Exploitation of an additional hydrophobic pocket of σ1 receptors: Late-stage diverse modifications of spirocyclic thiophenes by C–H bond functionalization

Oxidative Biaryl Coupling of Thiophenes and Thiazoles with Arylboronic Acids through Palladium Catalysis: Otherwise Difficult C4-Selective CH Arylation Enabled by Boronic Acids

(2011) Sylvia Kirchberg et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design, synthesis and pharmacological evaluation of spirocyclic σ1 receptor ligands with exocyclic amino moiety (increased distance 1)

(2011) Elisabeth Rack et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Palladium/2,2′-bipyridyl/Ag2CO3 catalyst for C–H bond arylation of heteroarenes with haloarenes

(2011) Shuichi Yanagisawa et al.   TETRAHEDRON

A General Catalyst for the β-Selective C-H Bond Arylation of Thiophenes with Iodoarenes

(2010) Kirika Ueda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

5D-QSAR for spirocyclic σ1 receptor ligands by Quasar receptor surface modeling

(2010) Christoph Oberdorf et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Voltage-gated sodium channel modulation by σ-receptors in cardiac myocytes and heterologous systems

(2009) Molly Johannessen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Iridium Catalysis for CH Bond Arylation of Heteroarenes with Iodoarenes

(2009) Benoît Join et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-Metal-Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage

(2009) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of spirocyclic σ1 receptor ligands as potential PET radiotracers, structure–affinity relationships and in vitro metabolic stability

(2009) Eva Große Maestrup et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Dancing of the Second Aromatic Residue around the 6,8-Diazabicyclo[3.2.2]nonane Framework: Influence on σ Receptor Affinity and Cytotoxicity

(2009) Ralph Holl et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Biological Evaluation, and Three-Dimensional in Silico Pharmacophore Model for σ1Receptor Ligands Based on a Series of Substituted Benzo[d]oxazol-2(3H)-one Derivatives

(2009) Daniele Zampieri et al.   JOURNAL OF MEDICINAL CHEMISTRY

Establishment of Broadly Applicable Reaction Conditions for the Palladium-Catalyzed Direct Arylation of Heteroatom-Containing Aromatic Compounds

(2009) Benoît Liégault et al.   JOURNAL OF ORGANIC CHEMISTRY

Programmed Synthesis of Tetraarylthiophenes through Sequential C−H Arylation

(2009) Shuichi Yanagisawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The pharmacology of sigma-1 receptors

(2009) Tangui Maurice et al.   PHARMACOLOGY & THERAPEUTICS

Thiophene Bioisosteres of Spirocyclic σ Receptor Ligands. 1. N-Substituted Spiro[piperidine-4,4′-thieno[3,2-c]pyrans]

(2008) Christoph Oberdorf et al.   JOURNAL OF MEDICINAL CHEMISTRY

A General Method for Copper-Catalyzed Arylation of Arene C−H Bonds

(2008) Hien-Quang Do et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct coupling of arenes and iodoarenes catalyzed by a rhodium complex with a strongly π-accepting phosphite ligand

(2008) Shuichi Yanagisawa et al.   TETRAHEDRON