Article
Nutrition & Dietetics
Ahad Abdulkarim D. Alharbi, Noriaki Iwamoto, Naoyuki Ebine, Satoshi Nakae, Tatsuya Hojo, Yoshiyuki Fukuoka
Summary: This research examined the effects of single-dose molecular hydrogen (H-2) supplements on acid-base status, muscle deoxygenation, and recovery. The results showed that the HCP group had higher PCO2 and HCO3- concentrations at rest, and during exercise, they exhibited higher peak power and muscle deoxygenation concentration.
Review
Nutrition & Dietetics
Adriano E. Lima-Silva, Gislaine Cristina-Souza, Marcos D. Silva-Cavalcante, Romulo Bertuzzi, David J. Bishop
Summary: Caffeine is widely consumed as an ergogenic aid for exercise performance, with its stimulatory effect on the central nervous system being a key mechanism. However, caffeine may also have direct effects on other physiological systems like the pulmonary, cardiovascular, and muscular systems during high-intensity whole-body exercise. Understanding these multiple effects of caffeine could potentially expand its use in different sporting contexts and aid in the treatment of certain diseases.
Article
Neurosciences
Benoit Smeuninx, Yasir S. Elhassan, Elizabeth Sapey, Alison B. Rushton, Paul T. Morgan, Marie Korzepa, Archie E. Belfield, Andrew Philp, Matthew S. Brook, Nima Gharahdaghi, Daniel Wilkinson, Kenneth Smith, Philip J. Atherton, Leigh Breen
Summary: This study found that prior resistance exercise can attenuate the impairment of myofibrillar protein synthesis during bed rest in older adults, reducing muscle loss and improving overall health outcomes.
JOURNAL OF PHYSIOLOGY-LONDON
(2023)
Article
Nutrition & Dietetics
Ahad Abdulkarim D. Alharbi, Naoyuki Ebine, Satoshi Nakae, Tatsuya Hojo, Yoshiyuki Fukuoka
Summary: The study showed that supplementation with HCP led to decreased muscle oxygenation, impacting the pH levels and balance between oxygen delivery and utilization during exercise.
Article
Multidisciplinary Sciences
Sarah Gephine, Patrick Mucci, Mathieu Bielmann, Mickael Martin, Laurent Bouyer, Didier Saey, Francois Maltais
Summary: In this study, the oxygenation and electromyography responses in the quadriceps during the 1-min sit-to-stand (1STS) were compared between individuals with severe COPD and controls. The results showed that individuals with COPD had a slower rate of sit-to-stand maneuvers, resulting in less total work compared to controls. During the recovery period, individuals with COPD exhibited larger overshoots in oxygenation parameters. Additionally, only individuals with COPD showed signs of a fatiguing contraction pattern in the quadriceps.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Robson F. Borges, Gaspar R. Chiappa, Paulo T. Muller, Alexandra Correa Gervazoni Balbuena de Lima, Lawrence Patrick Cahalin, Graziella Franca Bernardelli Cipriano, Gerson Cipriano
Summary: Moderate-intensity BFR training prior to a high-intensity exercise did not accelerate subsequent VO2P and Q(T) kinetics, but significantly improved exercise tolerance and work efficiency, resulting in lower oxygen cost.
Article
Multidisciplinary Sciences
Anita B. Marostegan, Claudio A. Gobatto, Felipe M. Rasteiro, Charlini S. Hartz, Marlene A. Moreno, Fulvia B. Manchado-Gobatto
Summary: This study aimed to investigate the effects of three different inspiratory muscle warm-up (IMW) loads using a shorter protocol on mechanical, physiological and muscle oxygenation responses during and after high-intensity running exercise. The results showed that IMW loads can enhance running power and force, but did not significantly improve performance assessed second by second. In addition, 40% of maximal inspiratory pressure (MIP) improved tissue saturation index (TSI) of the biceps brachii (BB) during the recovery phase.
SCIENTIFIC REPORTS
(2022)
Article
Nutrition & Dietetics
Tomoka Matsuda, Hideyuki Takahashi, Mariko Nakamura, Moe Kanno, Hazuki Ogata, Akira Ishikawa, Mizuki Yamada, Kayoko Kamemoto, Mikako Sakamaki-Sunaga
Summary: The present study investigated the effects of the menstrual cycle on muscle glycogen and circulating substrates during high-intensity intermittent exercise until exhaustion in healthy women who habitually exercised. The results showed that although exercise time does not change with the menstrual cycle, the menstrual cycle influences the utilization of muscle glycogen.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2022)
Article
Geriatrics & Gerontology
James E. M. Blackwell, Nima Gharahdaghi, Matthew S. Brook, Shinya Watanabe, Catherine L. Boereboom, Brett Doleman, Jonathan N. Lund, Daniel J. Wilkinson, Kenneth Smith, Philip J. Atherton, John P. Williams, Bethan E. Phillips
Summary: The study found that in octogenarians with comorbidities, high-intensity interval training (HIIT) can improve cardiorespiratory fitness and muscle mass, including reducing fat mass and increasing muscle synthesis rates.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2021)
Article
Physiology
Kevin J. Grossman, David J. Lim, Juan M. Murias, Glen R. Belfry
Summary: The study compared the effects of regulated breathing and free breathing on respiratory and muscle deoxygenation responses during different exercise conditions, showing differences in oxygen uptake and muscle oxygenation in various exercise scenarios.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Biology
Morten Hostrup, Anders Krogh Lemminger, Ben Stocks, Alba Gonzalez-Franquesa, Jeppe Kjaergaard Larsen, Julia Prats Quesada, Martin Thomassen, Brian Tate Weinert, Jens Bangsbo, Atul Shahaji Deshmukh, David E. James
Summary: Exercise is effective in preventing and treating metabolic diseases. High-intensity interval training (HIIT) can induce changes in the proteome and acetylome of human skeletal muscle, leading to metabolic adaptations. Furthermore, HIIT increases the acetylation of mitochondrial proteins.
Article
Biochemistry & Molecular Biology
Ethan L. Ostrom, Ana P. Valencia, David J. Marcinek, Tinna Traustadottir
Summary: High intensity exercise significantly impacts Nrf2-ARE binding and Keap1 protein expression in mouse skeletal muscle, while low intensity exercise does not show significant effects on these factors. This suggests that the intensity of exercise plays a role in activating redox signaling pathways in skeletal muscle.
FREE RADICAL BIOLOGY AND MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Macsue Jacques, Shanie Landen, Javier Alvarez Romero, Danielle Hiam, Ralf B. Schittenhelm, Iresha Hanchapola, Anup D. Shah, Sarah Voisin, Nir Eynon
Summary: Exercise has significant effects on both the epigenome and proteome in human muscle. A 12-week high-intensity interval training intervention was conducted on 16 healthy moderately trained males, and muscle biopsies were collected at baseline and after 4, 8, and 12 weeks. The study found significant changes in proteins and DNA methylation levels, with some proteins consistently changed across individuals and the discovery of two novel exercise-related proteins. These findings contribute to a better understanding of the impact of exercise on the human body.
Article
Cell Biology
Marco Ponzetti, Federica Aielli, Argia Ucci, Alfredo Cappariello, Giovanni Lombardi, Anna Teti, Nadia Rucci
Summary: LCN2 may negatively affect muscle physiology after high-intensity exercise, as seen in global knockout Lcn2(-/-) mice which exhibited differences in some aspects compared to wild type mice.
JOURNAL OF CELLULAR PHYSIOLOGY
(2022)
Article
Physiology
Norita Gildea, Adam McDermott, Joel Rocha, Donal O'Shea, Simon Green, Mikel Egana
Summary: Both low-volume high-intensity interval training (HIIT) and moderate-intensity continuous endurance training (MICT) improved peak oxygen uptake (V O2peak) in adults with uncomplicated type 2 diabetes in a similar time course, with likely improvements due to enhanced microvascular oxygen delivery.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
(2021)
Review
Behavioral Sciences
Jon Fulford, Fraser Milton, David Salas, Alicia Smith, Amber Simler, Crawford Winlove, Adam Zeman
Article
Physiology
Ida E. Clark, Richie P. Goulding, Fred J. DiMenna, Stephen J. Bailey, Martin I. Jones, Jonathan Fulford, Sinead T. J. McDonagh, Andrew M. Jones, Anni Vanhatalo
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2019)
Article
Physiology
Zainie Aboo Bakkar, Jonathan Fuford, Phillip E. Gates, Sarah R. Jackman, Andrew M. Jones, Bert Bond, Joanna L. Bowtell
JOURNAL OF APPLIED PHYSIOLOGY
(2019)
Review
Sport Sciences
Matthew Campbell, Jo Varley-Campbell, Jon Fulford, Bryan Taylor, Katya N. Mileva, Joanna L. Bowtell
Article
Physiology
Paul T. Morgan, Stephen J. Bailey, Rhys A. Banks, Jonathan Fulford, Anni Vanhatalo, Andrew M. Jones
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
(2019)
Correction
Sport Sciences
Matthew Campbell, Jo Varley-Campbell, Jon Fulford, Bryan Taylor, Katya N. Mileva, Joanna L. Bowtell
Article
Orthopedics
Christine J. Heales, Ian R. Summers, Jonathan Fulford, Karen M. Knapp, C. Peter Winlove
BMC MUSCULOSKELETAL DISORDERS
(2019)
Article
Endocrinology & Metabolism
Sean P. Kilroe, Jonathan Fulford, Andrew M. Holwerda, Sarah R. Jackman, Benjamin P. Lee, Annemie P. Gijsen, Luc J. C. van Loon, Benjamin T. Wall
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
(2020)
Article
Sport Sciences
Sean P. Kilroe, Jonathan Fulford, Sarah R. Jackman, Luc J. C. Van Loon, Benjamin T. Wall
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
(2020)
Article
Sport Sciences
Owen William Tomlinson, Alan Robert Barker, Jonathan Fulford, Paul Wilson, Patrick John Oades, Craig Anthony Williams
EUROPEAN JOURNAL OF SPORT SCIENCE
(2020)
Article
Physiology
Luke J. Connolly, Suzanne Scott, Carmelina M. Morencos, Jonathan Fulford, Andrew M. Jones, Karen Knapp, Peter Krustrup, Stephen J. Bailey, Joanna L. Bowtell
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2020)
Article
Biophysics
M. A. Ellison, M. Kenny, J. Fulford, A. Javadi, H. M. Rice
JOURNAL OF BIOMECHANICS
(2020)
Article
Sport Sciences
Colin Farr, Andrew R. Middlebrooke, Neil Armstrong, Alan R. Barker, Jon Fulford, David M. Mawson, Ali M. McManus
JOURNAL OF SPORTS SCIENCE AND MEDICINE
(2019)
Article
Urology & Nephrology
Rhian L. Clissold, Jon Fulford, Michelle Hudson, Beverley M. Shields, Timothy J. McDonald, Sian Ellard, Andrew T. Hattersley, Coralie Bingham
CLINICAL KIDNEY JOURNAL
(2018)
Article
Nutrition & Dietetics
Joanna L. Bowtell, Magni Mohr, Jonathan Fulford, Sarah R. Jackman, Georgios Ermidis, Peter Krustrup, Katya N. Mileva
FRONTIERS IN NUTRITION
(2018)