Palladium-Catalyzed α-Arylation Reactions in Total Synthesis

Enantioselective Total Synthesis of Dysidavarone A, a Novel Sesquiterpenoid Quinone from the Marine SpongeDysidea avara

(2014) Yurie Fukui et al.   CHEMISTRY-A EUROPEAN JOURNAL

Protecting-Group-Free Synthesis of Taiwaniaquinone H Using a One-Pot Thermal Ring Expansion/4π-Electrocyclization Strategy

(2014) Xiuxiang Yan et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis and Antibacterial Activity of Dysidavarone A

(2013) Björn Schmalzbauer et al.   ORGANIC LETTERS

Development of a Scalable Route to a Dual NK-1/Serotonin Receptor Antagonist

(2013) Christina Risatti et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Development of a scalable palladium-catalyzed α-arylation process for the synthesis of a CGRP antagonist

(2013) Lopa V. Desai et al.   TETRAHEDRON

Direct Copper-Catalyzed α-Arylation of Benzyl Phenyl Ketones with Aryl Iodides: Route towards Tamoxifen

(2012) Grégory Danoun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Cross-Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize

(2012) Carin C. C. Johansson Seechurn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective construction of sterically hindered tertiary α-aryl ketones: a catalytic asymmetric synthesis of isoflavanones

(2012) Michael P. Carroll et al.   CHEMICAL COMMUNICATIONS

An Expeditious Synthesis of the MDM2–p53 Inhibitor AM-8553

(2012) Brian S. Lucas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient and Scalable Enantioselective Synthesis of a CGRP Antagonist

(2012) David K. Leahy et al.   ORGANIC LETTERS

Initial Process Development and Scale-Up of the Synthesis of a Triple Reuptake Inhibitor ALB 109780

(2012) Qiang Yang et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Synthesis of substituted isoquinolines utilizing palladium-catalyzed  -arylation of ketones

(2012) T. J. Donohoe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of BMS-846372, a Potent and Orally Active Human CGRP Receptor Antagonist for the Treatment of Migraine

(2012) Guanglin Luo et al.   ACS Medicinal Chemistry Letters

Core Modification of Cytisine: A Modular Synthesis

(2011) Christoph Hirschhäuser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and synthesis of a novel, orally active, brain penetrant, tri-substituted thiophene based JNK inhibitor

(2011) Simeon Bowers et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Stereoselective Palladium-Catalyzed α-Arylation of 3-Aryl-1-Indanones: An Asymmetric Synthesis of (+)-Pauciflorol F

(2011) Bong Hyang Lee et al.   JOURNAL OF ORGANIC CHEMISTRY

A Concise Synthesis of Paucifloral F and Related Indanone Analogues via Palladium-Catalyzed α-Arylation

(2011) Yang Yang et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis ofN-Methylwelwitindolinone D Isonitrile

(2011) Vikram Bhat et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Total Syntheses of (−)-Taiwaniaquinone H and (−)-Taiwaniaquinol B by Iridium-Catalyzed Borylation and Palladium-Catalyzed Asymmetric α-Arylation

(2011) Xuebin Liao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Unified Route to the Welwitindolinone Alkaloids: Total Syntheses of (−)-N-Methylwelwitindolinone C Isothiocyanate, (−)-N-Methylwelwitindolinone C Isonitrile, and (−)-3-Hydroxy-N-methylwelwitindolinone C Isothiocyanate

(2011) Kevin M. Allan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient synthesis of esermethole and its analogues

(2011) Yongyun Zhou et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Dysidavarones A–D, New Sesquiterpene Quinones from the Marine Sponge Dysidea avara

(2011) Wei-Hua Jiao et al.   ORGANIC LETTERS

A robust and scalable synthesis of the potent neuroprotective agent (−)-huperzine A

(2011) Maung Kyaw Moe Tun et al.   Chemical Science

Metal-Catalyzed α-Arylation of Carbonyl and Related Molecules: Novel Trends in CC Bond Formation by CH Bond Functionalization

(2010) Carin C. C. Johansson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Direct Arylation of 4-Chromanones: Selective Synthesis of Racemic Isoflavanones and 3,3-Diaryl-4-chromanones

(2010) Fabio Bellina et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Dibenzazepinones by Palladium-Catalyzed Intramolecular Arylation ofo-(2′-Bromophenyl)anilide Enolates

(2010) Xiaohong Pan et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd-Catalyzed Assembly of Spirooxindole Natural Products: A Short Synthesis of Horsfiline

(2010) Nina Deppermann et al.   JOURNAL OF ORGANIC CHEMISTRY

Concise Total Synthesis of (±)-Lycopladine A

(2010) John E. DeLorbe et al.   ORGANIC LETTERS

Efficient Asymmetric Synthesis ofabeo-Abietane-Type Diterpenoids by Using the Intramolecular Heck Reaction

(2009) Manabu Node et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis of Diverse Carbogenic Complexity within the Resveratrol Class from a Common Building Block

(2009) Scott A. Snyder et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Concise Synthesis of Pauciflorol F Using a Larock Annulation

(2009) Jenna L. Jeffrey et al.   ORGANIC LETTERS

Palladium-Catalyzed α-Arylation of Aldehydes with Bromo- and Chloroarenes Catalyzed by [{Pd(allyl)Cl}2] and dppf or Q-phos

(2008) Giang D. Vo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Improved Protocol for the Pd-Catalyzed α-Arylation of Aldehydes with Aryl Halides

(2008) Rubén Martín et al.   ORGANIC LETTERS

Tunable Palladium-FibreCats for Aryl Chloride Suzuki Coupling with Minimal Metal Leaching

(2008) Thomas J. Colacot et al.   ORGANOMETALLICS