The Alternative Route to Enantiopure Multicomponent Reaction Products: Biocatalytic or Organocatalytic Enantioselective Production of Inputs for Multicomponent Reactions

SYNTHESIS OF TERT-BUTYL (1S,2S)-2-METHYL-3-OXO-1-PHENYLPROPYLCARBAMATE BY ASYMMETRIC MANNICH REACTION

(2014)   ORGANIC SYNTHESES

Trypsin-Catalyzed One-Pot Multicomponent Synthesis of 4-Thiazolidinones

(2013) Hui Zheng et al.   CATALYSIS LETTERS

Thehomo-PADAM Protocol: Stereoselective and Operationally Simple Synthesis of α-Oxo- or α-Hydroxy-γ-acylaminoamides and Chromanes

(2013) Fabio Morana et al.   CHEMISTRY-A EUROPEAN JOURNAL

Long-Range Diastereoselectivity in an Ugi Reaction: Stereocontrolled and Diversity-Oriented Synthesis of Tetrahydrobenzoxazepines

(2013) Luca Banfi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Multicomponent synthesis of dihydropyrano[2,3-c]pyrazoles catalyzed by lipase from Aspergillus niger

(2013) Pranjal P. Bora et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Saccharomyces cerevisiae catalyzed one pot synthesis of isoindolo[2,1-a]quinazoline performed under ultrasonication

(2013) Jemin R. Avalani et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Enantio- and Diastereoselective Synthesis of Highly Substituted Benzazepines by a Multicomponent Strategy Coupled with Organocatalytic and Enzymatic Procedures

(2013) Lisa Moni et al.   JOURNAL OF ORGANIC CHEMISTRY

Model Studies on the First Enzyme-Catalyzed Ugi Reaction

(2013) Szymon Kłossowski et al.   ORGANIC LETTERS

On the Probability That Ring-Forming Multicomponent Reactions Are Intrinsically Green: Setting Thresholds for Intrinsic Greenness Based on Design Strategy and Experimental Reaction Performance

(2013) John Andraos   ACS Sustainable Chemistry & Engineering

Organocatalytic Asymmetric Synthesis of β-Aryl-β-isocyano Esters

(2012) Fabio Morana et al.   ADVANCED SYNTHESIS & CATALYSIS

Biocatalysts for multicomponent Biginelli reaction: bovine serum albumin triggered waste-free synthesis of 3,4-dihydropyrimidin-2-(1H)-ones

(2012) Upendra K. Sharma et al.   AMINO ACIDS

Stereocontrolled Domino Reactions

(2012) Hélène Pellissier   CHEMICAL REVIEWS

Chemistry and Biology Of Multicomponent Reactions

(2012) Alexander Dömling et al.   CHEMICAL REVIEWS

Recent developments in asymmetric multicomponent reactions

(2012) Corien de Graaff et al.   CHEMICAL SOCIETY REVIEWS

Multicomponent and sequential organocatalytic reactions: diversity with atom-economy and enantiocontrol

(2012) Charles M. Marson   CHEMICAL SOCIETY REVIEWS

Recent Advances in Asymmetric Isocyanide-Based Multicomponent Reactions

(2012) Sander S. van Berkel et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic asymmetric epoxidation and tandem epoxidation/Passerini reaction under eco-friendly reaction conditions

(2012) Anna Maria Deobald et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Development of a stereoselective Ugi reaction starting from an oxanorbornene β-amino acid derivative

(2012) Luca Banfi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

“Extreme” Ugi Reactions With Some Complex α-Amino Acids

(2012) Charles Dylan Turner et al.   ORGANIC LETTERS

A novel sugar based intramolecular Ugi 3CC for the N-alkyl-3-oxo-4-aryl-octahydrofuro[2,3-f][1,4]oxazepine-5-carboxamides

(2012) B.V. Subba Reddy et al.   TETRAHEDRON LETTERS

Recent applications of multicomponent reactions in medicinal chemistry

(2012) Paul Slobbe et al.   MedChemComm

Long-range diastereoselectivity in Ugi reactions of 2-substituted dihydrobenzoxazepines

(2011) Luca Banfi et al.   Beilstein Journal of Organic Chemistry

Recyclable Tertiary Amine Modified Diarylprolinol Ether as Aminocatalyst for the Sequential Asymmetric Synthesis of Functionalized Cyclohexanes and Chromenes

(2011) Hao Shen et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

One-Pot Synthesis of Dihydropyrimidiones via Environmentally Friendly Enzyme-Catalyzed Biginelli Reaction

(2011) Pengfei Zhang et al.   HETEROCYCLES

Enantioselective Organocatalytic Friedel–Crafts Alkylation Reaction of Indoles with 5-Hydroxyfuran-2(5H)-one: Access to Chiral γ-Lactones and γ-Lactams via a Ugi 4-Center 3-Component Reaction

(2011) Emmanuel Riguet   JOURNAL OF ORGANIC CHEMISTRY

Investigation of the Configurational Stabilities of Chiral Isocyanoacetates in Multicomponent Reactions

(2011) Daniel W. Carney et al.   JOURNAL OF ORGANIC CHEMISTRY

A Microwave-Assisted Diastereoselective Multicomponent Reaction To Access Dibenzo[c,e]azepinones: Synthesis and Biological Evaluation

(2011) Vaibhav P. Mehta et al.   JOURNAL OF ORGANIC CHEMISTRY

Stereoselective synthesis of N-aryl proline amides by biotransformation–Ugi-Smiles sequence

(2011) Anass Znabet et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Diversity oriented and chemoenzymatic synthesis of densely functionalized pyrrolidines through a highly diastereoselective Ugi multicomponent reaction

(2011) Valentina Cerulli et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Elaboration of Peptidomimetics Derived from a PADAM Approach: Synthesis of Polyfunctionalised 2(1H)-Pyrazinones via an Unexpected Aromatisation

(2011) Andrea Basso et al.   SYNLETT

Synthesis of β-lactam peptidomimetics through Ugi MCR: first application of chiral Nβ-Fmoc amino alkyl isonitriles in MCRs

(2011) T.M. Vishwanatha et al.   TETRAHEDRON LETTERS

A highly efficient synthesis of telaprevir by strategic use of biocatalysis and multicomponent reactions

(2010) Anass Znabet et al.   CHEMICAL COMMUNICATIONS

Asymmetric synthesis of synthetic alkaloids by a tandem biocatalysis/Ugi/Pictet–Spengler-type cyclization sequence

(2010) Anass Znabet et al.   CHEMICAL COMMUNICATIONS

Multicomponent Reactions for the Synthesis of Heterocycles

(2010) Bo Jiang et al.   Chemistry-An Asian Journal

Recent advances in multicomponent reactions for diversity-oriented synthesis

(2010) James E. Biggs-Houck et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A Marriage of Convenience: Combining the Power of Isocyanide-Based Multicomponent Reactions with the Versatility of (Hetero)norbornene Chemistry

(2010) Andrea Basso et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

On the industrial applications of MCRs: molecular diversity in drug discovery and generic drug synthesis

(2010) Cédric Kalinski et al.   MOLECULAR DIVERSITY

Stereochemical and Skeletal Diversity Arising from Amino Propargylic Alcohols

(2010) Daniela Pizzirani et al.   ORGANIC LETTERS

Expanding Stereochemical and Skeletal Diversity Using Petasis Reactions and 1,3-Dipolar Cycloadditions

(2010) Giovanni Muncipinto et al.   ORGANIC LETTERS

Natural Product Synthesis Using Multicomponent Reaction Strategies

(2009) Barry B. Touré et al.   CHEMICAL REVIEWS

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Multicomponent synthesis of dihydrobenzoxazepinones, bearing four diversity points, as potential α-helix mimics

(2009) Luca Banfi et al.   MOLECULAR DIVERSITY

Emerging molecular diversity from the intra-molecular Ugi reaction: iterative efficiency in medicinal chemistry

(2009) Christopher Hulme et al.   MOLECULAR DIVERSITY

Passerini Reaction−Amine Deprotection−Acyl Migration Peptide Assembly: Efficient Formal Synthesis of Cyclotheonamide C

(2009) Sophie Faure et al.   ORGANIC LETTERS

Three-component Ugi–Smiles couplings of cyclic imines

(2009) Laurent El Kaïm et al.   TETRAHEDRON LETTERS

Isocyanide-based multicomponent reactions in drug discovery

(2008) Irini Akritopoulou-Zanze   CURRENT OPINION IN CHEMICAL BIOLOGY

A convergent synthesis of enantiopure bicyclic scaffolds through multicomponent Ugi reaction

(2007) Luca Banfi et al.   TETRAHEDRON