期刊
EXPERIMENTAL DERMATOLOGY
卷 23, 期 5, 页码 295-303出版社
WILEY-BLACKWELL
DOI: 10.1111/exd.12370
关键词
fillers; hyaluronan; metabolism; skin; skin regeneration
类别
资金
- Berliner Stiftung Dermatologie
- Deutsche Forschungsgemeinschaft [SFB TRR67]
In recent years, hyaluronan (HA) has become an increasingly attractive substance as a non-immunogenic filler and scaffolding material in cosmetic dermatology. Despite its wide use for skin augmentation and rejuvenation, relatively little is known about the molecular structures and interacting proteins of HA in normal and diseased skin. However, a comprehensive understanding of cutaneous HA homeostasis is required for future the development of HA-based applications for skin regeneration. This review provides an update on HA-based structures, expression, metabolism and its regulation, function and pharmacological targeting of HA in skin.
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