TLRs to cytokines: Mechanistic insights from the imiquimod mouse model of psoriasis

A 9-Centimorgan Interval of Chromosome 10 Controls the T Cell-Dependent Psoriasiform Skin Disease and Arthritis in a Murine Psoriasis Model

(2014) H. Wang et al.   JOURNAL OF IMMUNOLOGY

IL-1R1 Signaling Facilitates Munro’s Microabscess Formation in Psoriasiform Imiquimod-Induced Skin Inflammation

(2013) Mireia Uribe-Herranz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues

(2013) Jochem H Bernink et al.   NATURE IMMUNOLOGY

Langerinneg conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice

(2013) C. Wohn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aldara activates TLR7-independent immune defence

(2013) Anne Walter et al.   Nature Communications

IL-17-producing γδ T cells and innate lymphoid cells

(2012) Caroline E. Sutton et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-23: One cytokine in control of autoimmunity

(2012) Andrew L. Croxford et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Stroma-Derived Interleukin-34 Controls the Development and Maintenance of Langerhans Cells and the Maintenance of Microglia

(2012) Melanie Greter et al.   IMMUNITY

Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice

(2012) Stanislav Pantelyushin et al.   JOURNAL OF CLINICAL INVESTIGATION

Imiquimod clears tumors in mice independent of adaptive immunity by converting pDCs into tumor-killing effector cells

(2012) Barbara Drobits et al.   JOURNAL OF CLINICAL INVESTIGATION

Psoriasiform dermatitis is driven by IL-36–mediated DC-keratinocyte crosstalk

(2012) Luigi Tortola et al.   JOURNAL OF CLINICAL INVESTIGATION

Remission of psoriasis after allogeneic, but not autologous, hematopoietic stem-cell transplantation

(2012) Benjamin H. Kaffenberger et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

(2012) Lam C Tsoi et al.   NATURE GENETICS

Compartmentalized Control of Skin Immunity by Resident Commensals

(2012) S. Naik et al.   SCIENCE

Mutations in IL36RN/IL1F5 Are Associated with the Severe Episodic Inflammatory Skin Disease Known as Generalized Pustular Psoriasis

(2011) Alexandros Onoufriadis et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Pivotal Role of Dermal IL-17-Producing γδ T Cells in Skin Inflammation

(2011) Yihua Cai et al.   IMMUNITY

IL-17 and IL-22 enhance skin inflammation by stimulating the secretion of IL-1β by keratinocytes via the ROS-NLRP3-caspase-1 pathway

(2011) Kyung-Ah Cho et al.   INTERNATIONAL IMMUNOLOGY

Involvement of Tyrosine Kinase-2 in Both the IL-12/Th1 and IL-23/Th17 Axes In Vivo

(2011) M. Ishizaki et al.   JOURNAL OF IMMUNOLOGY

IL-22 Is Required for Imiquimod-Induced Psoriasiform Skin Inflammation in Mice

(2011) A. B. Van Belle et al.   JOURNAL OF IMMUNOLOGY

IL-1F5, -F6, -F8, and -F9: A Novel IL-1 Family Signaling System That Is Active in Psoriasis and Promotes Keratinocyte Antimicrobial Peptide Expression

(2011) A. Johnston et al.   JOURNAL OF IMMUNOLOGY

Identification of a Novel Proinflammatory Human Skin-Homing V 9V 2 T Cell Subset with a Potential Role in Psoriasis

(2011) U. Laggner et al.   JOURNAL OF IMMUNOLOGY

Genetics and pathogenesis of inflammatory bowel disease

(2011) Bernard Khor et al.   NATURE

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner

(2011) Vladimir Ramirez-Carrozzi et al.   NATURE IMMUNOLOGY

Genome-Wide Expression Profiling of Five Mouse Models Identifies Similarities and Differences with Human Psoriasis

(2011) William R. Swindell et al.   PLoS One

Impaired Mast Cell-Driven Immune Responses in Mice Lacking the Transcription Factor NFATc2

(2009) Marc Becker et al.   JOURNAL OF IMMUNOLOGY

Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis

(2009) L. van der Fits et al.   JOURNAL OF IMMUNOLOGY

TLR7 and TLR8 agonists trigger different signaling pathways for human dendritic cell maturation

(2009) A. Larange et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Psoriasis

(2009) Frank O. Nestle et al.   NEW ENGLAND JOURNAL OF MEDICINE

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

(2008) Michelle A. Lowes et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Substantial Alterations of the Cutaneous Bacterial Biota in Psoriatic Lesions

(2008) Zhan Gao et al.   PLoS One