The suppression of epileptiform discharges in cultured hippocampal neurons is regulated via alterations in full-length tropomyosin-related kinase type B receptors signalling activity

Blocking brain-derived neurotrophic factor inhibits injury-induced hyperexcitability of hippocampal CA3 neurons

(2013) Raminder Gill et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The PPARγ agonist rosiglitazone prevents neuronal loss and attenuates development of spontaneous recurrent seizures through BDNF/TrkB signaling following pilocarpine-induced status epilepticus

(2013) Sun Hong et al.   NEUROCHEMISTRY INTERNATIONAL

Transient Inhibition of TrkB Kinase after Status Epilepticus Prevents Development of Temporal Lobe Epilepsy

(2013) Gumei Liu et al.   NEURON

Truncated TrkB: Beyond a dominant negative receptor

(2012) Barbara M. Fenner   CYTOKINE & GROWTH FACTOR REVIEWS

Molecular pathways controlling inhibitory receptor expression

(2012) Heidi L. Grabenstatter et al.   EPILEPSIA

Regulators of synaptic transmission: Roles in the pathogenesis and treatment of epilepsy

(2012) Pablo M. Casillas-Espinosa et al.   EPILEPSIA

The cellular and synaptic location of activated TrkB in mouse hippocampus during limbic epileptogenesis

(2012) Jeffrey Helgager et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Excitotoxicity Downregulates TrkB.FL Signaling and Upregulates the Neuroprotective Truncated TrkB Receptors in Cultured Hippocampal and Striatal Neurons

(2012) J. R. Gomes et al.   JOURNAL OF NEUROSCIENCE

Brain-derived neurotrophic factor–estrogen interactions in the hippocampal mossy fiber pathway: Implications for normal brain function and disease

(2012) L.C. Harte-Hargrove et al.   NEUROSCIENCE

Deletion of the BDNF Truncated Receptor TrkB.T1 Delays Disease Onset in a Mouse Model of Amyotrophic Lateral Sclerosis

(2012) Sudhirkumar U. Yanpallewar et al.   PLoS One

Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity

(2012) Ó G Vidaurre et al.   Cell Death & Disease

Cleavage of the Vesicular GABA Transporter under Excitotoxic Conditions Is Followed by Accumulation of the Truncated Transporter in Nonsynaptic Sites

(2011) J. R. Gomes et al.   JOURNAL OF NEUROSCIENCE

Working memory deficits, increased anxiety-like traits, and seizure susceptibility in BDNF overexpressing mice

(2011) F. Papaleo et al.   LEARNING & MEMORY

Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice

(2011) Susanna Kemppainen et al.   NEUROBIOLOGY OF AGING

Increase in BDNF-mediated TrkB signaling promotes epileptogenesis in a mouse model of mesial temporal lobe epilepsy

(2011) Christophe Heinrich et al.   NEUROBIOLOGY OF DISEASE

BDNF-secreting capsule exerts neuroprotective effects on epilepsy model of rats

(2010) Satoshi Kuramoto et al.   BRAIN RESEARCH

Human TrkB gene: novel alternative transcripts, protein isoforms and expression pattern in the prefrontal cerebral cortex during postnatal development

(2010) Kristi Luberg et al.   JOURNAL OF NEUROCHEMISTRY

Disruption of TrkB-Mediated Phospholipase C  Signaling Inhibits Limbic Epileptogenesis

(2010) X. P. He et al.   JOURNAL OF NEUROSCIENCE

Brain-derived neurotrophic factor facilitates TrkB down-regulation and neuronal injury after status epilepticus in the rat hippocampus

(2009) Nicolás Unsain et al.   JOURNAL OF NEUROCHEMISTRY

Endogenous Truncated TrkB.T1 Receptor Regulates Neuronal Complexity and TrkB Kinase Receptor Function In Vivo

(2009) L. Carim-Todd et al.   JOURNAL OF NEUROSCIENCE

TrkB signalling pathways in LTP and learning

(2009) Liliana Minichiello   NATURE REVIEWS NEUROSCIENCE

The basal level of intracellular calcium gates the activation of phosphoinositide 3-kinase-Akt signaling by brain-derived neurotrophic factor in cortical neurons

(2008) Fei Zheng et al.   JOURNAL OF NEUROCHEMISTRY

Calpain activity contributes to the control of SNAP-25 levels in neurons

(2008) Carlotta Grumelli et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Balanced expression of various TrkB receptor isoforms from the Ntrk2 gene locus in the mouse nervous system

(2008) Haruko Kumanogoh et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Status epilepticus induces a TrkB to p75 neurotrophin receptor switch and increases brain-derived neurotrophic factor interaction with p75 neurotrophin receptor: An initial event in neuronal injury induction

(2008) N. Unsain et al.   NEUROSCIENCE

Brain-derived neurotrophic factor and its receptor tropomyosin-related kinase B in the mechanism of action of antidepressant therapies

(2007) Megan E. Kozisek et al.   PHARMACOLOGY & THERAPEUTICS