Amelioration of Glucolipotoxicity-Induced Endoplasmic Reticulum Stress by a “Chemical Chaperone” in Human THP-1 Monocytes

Calcium entry via TRPC6 mediates albumin overload-induced endoplasmic reticulum stress and apoptosis in podocytes

(2011) Shan Chen et al.   CELL CALCIUM

Sodium Phenylbutyrate, a Drug With Known Capacity to Reduce Endoplasmic Reticulum Stress, Partially Alleviates Lipid-Induced Insulin Resistance and β-Cell Dysfunction in Humans

(2011) Changting Xiao et al.   DIABETES

The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes

(2011) M. Shimoda et al.   DIABETOLOGIA

Endoplasmic reticulum stress induces retinal endothelial permeability of extracellular-superoxide dismutase

(2011) Tetsuo Adachi et al.   FREE RADICAL RESEARCH

Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma

(2011) Gulab S. Zode et al.   JOURNAL OF CLINICAL INVESTIGATION

Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes

(2011) M. Balasubramanyam et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The emerging role of autophagy in the pathophysiology of diabetes mellitus

(2010) Claudio D. Gonzalez et al.   Autophagy

The Role of Endoplasmic Reticulum Stress in the Progression of Atherosclerosis

(2010) Ira Tabas   CIRCULATION RESEARCH

High Glucose-Induced Oxidative Stress Increases Transient Receptor Potential Channel Expression in Human Monocytes

(2010) T. Wuensch et al.   DIABETES

Evidence for Unfolded Protein Response Activation in Monocytes from Individuals with  -1 Antitrypsin Deficiency

(2010) T. P. Carroll et al.   JOURNAL OF IMMUNOLOGY

Attenuation of diabetic nephropathy in diabetes rats induced by streptozotocin by regulating the endoplasmic reticulum stress inflammatory response

(2010) Wei Qi et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

TRP channels and their implications in metabolic diseases

(2010) Zhiming Zhu et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Effects of 4-phenylbutyric acid on the process and development of diabetic nephropathy induced in rats by streptozotocin: Regulation of endoplasmic reticulum stress-oxidative activation

(2010) Zhi-Feng Luo et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Life and death partners: apoptosis, autophagy and the cross-talk between them

(2009) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

Reduced Apoptosis and Plaque Necrosis in Advanced Atherosclerotic Lesions of Apoe−/− and Ldlr−/− Mice Lacking CHOP

(2009) Edward Thorp et al.   Cell Metabolism

CD14+ Monocytes Are Vulnerable and Functionally Impaired Under Endoplasmic Reticulum Stress in Patients With Type 2 Diabetes

(2009) T. Komura et al.   DIABETES

Diabetes modulates capacitative calcium entry and expression of transient receptor potential canonical channels in human saphenous vein

(2009) Ada W.Y. Chung et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response

(2009) Sana Basseri et al.   JOURNAL OF LIPID RESEARCH

Molecular convergence of hexosamine biosynthetic pathway and ER stress leading to insulin resistance in L6 skeletal muscle cells

(2009) V. Srinivasan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis

(2009) Ebru Erbay et al.   NATURE MEDICINE

Phenylbutyrate Ameliorates Cognitive Deficit and Reduces Tau Pathology in an Alzheimer's Disease Mouse Model

(2009) Ana Ricobaraza et al.   NEUROPSYCHOPHARMACOLOGY

A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human α-synuclein A30P+A53T transgenic mice

(2009) Kazuhiko Ono et al.   PARKINSONISM & RELATED DISORDERS

Glucose Amplifies Fatty Acid-Induced Endoplasmic Reticulum Stress in Pancreatic β-Cells via Activation of mTORC1

(2009) Etti Bachar et al.   PLoS One

A chemical chaperone 4-PBA ameliorates palmitate-induced inhibition of glucose-stimulated insulin secretion (GSIS)

(2008) Sung-E Choi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

TRPC channels and store-operated Ca2+ entry

(2008) Ginés M. Salido et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Role for Endoplasmic Reticulum Stress in Diabetes Mellitus

(2008) Décio L. Eizirik et al.   ENDOCRINE REVIEWS

Glucolipotoxicity: Fuel Excess and β-Cell Dysfunction

(2008) Vincent Poitout et al.   ENDOCRINE REVIEWS