crossroads
- (2010) Brian Kelley mAbs
- Have we overestimated the benefit of human(ized) antibodies?
- (2010) Daniel R. Getts et al. mAbs
- The immunogenicity of humanized and fully human antibodies
- (2010) Fiona A. Harding et al. mAbs
- Antibody−Drug Conjugates: Linking Cytotoxic Payloads to Monoclonal Antibodies
- (2009) Laurent Ducry et al. BIOCONJUGATE CHEMISTRY
- Antibody-Drug Conjugate Targets
- (2009) B. Teicher CURRENT CANCER DRUG TARGETS
- The Versatile MHC Class I-related FcRn Protects IgG and Albumin from Degradation: Implications for Development of New Diagnostics and Therapeutics
- (2009) Jan Terje Andersen et al. Drug Metabolism and Pharmacokinetics
- A modeling analysis of the effects of molecular size and binding affinity on tumor targeting
- (2009) M. M. Schmidt et al. MOLECULAR CANCER THERAPEUTICS
- A simplified suite of methods to evaluate chelator conjugation of antibodies: effects on hydrodynamic radius and biodistribution
- (2009) Fares Al-Ejeh et al. NUCLEAR MEDICINE AND BIOLOGY
- Antibody tumor penetration: Transport opposed by systemic and antigen-mediated clearance
- (2008) Greg M. Thurber et al. ADVANCED DRUG DELIVERY REVIEWS
- Structural and Functional Characterization of Disulfide Isoforms of the Human IgG2 Subclass
- (2008) Thomas M. Dillon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs
- (2008) Jagath R. Junutula et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Engineered anti-CD70 antibody-drug conjugate with increased therapeutic index
- (2008) C. F. McDonagh et al. MOLECULAR CANCER THERAPEUTICS
- Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index
- (2008) Jagath R Junutula et al. NATURE BIOTECHNOLOGY
- An engineered selenocysteine defines a unique class of antibody derivatives
- (2008) T. Hofer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeted Cancer Therapy: Conferring Specificity to Cytotoxic Drugs
- (2007) Ravi V. J. Chari ACCOUNTS OF CHEMICAL RESEARCH
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