Late-Stage C-H Bond Arylation of Spirocyclic σ1Ligands for Analysis of Complementary σ1Receptor Surface

Pharmacophore Models and Development of Spirocyclic Ligands for σ1 Receptors

(2012) Bernhard Wunsch   CURRENT PHARMACEUTICAL DESIGN

Design, synthesis and pharmacological evaluation of spirocyclic σ1 receptor ligands with exocyclic amino moiety (increased distance 1)

(2011) Elisabeth Rack et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Exploitation of an additional hydrophobic pocket of σ1 receptors: Late-stage diverse modifications of spirocyclic thiophenes by C–H bond functionalization

(2011) Christina Meyer et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Palladium/2,2′-bipyridyl/Ag2CO3 catalyst for C–H bond arylation of heteroarenes with haloarenes

(2011) Shuichi Yanagisawa et al.   TETRAHEDRON

5D-QSAR for spirocyclic σ1 receptor ligands by Quasar receptor surface modeling

(2010) Christoph Oberdorf et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of spirocyclic σ1 receptor ligands as potential PET radiotracers, structure–affinity relationships and in vitro metabolic stability

(2009) Eva Große Maestrup et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Pharmacology and Therapeutic Potential of Sigma1 Receptor Ligands

(2009) E. Cobos et al.   Current Neuropharmacology

Dancing of the Second Aromatic Residue around the 6,8-Diazabicyclo[3.2.2]nonane Framework: Influence on σ Receptor Affinity and Cytotoxicity

(2009) Ralph Holl et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Biological Evaluation, and Three-Dimensional in Silico Pharmacophore Model for σ1Receptor Ligands Based on a Series of Substituted Benzo[d]oxazol-2(3H)-one Derivatives

(2009) Daniele Zampieri et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evaluation of Spirocyclic 3-(3-Fluoropropyl)-2-benzofurans as σ1Receptor Ligands for Neuroimaging with Positron Emission Tomography

(2009) Eva Große Maestrup et al.   JOURNAL OF MEDICINAL CHEMISTRY

Establishment of Broadly Applicable Reaction Conditions for the Palladium-Catalyzed Direct Arylation of Heteroatom-Containing Aromatic Compounds

(2009) Benoît Liégault et al.   JOURNAL OF ORGANIC CHEMISTRY

Programmed Synthesis of Tetraarylthiophenes through Sequential C−H Arylation

(2009) Shuichi Yanagisawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The pharmacology of sigma-1 receptors

(2009) Tangui Maurice et al.   PHARMACOLOGY & THERAPEUTICS

Thiophene Bioisosteres of Spirocyclic σ Receptor Ligands. 1. N-Substituted Spiro[piperidine-4,4′-thieno[3,2-c]pyrans]

(2008) Christoph Oberdorf et al.   JOURNAL OF MEDICINAL CHEMISTRY

A General Method for Copper-Catalyzed Arylation of Arene C−H Bonds

(2008) Hien-Quang Do et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct coupling of arenes and iodoarenes catalyzed by a rhodium complex with a strongly π-accepting phosphite ligand

(2008) Shuichi Yanagisawa et al.   TETRAHEDRON