VER-155008, a small molecule inhibitor of HSP70 with potent anti-cancer activity on lung cancer cell lines

The HSP70 family and cancer

(2013) M. E. Murphy   CARCINOGENESIS

Hsp70 silencing with siRNA in nanocarriers enhances cancer cell death induced by the inhibitor of Hsp90

(2013) Mirela Matokanovic et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

The PI3K/Akt signaling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival in multiple myeloma

(2013) M. Chatterjee et al.   HAEMATOLOGICA

Disease-stabilizing treatment with all-trans retinoic acid and valproic acid in acute myeloid leukemia: Serum hsp70 and hsp90 levels and serum cytokine profiles are determined by the disease, patient age, and anti-leukemic treatment

(2012) Hanne Fredly et al.   AMERICAN JOURNAL OF HEMATOLOGY

Discrimination of clinical stages in non-small cell lung cancer patients by serum HSP27 and HSP70: A multi-institutional case–control study

(2012) Matthias Zimmermann et al.   CLINICA CHIMICA ACTA

RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation

(2011) Naomi Walsh et al.   CANCER LETTERS

Co-Inhibition of HSP70/HSP90 Synergistically Sensitizes Nasopharyngeal Carcinoma Cells to Thermotherapy

(2011) Xiao-bo Cui et al.   INTEGRATIVE CANCER THERAPIES

Antileukemic activity of the HSP70 inhibitor pifithrin-μ in acute leukemia

(2011) M Kaiser et al.   Blood Cancer Journal

Increased expression of co-chaperone HOP with HSP90 and HSC70 and complex formation in human colonic carcinoma

(2010) Hiroshi Kubota et al.   CELL STRESS & CHAPERONES

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

ATPases as Drug Targets: Insights from Heat Shock Proteins 70 and 90

(2010) Andrew J. Massey   JOURNAL OF MEDICINAL CHEMISTRY

EGFR Signaling and Drug Discovery

(2010) Georg Lurje et al.   ONCOLOGY

A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells

(2009) Andrew J. Massey et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Novel Adenosine-Derived Inhibitors of 70 kDa Heat Shock Protein, Discovered Through Structure-Based Design†

(2009) Douglas S. Williamson et al.   JOURNAL OF MEDICINAL CHEMISTRY