Article
Psychology, Multidisciplinary
Oezlem Akin, Nueluefer Erbil
Summary: This study examines PMS in university students and their coping behaviors. 452 female students participated in the study. It was found that 80.5% of students experienced PMS symptoms. Seeking positive affect-inducing activities was identified as a significant predictor for reducing the severity of PMS.
CURRENT PSYCHOLOGY
(2023)
Review
Nutrition & Dietetics
Rodica Siminiuc, Dinu Turcanu
Summary: Premenstrual syndrome (PMS) is a common disorder for women, with over 200 identified symptoms. The study shows that diet plays a crucial role in managing PMS, although there is a lack of scientific evidence on the actual effect of foods and nutrients. The effectiveness of certain micronutrients and herbal supplements has been demonstrated, but more research is needed to support their use as an effective treatment for PMS.
FRONTIERS IN NUTRITION
(2023)
Article
Public, Environmental & Occupational Health
Mingzhou Gao, Dongmei Gao, Hui Sun, Xunshu Cheng, Li An, Mingqi Qiao
Summary: The global scientific output of research on PMS and PMDD has been increasing from 1945 to 2018, with menstrual cycle, depression, and ovarian hormones identified as research hotspots, while prevalence, systematic review, anxiety and depression, and young women are considered the research frontiers.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Health Care Sciences & Services
Young-Joo Park, Hyunjeong Shin, Songi Jeon, Inhae Cho, Yae-Ji Kim
Summary: This study investigated menstrual health among young Korean women and found that menarche was later in the irregular menstruation group. Most women with regular menstruation had normal cycle frequency and duration, but a significant proportion had heavy menstrual bleeding. The irregular menstrual group had higher percentages of underweight and obese women.
Review
Endocrinology & Metabolism
Estrada-Camarena Erika, Carolina Lopez-Rubalcava
Summary: Around 80% of women worldwide experience mild Premenstrual Disorders (PMD) during their reproductive life, with up to a quarter affected by moderate to severe symptoms. Ovarian hormones participate in PMDD symptoms, and their regulation may be altered. PMDD is a complex condition that requires consideration of multiple factors, particularly in animal models.
FRONTIERS IN NEUROENDOCRINOLOGY
(2022)
Article
Psychiatry
Tory Eisenlohr-Moul, Madeline Divine, Katja Schmalenberger, Laura Murphy, Brett Buchert, Melissa Wagner-Schuman, Alyssa Kania, Sabina Raja, Adam Bryant Miller, Jordan Barone, Jaclyn Ross
Summary: This study found high rates of self-injurious thoughts and behaviors in individuals reporting a diagnosis of PMDD, emphasizing the need for further research on understanding and preventing STBs in PMDD. Clinical practice guidelines for PMDD should address comorbidities and include frequent screenings for suicide risk. STBs should be considered for inclusion in future updates of the DSM PMDD diagnostic criteria.
Article
Behavioral Sciences
Liisa Hantsoo, Jennifer L. Payne
Summary: Premenstrual dysphoric disorder (PMDD) is a severe mood disorder that is associated with hormonal fluctuations, and its underlying biology is not yet fully understood. Recent research suggests that abnormal central nervous system response to neuroactive steroid hormone fluctuations, alterations in serotonergic and GABA transmission, genetic heritability, and cellular vulnerability to sex hormones may contribute to PMDD. However, the findings have not yet been integrated into a complete description of PMDD's underlying biology, and a subtyping approach may be beneficial for future research.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Clinical Neurology
Mitchel Kappen, Sofie Raeymakers, Steven Weyers, Marie -Anne Vanderhasselt
Summary: This study investigated the relationship between PMS symptom severity and depression, anxiety, stress, and rumination. The results showed that participants with higher severity of PMS symptoms had higher scores on depressive symptoms, anxiety, stress, and rumination. The study also found that momentary stress and stress-related perseverative rumination increased with increased PMS symptoms.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Review
Endocrinology & Metabolism
Jordan C. Barone, Mitchell P. Butler, Ashley Ross, Anna Patterson, Melissa Wagner-Schuman, Tory A. Eisenlohr-Moul
Summary: Cyclic hormonal variations during the menstrual cycle contribute to multiple central nervous system disorders, such as premenstrual mood disorder, menstrual migraine, and catamenial epilepsy. However, these fields have operated independently without systematic communication. This scoping review examines existing research studies in these disorders to outline hormonal manipulation trials and identify gaps in the literature. Despite the heterogeneity of treatments and study designs, there is significant overlap in the neuroendocrine-based hormone sensitivity among these menstrual cycle-related disorders.
FRONTIERS IN NEUROENDOCRINOLOGY
(2023)
Review
Psychiatry
E. Osborn, J. Brooks, P. M. S. O'Brien, A. Wittkowski
Summary: Female individuals with Premenstrual Dysphoric Disorder (PMDD) are at a higher risk of suicidal thoughts, ideation, plans, and attempts, but do not necessarily present a more severe risk profile in terms of impulsivity, frequency, and lethality compared to suicide attempters without PMDD. Identifying and treating symptoms of PMDD can help reduce suicide attempts in this high-risk group. Implications for clinical practice are discussed in the review.
ARCHIVES OF WOMENS MENTAL HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Wanhyung Lee, Seunghyun Lee, Joonho Ahn, Ryoon Sun Lee, Seong-Kyu Kang
Summary: This study using a follow-up design describes the status, trend, and risk factors of PMS among middle-aged working women, finding an increasing incidence of PMS over an eight-year period and identifying age, occupation, anemia, and underweight as significant risk factors for PMS.
Article
Psychiatry
Aysenur Turan, Iffet Guler Kaya, Hilal Basak Cakir, Secil Topaloglu
Summary: This study investigated the prevalence and correlates of PMS and PMDD in 1125 female college students aged 18-25. The findings showed that approximately 49.2% of participants had PMS and 48.0% had PMDD. Blood type B, lack of physical activity, longer menstrual cycle duration, and higher caffeine intake were associated with PMS and PMDD.
INTERNATIONAL JOURNAL OF PSYCHIATRY IN MEDICINE
(2023)
Article
Nutrition & Dietetics
Zana Stanic, Ajka Pribisalic, Maria Boskovic, Jasna Bucan Cvitanic, Kristina Boban, Gabriela Baskovic, Antonija Bartulic, Suzana Demo, Ozren Polasek, Ivana Kolcic
Summary: The study aimed to clarify conflicting findings on the influence of the menstrual cycle on olfactory and gustatory perception. Results showed that women followed across a complete menstrual cycle exhibited linear increases in olfactory discrimination, identification, and overall olfactory performance. Compared to other groups, these women displayed a cyclic pattern characterized by a preference for sweet solutions, reduced distaste for salty and sour solutions, and increased intensity perception of salty, sour, and bitter solutions towards the end of the cycle.
Article
Psychology, Clinical
Sibel Nayman, Theresa Beddig, Iris Reinhard, Christine Kuehner
Summary: In women with premenstrual dysphoric disorder (PMDD), habitual mindfulness and reappraisal have a positive effect on momentary mood, but do not protect against premenstrual mood deterioration. Additionally, habitual mindfulness seems to buffer blunted cortisol activity in women with PMDD, especially during the menstrual phase.
PSYCHOLOGICAL MEDICINE
(2023)
Review
Psychiatry
Christine Kuehner, Sibel Nayman
Summary: Research on premenstrual exacerbations (PME) of ongoing mood disorders is scarce compared to premenstrual dysphoric disorder (PMDD). Studies suggest that around 60% of women with mood disorders experience PME, with some bipolar disorder patients also showing symptoms exacerbations around ovulation. PME predicts a more severe illness course and increased burden, with unclear overlap of underlying biological mechanisms with PMDD.
CURRENT PSYCHIATRY REPORTS
(2021)
Editorial Material
Medicine, General & Internal
Lijuan Sun, Hui Jen Goh, Nan Xin Wang, Sanjay K. Verma, S. Sendhil Velan, Melvin Khee Shing Leow
POSTGRADUATE MEDICAL JOURNAL
(2022)
Article
Nutrition & Dietetics
Stefan Gerardus Camps, Huann Rong Koh, Christiani Jeyakumar Henry
Summary: The effect of metabolic state on the energy cost of posture allocation was examined in this study. The difference between energy spenders and energy savers in a fasted state disappeared after the consumption of a meal. The findings suggest that metabolic state should be taken into account when assessing metabolic phenotypes.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Food Science & Technology
Xin Yi Hua, Jie Hong Chiang, Christiani Jeyakumar Henry
Summary: This study demonstrates the potential of using plant proteins as alternative emulsifiers in double emulsion fabrication, which can improve stability and lower production costs. Microcapsules formed by complex coacervation at pH 2 showed the highest stability, highlighting the effectiveness of this method for delivering bioactive compounds.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Melvin Khee-Shing Leow, Anantharaj Rengaraj, Kothandaraman Narasimhan, Sanjay K. Verma, Jadegoud Yaligar, Giang Le Thi Thu, Lijuan Sun, Hui Jen Goh, Priya Govindharajulu, Suresh Anand Sadananthan, Navin Michael, Wei Meng, Xavier Gallart-Palau, Lei Sun, Neerja Karnani, Newman Siu Kwan Sze, S. Sendhil Velan
Summary: Brown adipose tissue (BAT) is a promising weapon against obesity and metabolic disease, and its activity can be assessed through the release of exosomes from brown adipocytes in the blood plasma. In humans, the exosomal protein MTHFD1L can accurately and reliably reflect BAT activation.
BIOSCIENCE REPORTS
(2022)
Article
Multidisciplinary Sciences
Lijuan Sun, Hui Jen Goh, Sanjay Verma, Priya Govindharajulu, Suresh Anand Sadananthan, Navin Michael, Christiani Jeyakumar Henry, Julian Park-Nam Goh, S. Sendhil Velan, Melvin Khee-Shing Leow
Summary: This study investigates changes in amino acids, specifically branched chain amino acids (BCAA), during the transition from hyperthyroidism to euthyroidism and the impact of active brown adipose tissue (BAT) on BCAA metabolism. The results show that active BAT can potentially reduce circulating BCAA levels and help improve insulin resistance and metabolic health.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Applied
Jie Hong Chiang, Michelle Ting Yun Yeo, Dayna Shu Min Ong, Christiani Jeyakumar Henry
Summary: The changes in the molecular properties and volatile compounds of Maillard reaction products obtained from chicken bone extract (CBE), wheat protein (WP), and rice protein (RP) hydrolysates were compared in this study. It was concluded that these products could be used as potential natural flavors.
Review
Food Science & Technology
Jie Hong Chiang, Xin Yi Hua, Ashley Hui Min Yu, Elaine Wan Yi Peh, E'Ein See, Christiani Jeyakumar Henry
Summary: This review provides an overview of the health benefits of buckwheat as a whole grain food, particularly its hypoglycemic property. The extraction process, types of bioactive components, and mechanisms of action are discussed, along with the effects of thermal treatments on functional and digestibility properties. The application of buckwheat in foods and diets, as well as in vitro and in vivo studies on glycemia, are also mentioned.
FOOD REVIEWS INTERNATIONAL
(2023)
Article
Public, Environmental & Occupational Health
Wesley Tay, Rina Quek, Bhupinder Kaur, Joseph Lim, Christiani Jeyakumar Henry
Summary: This study discusses the feasibility of using facial morphometrics as a novel digital method for diagnosing malnutrition. By digitizing facial features, the subtle changes in nutritional status can be quantified. This method enables remote monitoring and management of nutrition issues, providing essential information for healthcare professionals, institutions, and policymakers.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2022)
Editorial Material
Endocrinology & Metabolism
Melvin K. S. Leow
Summary: This article discusses the strengths and pitfalls of infrared thermography (IRT) as an emergent BAT detection technique and provides a mathematical proof of its limitations. Understanding these limitations of IRT can prompt extra efforts to control these uncertainties and enhance the quality of IRT.
ENDOCRINOLOGY DIABETES & METABOLISM
(2023)
Article
Food Science & Technology
Felicia Siew Kay Ng, Jie Hong Chiang, Grace Cui Fang Ng, Cheryl Si Hui Lee, Christiani Jeyakumar Henry
Summary: This study investigated the suitability of plant-based proteins and fats as substitutes for dairy ingredients in developing frozen desserts. The plant-based desserts had comparable nutrition profiles to dairy desserts but higher dietary fiber content, resulting in improved texture and taste. The desserts containing both chickpea protein concentrate and soymilk powder showed the highest sensory scores and can be a suitable food supplement for elderly individuals at risk of malnutrition.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Biology
Qiuzhong Zhou, Yuxi Jiang, Chaoqun Cai, Wen Li, Melvin Khee-Shing Leow, Yi Yang, Jin Liu, Dan Xu, Lei Sun
Summary: In this study, the conservation between human and mouse lncRNAs was evaluated from various dimensions using multiple approaches, including sequences, promoter, global synteny, and local synteny. A total of 1,731 conserved lncRNAs were identified, with 427 high-confidence ones meeting multiple criteria. Conserved lncRNAs showed longer gene bodies, more exons and transcripts, stronger connections with human diseases, and were more abundant and widespread across different tissues compared to non-conserved ones. Transcription factor profile analysis revealed an enrichment of TF types and numbers in the promoters of conserved lncRNAs. A set of TFs that preferentially bind to conserved lncRNAs and exert stronger regulation on them were also identified.
LIFE SCIENCE ALLIANCE
(2023)
Article
Nutrition & Dietetics
Wesley Tay, Rina Quek, Joseph Lim, Bhupinder Kaur, Shalini Ponnalagu, Christiani Jeyakumar Henry
Summary: This study aims to model the replacement of a diet consisting of animal-based proteins with plant-based alternatives in a group of Asians. The results showed that the consumption of plant-based alternatives led to a significant increase in carbohydrates, dietary fiber, sodium, and calcium intake, but a significant decrease in overall energy, protein, and fat intake. The substitution of animal-based proteins with plant-based alternatives may have benefits for bone health and individuals on a caloric restriction diet, but may also have negative effects on individuals with cardiovascular conditions and hypertension, as well as iron deficient populations.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2023)
Letter
Food Science & Technology
Darel Wee Kiat Toh, S. R. V. Akila, Christiani Jeyakumar Henry
Article
Health Policy & Services
Fanwen Meng, Aidan Lyanzhiang Tan, Bee Hoon Heng, Melvin Khee Shing Leow, Palvannan Kannapiran
Summary: The increasing prevalence of chronic diseases poses a considerable concern to healthcare organisations. This study aims to analyze the feasibility of prevention programs for patients with early chronic diseases, by determining the minimum reduction rate of incidence that leads to the break-even of underlying costs through a mathematical model. The proposed model demonstrates the efficiency and advantages of a diabetes prevention program and provides scientific principles for decision-makers in implementing interventions.