A microphysiological system model of therapy for liver micrometastases

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

(2013) Patricio Godoy et al.   ARCHIVES OF TOXICOLOGY

The pre-metastatic niche: finding common ground

(2013) Jaclyn Sceneay et al.   CANCER AND METASTASIS REVIEWS

Patient-Derived Tumor Xenografts: Transforming Clinical Samples into Mouse Models

(2013) D. Siolas et al.   CANCER RESEARCH

The Emerging Role of Immunosurveillance in Dictating Metastatic Spread in Breast Cancer

(2013) C. Y. Slaney et al.   CANCER RESEARCH

Modeling Boundary Conditions for Balanced Proliferation in Metastatic Latency

(2013) D. P. Taylor et al.   CLINICAL CANCER RESEARCH

Influence of tumour micro-environment heterogeneity on therapeutic response

(2013) Melissa R. Junttila et al.   NATURE

Liver sinusoidal endothelial cells contribute to CD8 T cell tolerance toward circulating carcinoembryonic antigen in mice

(2012) Bastian Höchst et al.   HEPATOLOGY

Hedgehog signaling in myofibroblasts directly promotes prostate tumor cell growth

(2012) Maribella Domenech et al.   Integrative Biology

A sensitive and specific CYP cocktail assay for the simultaneous assessment of human cytochrome P450 activities in primary cultures of human hepatocytes using LC–MS/MS

(2012) Venkateswaran C. Pillai et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy

(2012) C. Lee et al.   Science Translational Medicine

Lactate: A Metabolic Key Player in Cancer

(2011) F. Hirschhaeuser et al.   CANCER RESEARCH

Hepatocyte induced re-expression of E-cadherin in breast and prostate cancer cells increases chemoresistance

(2011) Yvonne Chao et al.   CLINICAL & EXPERIMENTAL METASTASIS

Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer

(2011) Michael K. Wendt et al.   MOLECULAR BIOLOGY OF THE CELL

Stress hormones increase cell proliferation and regulates interleukin-6 secretion in human oral squamous cell carcinoma cells

(2010) Daniel G. Bernabé et al.   BRAIN BEHAVIOR AND IMMUNITY

Metastatic Growth from Dormant Cells Induced by a Col-I-Enriched Fibrotic Environment

(2010) D. Barkan et al.   CANCER RESEARCH

Proteolytic Activity Matrix Analysis (PrAMA) for simultaneous determination of multiple protease activities

(2010) Miles A. Miller et al.   Integrative Biology

Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition

(2010) Yvonne L Chao et al.   Molecular Cancer

Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia

(2010) Todd W Ridky et al.   NATURE MEDICINE

Microfluidic Culture Models of Tumor Angiogenesis

(2010) Abraham D. Stroock et al.   TISSUE ENGINEERING PART A

Hepatic Stellate Cells Promote Liver Metastasis of Colon Cancer Cells by the Action of SDF-1/CXCR4 Axis

(2009) Ryo Matsusue et al.   ANNALS OF SURGICAL ONCOLOGY

The Liver as a Lymphoid Organ

(2009) Ian Nicholas Crispe   Annual Review of Immunology

A microfluidic hepatic coculture platform for cell-based drug metabolism studies

(2009) Eric Novik et al.   BIOCHEMICAL PHARMACOLOGY

Liver tissue engineering in the evaluation of drug safety

(2009) Ajit Dash et al.   Expert Opinion on Drug Metabolism & Toxicology

Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor β-induced apoptosis

(2009) Patricio Godoy et al.   HEPATOLOGY

Role of Kupffer cells in the outgrowth of colorectal cancer liver metastases

(2009) Konstantinos A. Paschos et al.   HEPATOLOGY RESEARCH

A micro cell culture analog (µCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs

(2009) Jong Hwan Sung et al.   LAB ON A CHIP

The many faces of tumor dormancy

(2008) ROBERT A. WEINBERG   APMIS

E-cadherin as an indicator of mesenchymal to epithelial reverting transitions during the metastatic seeding of disseminated carcinomas

(2008) Alan Wells et al.   CLINICAL & EXPERIMENTAL METASTASIS

Three-dimensional context regulation of metastasis

(2008) Janine T. Erler et al.   CLINICAL & EXPERIMENTAL METASTASIS

The role of matrix stiffness in regulating cell behavior

(2008) Rebecca G. Wells   HEPATOLOGY

An integrated comparative phosphoproteomic and bioinformatic approach reveals a novel class of MPM-2 motifs upregulated in EGFRvIII-expressing glioblastoma cells

(2008) Brian A. Joughin et al.   Molecular BioSystems

3-D Tumor Model forIn VitroEvaluation of Anticancer Drugs

(2008) Jayme L. Horning et al.   MOLECULAR PHARMACEUTICS

Endothelial Progenitor Cells Control the Angiogenic Switch in Mouse Lung Metastasis

(2008) D. Gao et al.   SCIENCE